Woodhams SG et al. |
Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. |
2012 |
Br. J. Pharmacol. |
pmid:22924700
|
Wang M et al. |
Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation. |
2012 |
J. Psychopharmacol. (Oxford) |
pmid:21890595
|
Oleson EB et al. |
Endocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum. |
2012 |
Neuron |
pmid:22284189
|
Mimura T et al. |
Involvement of the endogenous cannabinoid 2 ligand 2-arachidonyl glycerol in allergic inflammation. |
2012 |
Int. Arch. Allergy Immunol. |
pmid:22652530
|
Jung KM et al. |
2-arachidonoylglycerol signaling in forebrain regulates systemic energy metabolism. |
2012 |
Cell Metab. |
pmid:22405068
|
Xu JY et al. |
Long-lasting potentiation of hippocampal synaptic transmission by direct cortical input is mediated via endocannabinoids. |
2012 |
J. Physiol. (Lond.) |
pmid:22411015
|
Echigo R et al. |
Cannabinoids inhibit peptidoglycan-induced phosphorylation of NF-κB and cell growth in U87MG human malignant glioma cells. |
2012 |
Oncol. Rep. |
pmid:22842590
|
Kortleven C et al. |
Neurotensin inhibits glutamate-mediated synaptic inputs onto ventral tegmental area dopamine neurons through the release of the endocannabinoid 2-AG. |
2012 |
Neuropharmacology |
pmid:22884466
|
Czifra G et al. |
Endocannabinoids regulate growth and survival of human eccrine sweat gland-derived epithelial cells. |
2012 |
J. Invest. Dermatol. |
pmid:22513781
|
Tanimura A et al. |
Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22783023
|
Caprioli A et al. |
The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22514334
|
Dubreucq S et al. |
Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice. |
2012 |
Neuropsychopharmacology |
pmid:22434220
|
Pucci M et al. |
Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor. |
2012 |
J. Biol. Chem. |
pmid:22431736
|
McLaughlin RJ et al. |
Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway. |
2012 |
Eur Neuropsychopharmacol |
pmid:22325231
|
Ritter JK et al. |
Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22685343
|
Chicca A et al. |
The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. |
2012 |
Br. J. Pharmacol. |
pmid:22646533
|
Tanveer R et al. |
The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats. |
2012 |
J. Biol. Chem. |
pmid:22891244
|
Chicca A et al. |
Evidence for bidirectional endocannabinoid transport across cell membranes. |
2012 |
J. Biol. Chem. |
pmid:22879589
|
Sticht MA et al. |
Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats. |
2012 |
Br. J. Pharmacol. |
pmid:21470205
|
Jones BR et al. |
Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules. |
2012 |
Bioanalysis |
pmid:23088461
|
Jung KM et al. |
Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. |
2012 |
Nat Commun |
pmid:23011134
|
Gyombolai P et al. |
Regulation of endocannabinoid release by G proteins: a paracrine mechanism of G protein-coupled receptor action. |
2012 |
Mol. Cell. Endocrinol. |
pmid:22075205
|
Song J et al. |
Gating the polarity of endocannabinoid-mediated synaptic plasticity by nitric oxide in the spinal locomotor network. |
2012 |
J. Neurosci. |
pmid:22496555
|
Raman P et al. |
15-Deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor γ ligand, modulates nuclear factor of activated T cells. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22700433
|
Katona I and Freund TF |
Multiple functions of endocannabinoid signaling in the brain. |
2012 |
Annu. Rev. Neurosci. |
pmid:22524785
|
Gould GG et al. |
Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice. |
2012 |
Prog. Neuropsychopharmacol. Biol. Psychiatry |
pmid:22542870
|
Ueda N et al. |
Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol. |
2011 Jan-Feb |
Biofactors |
pmid:21328621
|
Frazier CJ |
Key questions of endocannabinoid signalling in the CNS: which, where and when? |
2011 |
J. Physiol. (Lond.) |
pmid:22001725
|
Nomura DK et al. |
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation. |
2011 |
Science |
pmid:22021672
|
Muppidi JR et al. |
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. |
2011 |
J. Exp. Med. |
pmid:21875957
|
Zhang L et al. |
Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase. |
2011 |
PLoS ONE |
pmid:21305054
|
Schalk-Hihi C et al. |
Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Ã… resolution. |
2011 |
Protein Sci. |
pmid:21308848
|
Duggan KC et al. |
(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. |
2011 |
Nat. Chem. Biol. |
pmid:22053353
|
Higuchi S et al. |
Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors. |
2011 |
Behav. Brain Res. |
pmid:20817042
|
Ludányi A et al. |
Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. |
2011 |
Neuroscience |
pmid:21035522
|
Hofmann ME et al. |
Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. |
2011 |
J. Physiol. (Lond.) |
pmid:21646412
|
Chanda D et al. |
Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes. |
2011 |
J. Biol. Chem. |
pmid:21693703
|
Signorello MG et al. |
Activation of human platelets by 2-arachidonoylglycerol: role of PKC in NO/cGMP pathway modulation. |
2011 |
Curr Neurovasc Res |
pmid:21675954
|
Marrs WR et al. |
Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons. |
2011 |
J. Biol. Chem. |
pmid:21665953
|
Gantayet A et al. |
Endocannabinoids and diacylglycerol kinase activity. |
2011 |
Biochim. Biophys. Acta |
pmid:21194521
|
Howlett AC et al. |
Endocannabinoid tone versus constitutive activity of cannabinoid receptors. |
2011 |
Br. J. Pharmacol. |
pmid:21545414
|
Sciolino NR et al. |
Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats. |
2011 |
Pharmacol. Res. |
pmid:21600985
|
Uchigashima M et al. |
Molecular and morphological configuration for 2-arachidonoylglycerol-mediated retrograde signaling at mossy cell-granule cell synapses in the dentate gyrus. |
2011 |
J. Neurosci. |
pmid:21613483
|
Alhouayek M et al. |
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. |
2011 |
FASEB J. |
pmid:21551239
|
Justinová Z et al. |
The endogenous cannabinoid 2-arachidonoylglycerol is intravenously self-administered by squirrel monkeys. |
2011 |
J. Neurosci. |
pmid:21562266
|
Borges BC et al. |
Leptin resistance and desensitization of hypophagia during prolonged inflammatory challenge. |
2011 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:21343543
|
Shekhar C |
Mixed signals: cannabinoid system offers new therapeutic possibilities as well as challenges. |
2011 |
Chem. Biol. |
pmid:21609833
|
Ho YC et al. |
Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. |
2011 |
J. Neurosci. |
pmid:21994376
|
Cippitelli A et al. |
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. |
2011 |
PLoS ONE |
pmid:22140525
|
Yoshino H et al. |
Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. |
2011 |
J. Physiol. (Lond.) |
pmid:21807615
|