| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ganglion Cysts | D045888 | 1 associated lipids |
| Fetal Nutrition Disorders | D048070 | 1 associated lipids |
| Neuromyelitis Optica | D009471 | 2 associated lipids |
| Acute Pain | D059787 | 3 associated lipids |
| Fragile X Syndrome | D005600 | 5 associated lipids |
| Head Injuries, Closed | D016489 | 5 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Cholangiocarcinoma | D018281 | 7 associated lipids |
| Hepatic Encephalopathy | D006501 | 9 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Hyperkinesis | D006948 | 11 associated lipids |
| Encephalitis | D004660 | 15 associated lipids |
| Liver Cirrhosis, Alcoholic | D008104 | 17 associated lipids |
| Hypothermia | D007035 | 19 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
| Hypoxia-Ischemia, Brain | D020925 | 22 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sinor AD et al. | Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats. | 2000 | Neurosci. Lett. | pmid:10653017 |
| Sugiura T and Waku K | 2-Arachidonoylglycerol and the cannabinoid receptors. | 2000 | Chem. Phys. Lipids | pmid:11106784 |
| Gallily R et al. | 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice. | 2000 | Eur. J. Pharmacol. | pmid:11011050 |
| Chen Y et al. | Human brain capillary endothelium: 2-arachidonoglycerol (endocannabinoid) interacts with endothelin-1. | 2000 | Circ. Res. | pmid:10948067 |
| Suhara Y et al. | Synthesis and biological activities of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, and its metabolically stable ether-linked analogues. | 2000 | Chem. Pharm. Bull. | pmid:10923815 |
| Járai Z et al. | Cardiovascular effects of 2-arachidonoyl glycerol in anesthetized mice. | 2000 | Hypertension | pmid:10679517 |
| Ameri A and Simmet T | Effects of 2-arachidonylglycerol, an endogenous cannabinoid, on neuronal activity in rat hippocampal slices. | 2000 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10731038 |
| Melck D et al. | Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. | 2000 | Endocrinology | pmid:10614630 |
| Hillard CJ | Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785538 |
| Di Marzo V et al. | Cannabimimetic fatty acid derivatives in cancer and inflammation. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785541 |
| Schmid PC et al. | A sensitive endocannabinoid assay. The simultaneous analysis of N-acylethanolamines and 2-monoacylglycerols. | 2000 | Chem. Phys. Lipids | pmid:10669310 |
| González S et al. | Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733937 |
| Fowler CJ et al. | Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. | 2001 | Biochem. Pharmacol. | pmid:11585048 |
| Baker D et al. | Endocannabinoids control spasticity in a multiple sclerosis model. | 2001 | FASEB J. | pmid:11156943 |
| Al-Hayani A et al. | The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. | 2001 | Neuropharmacology | pmid:11747904 |
| Kagota S et al. | 2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor. | 2001 | Eur. J. Pharmacol. | pmid:11275004 |
| Sugiura T et al. | Rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain after decapitation. | 2001 | Neurosci. Lett. | pmid:11137756 |
| Wang Y et al. | Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. | 2001 | Anal. Biochem. | pmid:11412008 |
| Panikashvili D et al. | An endogenous cannabinoid (2-AG) is neuroprotective after brain injury. | 2001 | Nature | pmid:11586361 |
| Berdyshev EV et al. | Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells. | 2001 | FASEB J. | pmid:11641243 |