Blankman JL and Cravatt BF |
Chemical probes of endocannabinoid metabolism. |
2013 |
Pharmacol. Rev. |
pmid:23512546
|
Haruna T et al. |
The Inhibitory Effect of S-777469, a Cannabinoid Type 2 Receptor Agonist, on Skin Inflammation in Mice. |
2017 |
Pharmacology |
pmid:28214870
|
Hill MN et al. |
Serum endocannabinoid content is altered in females with depressive disorders: a preliminary report. |
2008 |
Pharmacopsychiatry |
pmid:18311684
|
Reisenberg M et al. |
The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108545
|
Melis M and Pistis M |
Hub and switches: endocannabinoid signalling in midbrain dopamine neurons. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108546
|
Skaper SD and Di Marzo V |
Endocannabinoids in nervous system health and disease: the big picture in a nutshell. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108539
|
Di Marzo V and De Petrocellis L |
Why do cannabinoid receptors have more than one endogenous ligand? |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108541
|
Puighermanal E et al. |
Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108544
|
Starowicz K and Przewlocka B |
Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108547
|
Rani Sagar D et al. |
Dynamic changes to the endocannabinoid system in models of chronic pain. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108548
|
Argueta DA and DiPatrizio NV |
Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity. |
2017 |
Physiol. Behav. |
pmid:28065722
|
Thompson Z et al. |
Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes. |
2017 |
Physiol. Behav. |
pmid:28017680
|
Sticht MA et al. |
2-arachidonoylglycerol interferes with lithium-induced vomiting in the house musk shrew, Suncus murinus. |
2013 |
Physiol. Behav. |
pmid:23958470
|
Pacioni G et al. |
Truffles contain endocannabinoid metabolic enzymes and anandamide. |
2015 |
Phytochemistry |
pmid:25433633
|
Brocato B et al. |
Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. |
2013 |
Placenta |
pmid:24008071
|
Brantl SA et al. |
Activation of platelets by the endocannabinoids 2-arachidonoylglycerol and virodhamine is mediated by their conversion to arachidonic acid and thromboxane A2, not by activation of cannabinoid receptors. |
2014 |
Platelets |
pmid:24102401
|
Brantl SA et al. |
Mechanism of platelet activation induced by endocannabinoids in blood and plasma. |
2014 |
Platelets |
pmid:23789792
|
Gkini E et al. |
Metabolism of 2-acylglycerol in rabbit and human platelets. Involvement of monoacylglycerol lipase and fatty acid amide hydrolase. |
2009 |
Platelets |
pmid:19811221
|
Jehle J et al. |
Elevated levels of 2-arachidonoylglycerol promote atherogenesis in ApoE-/- mice. |
2018 |
PLoS ONE |
pmid:29813086
|
Martins CJ et al. |
Circulating Endocannabinoids and the Polymorphism 385C>A in Fatty Acid Amide Hydrolase (FAAH) Gene May Identify the Obesity Phenotype Related to Cardiometabolic Risk: A Study Conducted in a Brazilian Population of Complex Interethnic Admixture. |
2015 |
PLoS ONE |
pmid:26561012
|
Smith M et al. |
The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on Human Osteoblast Proliferation and Differentiation. |
2015 |
PLoS ONE |
pmid:26414859
|
Fagundo AB et al. |
Modulation of the Endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on Executive Functions in Humans. |
2013 |
PLoS ONE |
pmid:23840456
|
Chon SH et al. |
Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. |
2012 |
PLoS ONE |
pmid:22937137
|
Zhang L et al. |
Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase. |
2011 |
PLoS ONE |
pmid:21305054
|
Wang DJ et al. |
Cytosolic phospholipase A2 alpha/arachidonic acid signaling mediates depolarization-induced suppression of excitation in the cerebellum. |
2012 |
PLoS ONE |
pmid:22927908
|
Nicholson J et al. |
Leptin levels are negatively correlated with 2-arachidonoylglycerol in the cerebrospinal fluid of patients with osteoarthritis. |
2015 |
PLoS ONE |
pmid:25835291
|
Higuchi S et al. |
Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences. |
2012 |
PLoS ONE |
pmid:22737214
|
Özdemir B et al. |
Endocannabinoids and inflammatory response in periodontal ligament cells. |
2014 |
PLoS ONE |
pmid:25226300
|
Kallendrusch S et al. |
Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage. |
2012 |
PLoS ONE |
pmid:23284665
|
Lafourcade M et al. |
Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex. |
2007 |
PLoS ONE |
pmid:17684555
|
Chanda D et al. |
Hepatic cannabinoid receptor type 1 mediates alcohol-induced regulation of bile acid enzyme genes expression via CREBH. |
2013 |
PLoS ONE |
pmid:23894352
|
Pellkofer HL et al. |
The major brain endocannabinoid 2-AG controls neuropathic pain and mechanical hyperalgesia in patients with neuromyelitis optica. |
2013 |
PLoS ONE |
pmid:23951176
|
Costola-de-Souza C et al. |
Monoacylglycerol lipase (MAGL) inhibition attenuates acute lung injury in mice. |
2013 |
PLoS ONE |
pmid:24204926
|
Starowicz K et al. |
Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. |
2013 |
PLoS ONE |
pmid:23573230
|
Zygmunt PM et al. |
Monoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1. |
2013 |
PLoS ONE |
pmid:24312564
|
Pava MJ et al. |
Endocannabinoid modulation of cortical up-states and NREM sleep. |
2014 |
PLoS ONE |
pmid:24520411
|
Cippitelli A et al. |
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. |
2011 |
PLoS ONE |
pmid:22140525
|
Pastor A et al. |
A Lower Olfactory Capacity Is Related to Higher Circulating Concentrations of Endocannabinoid 2-Arachidonoylglycerol and Higher Body Mass Index in Women. |
2016 |
PLoS ONE |
pmid:26849214
|
Jalin AM et al. |
Non-Selective Cannabinoid Receptor Antagonists, Hinokiresinols Reduce Infiltration of Microglia/Macrophages into Ischemic Brain Lesions in Rat via Modulating 2-Arachidonolyglycerol-Induced Migration and Mitochondrial Activity. |
2015 |
PLoS ONE |
pmid:26517721
|
Kita Y et al. |
Fever Is Mediated by Conversion of Endocannabinoid 2-Arachidonoylglycerol to Prostaglandin E2. |
2015 |
PLoS ONE |
pmid:26196692
|
Karabowicz P et al. |
[Role of endocannabinoid 2-arachidonoylglycerol in the physiology and pathophysiology of the cardiovascular system]. |
2014 |
Postepy Hig Med Dosw (Online) |
pmid:24934539
|
Pertwee RG |
Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications. |
2014 |
Proc Nutr Soc |
pmid:24135210
|
Burston JJ and Woodhams SG |
Endocannabinoid system and pain: an introduction. |
2014 |
Proc Nutr Soc |
pmid:24148358
|
Haj-Dahmane S et al. |
Fatty-acid-binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses. |
2018 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:29531087
|
Atsak P et al. |
Glucocorticoids interact with the hippocampal endocannabinoid system in impairing retrieval of contextual fear memory. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22331883
|
Piomelli D et al. |
Structural determinants for recognition and translocation by the anandamide transporter. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10318965
|
Chicca A et al. |
Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake. |
2017 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:28584105
|
Grimaldi P et al. |
The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19541620
|
Morena M et al. |
Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25489086
|
Tanimura A et al. |
Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22783023
|
Adermark L and Lovinger DM |
Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18077376
|
Cristino L et al. |
Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons. |
2013 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:23630288
|
Keimpema E et al. |
Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. |
2013 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:23319656
|
Alhouayek M et al. |
Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6. |
2013 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24101490
|
Lauckner JE et al. |
The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins. |
2005 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16365309
|
Iannotti FA et al. |
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24927567
|
Yoshida T et al. |
Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21282604
|
Witting A et al. |
P2X7 receptors control 2-arachidonoylglycerol production by microglial cells. |
2004 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:14976257
|
Ruby MA et al. |
Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18794527
|
Long JZ et al. |
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19918051
|
Buczynski MW et al. |
Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. |
2016 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26755579
|
Ogasawara D et al. |
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition. |
2016 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26668358
|
Mitchener MM et al. |
Competition and allostery govern substrate selectivity of cyclooxygenase-2. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26392530
|
Dinh TP et al. |
Brain monoglyceride lipase participating in endocannabinoid inactivation. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12136125
|
Calignano A et al. |
A role for the endogenous cannabinoid system in the peripheral control of pain initiation. |
2000 |
Prog. Brain Res. |
pmid:11098711
|
Baggelaar MP et al. |
2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain. |
2018 |
Prog. Lipid Res. |
pmid:29751000
|
Iannotti FA et al. |
Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders. |
2016 |
Prog. Lipid Res. |
pmid:26965148
|
Sugiura T et al. |
Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. |
2006 |
Prog. Lipid Res. |
pmid:16678907
|
Yi B et al. |
Reductions in circulating endocannabinoid 2-arachidonoylglycerol levels in healthy human subjects exposed to chronic stressors. |
2016 |
Prog. Neuropsychopharmacol. Biol. Psychiatry |
pmid:26780604
|
Bystrowska B et al. |
Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. |
2014 |
Prog. Neuropsychopharmacol. Biol. Psychiatry |
pmid:24334211
|
Gould GG et al. |
Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice. |
2012 |
Prog. Neuropsychopharmacol. Biol. Psychiatry |
pmid:22542870
|
Avraham Y et al. |
2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist, in various rat tissues during the evolution of experimental cholestatic liver disease. |
2008 Jul-Aug |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:18771906
|
Sugiura T et al. |
Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. |
2002 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12052034
|
Fowler CJ and Jacobsson SO |
Cellular transport of anandamide, 2-arachidonoylglycerol and palmitoylethanolamide--targets for drug development? |
2002 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12052035
|
Högestätt ED and Zygmunt PM |
Cardiovascular pharmacology of anandamide. |
2002 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12052048
|
Watanabe S et al. |
n-3 Polyunsaturated fatty acid (PUFA) deficiency elevates and n-3 PUFA enrichment reduces brain 2-arachidonoylglycerol level in mice. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12878451
|
Matias I et al. |
Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. |
2006 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:17011761
|
Iannotti FA et al. |
Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats. |
2013 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:23830028
|
Biernacki M et al. |
Hypertension and chronic inhibition of endocannabinoid degradation modify the endocannabinoid system and redox balance in rat heart and plasma. |
2018 |
Prostaglandins Other Lipid Mediat. |
pmid:30201316
|
Wang J and Ueda N |
Biology of endocannabinoid synthesis system. |
2009 |
Prostaglandins Other Lipid Mediat. |
pmid:19126434
|
Wang H et al. |
Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. |
2007 |
Prostaglandins Other Lipid Mediat. |
pmid:17259073
|
Fonseca BM et al. |
Endogenous cannabinoids revisited: a biochemistry perspective. |
2013 Apr-May |
Prostaglandins Other Lipid Mediat. |
pmid:23474290
|
Hillard CJ |
Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. |
2000 |
Prostaglandins Other Lipid Mediat. |
pmid:10785538
|
Di Marzo V et al. |
Cannabimimetic fatty acid derivatives in cancer and inflammation. |
2000 |
Prostaglandins Other Lipid Mediat. |
pmid:10785541
|
Kunos G et al. |
Cardiovascular effects of endocannabinoids--the plot thickens. |
2000 |
Prostaglandins Other Lipid Mediat. |
pmid:10785543
|
Szafran B et al. |
Lipopolysaccharide suppresses carboxylesterase 2g activity and 2-arachidonoylglycerol hydrolysis: A possible mechanism to regulate inflammation. |
2015 |
Prostaglandins Other Lipid Mediat. |
pmid:26403860
|
Basavarajappa BS |
Critical enzymes involved in endocannabinoid metabolism. |
2007 |
Protein Pept. Lett. |
pmid:17346227
|
Schalk-Hihi C et al. |
Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Ã… resolution. |
2011 |
Protein Sci. |
pmid:21308848
|
Coccaro EF et al. |
Circulating endocannabinoids and affect regulation in human subjects. |
2018 |
Psychoneuroendocrinology |
pmid:29627714
|
Heyman E et al. |
Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. |
2012 |
Psychoneuroendocrinology |
pmid:22029953
|
Atsak P et al. |
Glucocorticoid-endocannabinoid uncoupling mediates fear suppression deficits after early - Life stress. |
2018 |
Psychoneuroendocrinology |
pmid:29524763
|
Hill MN et al. |
Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. |
2009 |
Psychoneuroendocrinology |
pmid:19394765
|
Gray JM et al. |
Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. |
2016 |
Psychoneuroendocrinology |
pmid:26821211
|
Hill MN et al. |
Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. |
2013 |
Psychoneuroendocrinology |
pmid:24035186
|
Higgs S et al. |
Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. |
2003 |
Psychopharmacology (Berl.) |
pmid:12447606
|
Sustkova-Fiserova M et al. |
Ghrelin and endocannabinoids participation in morphine-induced effects in the rat nucleus accumbens. |
2016 |
Psychopharmacology (Berl.) |
pmid:26507196
|
Llorente-Berzal A et al. |
2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons. |
2015 |
Psychopharmacology (Berl.) |
pmid:25814137
|
Aliczki M et al. |
Involvement of 2-arachidonoylglycerol signaling in social challenge responding of male CD1 mice. |
2015 |
Psychopharmacology (Berl.) |
pmid:25547462
|
Limebeer CL et al. |
Attenuation of anticipatory nausea in a rat model of contextually elicited conditioned gaping by enhancement of the endocannabinoid system. |
2014 |
Psychopharmacology (Berl.) |
pmid:24043345
|
McReynolds JR et al. |
CB1 receptor antagonism blocks stress-potentiated reinstatement of cocaine seeking in rats. |
2016 |
Psychopharmacology (Berl.) |
pmid:26455361
|