2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Fuss J et al. | Masturbation to Orgasm Stimulates the Release of the Endocannabinoid 2-Arachidonoylglycerol in Humans. | 2017 | J Sex Med | pmid:29110806 |
Valastro C et al. | Characterization of endocannabinoids and related acylethanolamides in the synovial fluid of dogs with osteoarthritis: a pilot study. | 2017 | BMC Vet. Res. | pmid:29110674 |
Artegoitia VM et al. | Endocannabinoid concentrations in plasma during the finishing period are associated with feed efficiency and carcass composition of beef cattle. | 2017 | J. Anim. Sci. | pmid:29108057 |
Avraham Y et al. | 2-Arachidonoylglycerol as a possible treatment for anorexia nervosa in animal model in mice. | 2017 | Brain Res. | pmid:28606779 |
Vujic N et al. | Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice. | 2017 | Oncotarget | pmid:28380440 |
Brellenthin AG et al. | Endocannabinoid and Mood Responses to Exercise in Adults with Varying Activity Levels. | 2017 | Med Sci Sports Exerc | pmid:28319590 |
Almeida-Santos AF et al. | 2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. | 2017 | J. Psychopharmacol. (Oxford) | pmid:28440729 |
Soni N et al. | Anandamide and 2-AG are endogenously present within the laterodorsal tegmental nucleus: Functional implications for a role of eCBs in arousal. | 2017 | Brain Res. | pmid:28404451 |
Marchioni C et al. | A column switching ultrahigh-performance liquid chromatography-tandem mass spectrometry method to determine anandamide and 2-arachidonoylglycerol in plasma samples. | 2017 | Anal Bioanal Chem | pmid:28337517 |
Argueta DA and DiPatrizio NV | Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity. | 2017 | Physiol. Behav. | pmid:28065722 |
Thompson Z et al. | Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes. | 2017 | Physiol. Behav. | pmid:28017680 |
Kantae V et al. | Quantitative profiling of endocannabinoids and related -acylethanolamines in human CSF using nano LC-MS/MS. | 2017 | J. Lipid Res. | pmid:27999147 |
Tanaka M et al. | WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism. | 2017 | J Neuroinflammation | pmid:28086912 |
Wilkerson JL et al. | The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice. | 2017 | Neuropharmacology | pmid:27890602 |
Haruna T et al. | The Inhibitory Effect of S-777469, a Cannabinoid Type 2 Receptor Agonist, on Skin Inflammation in Mice. | 2017 | Pharmacology | pmid:28214870 |
Pagano E et al. | Pharmacological inhibition of MAGL attenuates experimental colon carcinogenesis. | 2017 | Pharmacol. Res. | pmid:28193521 |
Li B et al. | Endocannabinoid 2-arachidonoylglycerol protects inflammatory insults from sulfur dioxide inhalation via cannabinoid receptors in the brain. | 2017 | J Environ Sci (China) | pmid:28115138 |
Hassanzadeh P et al. | Application of carbon nanotubes as the carriers of the cannabinoid, 2-arachidonoylglycerol: Towards a novel treatment strategy in colitis. | 2017 | Life Sci. | pmid:27888115 |
Smaga I et al. | Changes in the Brain Endocannabinoid System in Rat Models of Depression. | 2017 | Neurotox Res | pmid:28247204 |
Quartu M et al. | Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion. | 2017 | Lipids Health Dis | pmid:28103941 |