| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperkinesis | D006948 | 11 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Encephalitis | D004660 | 15 associated lipids |
| Liver Cirrhosis, Alcoholic | D008104 | 17 associated lipids |
| Hypothermia | D007035 | 19 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Hypoxia-Ischemia, Brain | D020925 | 22 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Almeida-Santos AF et al. | 2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. | 2017 | J. Psychopharmacol. (Oxford) | pmid:28440729 |
| Thompson Z et al. | Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes. | 2017 | Physiol. Behav. | pmid:28017680 |
| Chen Y et al. | Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum. | 2016 May-Jun | eNeuro | pmid:27182552 |
| Zhang L et al. | Endocannabinoid 2-AG and intracellular cannabinoid receptors modulate a low-threshold calcium spike-induced slow depolarizing afterpotential in rat thalamic paraventricular nucleus neurons. | 2016 | Neuroscience | pmid:26924019 |
| Tomas-Roig J et al. | Social defeat leads to changes in the endocannabinoid system: An overexpression of calreticulin and motor impairment in mice. | 2016 | Behav. Brain Res. | pmid:26815100 |
| Siegmund SV et al. | Cyclooxygenase-2 contributes to the selective induction of cell death by the endocannabinoid 2-arachidonoyl glycerol in hepatic stellate cells. | 2016 | Biochem. Biophys. Res. Commun. | pmid:26801558 |
| Yi B et al. | Reductions in circulating endocannabinoid 2-arachidonoylglycerol levels in healthy human subjects exposed to chronic stressors. | 2016 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:26780604 |
| Sanchez AM et al. | Elevated Systemic Levels of Endocannabinoids and Related Mediators Across the Menstrual Cycle in Women With Endometriosis. | 2016 | Reprod Sci | pmid:26887427 |
| Doenni VM et al. | Deficient adolescent social behavior following early-life inflammation is ameliorated by augmentation of anandamide signaling. | 2016 | Brain Behav. Immun. | pmid:27453335 |
| Dong L et al. | Interactions of 2-O-arachidonylglycerol ether and ibuprofen with the allosteric and catalytic subunits of human COX-2. | 2016 | J. Lipid Res. | pmid:27059979 |
| Schlabritz-Loutsevitch N et al. | Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity. | 2016 | Med. Hypotheses | pmid:27959272 |
| Gamelin FX et al. | Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity. | 2016 | J. Physiol. Biochem. | pmid:26880264 |
| Monteleone AM et al. | Responses of peripheral endocannabinoids and endocannabinoid-related compounds to hedonic eating in obesity. | 2016 | Eur J Nutr | pmid:26759262 |
| Malek N et al. | The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain. | 2016 | Pharmacol. Res. | pmid:27326920 |
| Sharkey KA and Wiley JW | The Role of the Endocannabinoid System in the Brain-Gut Axis. | 2016 | Gastroenterology | pmid:27133395 |
| Sido JM et al. | Production of endocannabinoids by activated TÂ cells and BÂ cells modulates inflammation associated with delayed-type hypersensitivity. | 2016 | Eur. J. Immunol. | pmid:27064137 |
| Brose SA et al. | Brain 2-Arachidonoylglycerol Levels Are Dramatically and Rapidly Increased Under Acute Ischemia-Injury Which Is Prevented by Microwave Irradiation. | 2016 | Lipids | pmid:27021494 |
| Delgado-Peraza F et al. | Mechanisms of Biased β-Arrestin-Mediated Signaling Downstream from the Cannabinoid 1 Receptor. | 2016 | Mol. Pharmacol. | pmid:27009233 |
| Lim J et al. | Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats. | 2016 | Neuropsychopharmacology | pmid:26361059 |
| Stark DT and Caprioli J | Subcellular Localization of a 2-Arachidonoyl Glycerol Signaling Cassette in Retinal Ganglion Cell Axonal Growth In Vitro. | 2016 | Invest. Ophthalmol. Vis. Sci. | pmid:28002563 |