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A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease. |
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The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications. |
2005 |
J. Med. Chem. |
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Differential effects of endocannabinoids on [(3)H]-GABA uptake in the rat globus pallidus. |
2005 |
Exp. Neurol. |
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2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces rapid actin polymerization in HL-60 cells differentiated into macrophage-like cells. |
2005 |
Biochem. J. |
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An endocannabinoid mechanism for stress-induced analgesia. |
2005 |
Nature |
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Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine. |
2005 |
J. Immunol. |
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Effects of cannabinoids on colonic muscle contractility and tension in guinea pigs. |
2005 |
J Nippon Med Sch |
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Antifibrogenic role of the cannabinoid receptor CB2 in the liver. |
2005 |
Gastroenterology |
pmid:15765409
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Finding of endocannabinoids in human eye tissues: implications for glaucoma. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15823551
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Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. |
2005 |
J. Physiol. (Lond.) |
pmid:16179366
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Activation of the peripheral endocannabinoid system in human obesity. |
2005 |
Diabetes |
pmid:16186383
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Endocannabinoid identification in the brain: studies of breakdown lead to breakthrough, and there may be NO hope. |
2005 |
Sci. STKE |
pmid:16278487
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Maccarrone M et al. |
Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility. |
2005 |
Mol. Hum. Reprod. |
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Waterborne lead exposure affects brain endocannabinoid content in male but not female fathead minnows (Pimephales promelas). |
2005 |
Neurotoxicology |
pmid:15527869
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2005 |
J. Pharmacol. Exp. Ther. |
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Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: possible risk for autoimmune disorders. |
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J. Leukoc. Biol. |
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Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. |
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Mol. Pharmacol. |
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Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. |
2005 |
Nat. Neurosci. |
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2005 |
CMAJ |
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Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum. |
2005 |
J. Neurosci. |
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CB1 cannabinoid receptors are involved in neuroprotection via NF-kappa B inhibition. |
2005 |
J. Cereb. Blood Flow Metab. |
pmid:15729296
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Cyclooxygenase-2-specific inhibitor improves functional outcomes, provides neuroprotection, and reduces inflammation in a rat model of traumatic brain injury. |
2005 |
Neurosurgery |
pmid:15730585
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2-Arachidonoylglycerol stimulates activator protein-1-dependent transcriptional activity and enhances epidermal growth factor-induced cell transformation in JB6 P+ cells. |
2005 |
J. Biol. Chem. |
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Rouzer CA and Marnett LJ |
Glycerylprostaglandin synthesis by resident peritoneal macrophages in response to a zymosan stimulus. |
2005 |
J. Biol. Chem. |
pmid:15917246
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A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. |
2005 |
Biochem. Biophys. Res. Commun. |
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Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew. |
2005 |
Neuropharmacology |
pmid:15921709
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Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. |
2005 |
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Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. |
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Am. J. Physiol. Heart Circ. Physiol. |
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Endocannabinoids and liver disease--review. |
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Liver Int. |
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Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:16181610
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Therapeutic potential of the endocannabinoid system in the brain. |
2005 |
Mini Rev Med Chem |
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Coronary vasodilator effects of endogenous cannabinoids in vasopressin-preconstricted unpaced rat isolated hearts. |
2005 |
J. Cardiovasc. Pharmacol. |
pmid:16116341
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McPartland JM et al. |
Cannabimimetic effects of osteopathic manipulative treatment. |
2005 |
J Am Osteopath Assoc |
pmid:16118355
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The endocannabinoid arachidonyl ethanolamide (anandamide) increases pulmonary arterial pressure via cyclooxygenase-2 products in isolated rabbit lungs. |
2005 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:16055511
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2-Arachidonoylglycerol increases in ischemia-reperfusion injury of the rat liver. |
2005 Jan-Feb |
J Invest Surg |
pmid:15804949
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Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol. |
2006 |
J. Physiol. (Lond.) |
pmid:16973696
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Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. |
2006 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Effect of lipid rafts on Cb2 receptor signaling and 2-arachidonoyl-glycerol metabolism in human immune cells. |
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J. Immunol. |
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Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol. |
2006 |
Biochimie |
pmid:16949718
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2-Arachidonylglycerol acting on CB1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts. |
2006 |
J. Cardiovasc. Pharmacol. |
pmid:16775503
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Monoacylglycerol lipase inhibition by organophosphorus compounds leads to elevation of brain 2-arachidonoylglycerol and the associated hypomotility in mice. |
2006 |
Toxicol. Appl. Pharmacol. |
pmid:16310817
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Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels. |
2006 |
Cell. Mol. Life Sci. |
pmid:16732431
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The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. |
2006 |
Neurobiol. Dis. |
pmid:16364651
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Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE). |
2006 |
Bioorg. Med. Chem. |
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URB754 has no effect on the hydrolysis or signaling capacity of 2-AG in the rat brain. |
2006 |
Chem. Biol. |
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PGE2 glycerol ester, a COX-2 oxidative metabolite of 2-arachidonoyl glycerol, modulates inhibitory synaptic transmission in mouse hippocampal neurons. |
2006 |
J. Physiol. (Lond.) |
pmid:16484297
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Parkkari T et al. |
Alpha-methylated derivatives of 2-arachidonoyl glycerol: synthesis, CB1 receptor activity, and enzymatic stability. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16466915
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Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils. |
2006 |
J. Biol. Chem. |
pmid:16513651
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The synthetic cannabinoid WIN 55,212-2 increases COX-2 expression and PGE2 release in murine brain-derived endothelial cells following Theiler's virus infection. |
2006 |
Biochem. Pharmacol. |
pmid:16914119
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Blüher M et al. |
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity. |
2006 |
Diabetes |
pmid:17065342
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