| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acute Pain | D059787 | 3 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Richardson D et al. | Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry. | 2007 | Anal. Biochem. | pmid:17141174 |
| Bátkai S et al. | Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. | 2007 | FASEB J. | pmid:17327359 |
| Wang H et al. | Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17259073 |
| Sang N et al. | COX-2 oxidative metabolite of endocannabinoid 2-AG enhances excitatory glutamatergic synaptic transmission and induces neurotoxicity. | 2007 | J. Neurochem. | pmid:17539917 |
| Jung KM et al. | A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. | 2007 | Mol. Pharmacol. | pmid:17584991 |
| Siegmund SV et al. | The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species. | 2007 | FASEB J. | pmid:17440119 |
| Uchigashima M et al. | Subcellular arrangement of molecules for 2-arachidonoyl-glycerol-mediated retrograde signaling and its physiological contribution to synaptic modulation in the striatum. | 2007 | J. Neurosci. | pmid:17409230 |
| Lafourcade M et al. | Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex. | 2007 | PLoS ONE | pmid:17684555 |
| Gokoh M et al. | 2-Arachidonoylglycerol enhances the phagocytosis of opsonized zymosan by HL-60 cells differentiated into macrophage-like cells. | 2007 | Biol. Pharm. Bull. | pmid:17603153 |
| Sarchielli P et al. | Endocannabinoids in chronic migraine: CSF findings suggest a system failure. | 2007 | Neuropsychopharmacology | pmid:17119542 |
| Degn M et al. | Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice. | 2007 | J. Neurochem. | pmid:17868306 |
| Sugiura T | [2-Arachidonoylglycerol: an endogenous cannabinoid receptor ligand]. | 2007 | Seikagaku | pmid:17763698 |
| He F et al. | Involvement of the 90-kDa heat shock protein (Hsp-90) in CB2 cannabinoid receptor-mediated cell migration: a new role of Hsp-90 in migration signaling of a G protein-coupled receptor. | 2007 | Mol. Pharmacol. | pmid:17698952 |
| Rossi G et al. | Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. | 2007 | Endocrinology | pmid:17110429 |
| Deshpande LS et al. | Endocannabinoids block status epilepticus in cultured hippocampal neurons. | 2007 | Eur. J. Pharmacol. | pmid:17174949 |
| Côté M et al. | Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. | 2007 | Int J Obes (Lond) | pmid:17224929 |
| DeMorrow S et al. | Opposing actions of endocannabinoids on cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid rafts. | 2007 | J. Biol. Chem. | pmid:17329257 |
| Kreutz S et al. | Cannabinoids and neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. | 2007 | Exp. Neurol. | pmid:17010339 |
| Straiker A and Mackie K | Metabotropic suppression of excitation in murine autaptic hippocampal neurons. | 2007 | J. Physiol. (Lond.) | pmid:17110416 |
| Blankman JL et al. | A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. | 2007 | Chem. Biol. | pmid:18096503 |