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The endocannabinoid 2-arachidonoylglycerol activates human platelets through non-CB1/CB2 receptors. |
2008 |
J. Thromb. Haemost. |
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Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18657971
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Llorente R et al. |
Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid system. |
2008 |
Dev Neurobiol |
pmid:18666205
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Ellgren M et al. |
Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. |
2008 |
Eur Neuropsychopharmacol |
pmid:18674887
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Fowler CJ and Ghafouri N |
Does the hydrolysis of 2-arachidonoylglycerol regulate its cellular uptake? |
2008 |
Pharmacol. Res. |
pmid:18675915
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Burston JJ et al. |
N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:18682568
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Nomura DK et al. |
Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18752948
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Placzek EA et al. |
Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. |
2008 |
Neuropharmacology |
pmid:18760289
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Avraham Y et al. |
2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist, in various rat tissues during the evolution of experimental cholestatic liver disease. |
2008 Jul-Aug |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:18771906
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Placzek EA et al. |
Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. |
2008 |
J. Neurochem. |
pmid:18778304
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Fowler CJ |
"The tools of the trade"--an overview of the pharmacology of the endocannabinoid system. |
2008 |
Curr. Pharm. Des. |
pmid:18781976
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Ruby MA et al. |
Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18794527
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DiPatrizio NV and Simansky KJ |
Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats. |
2008 |
J. Neurosci. |
pmid:18815256
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Bajo M et al. |
Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. |
2009 |
J. Neurosci. Res. |
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Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. |
2009 |
J. Mol. Med. |
pmid:18820887
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Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism. |
2008 |
J. Med. Chem. |
pmid:18831576
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2-Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal-cannabidiol-sensitive receptors on microglial cells. |
2009 |
Glia |
pmid:18837048
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Garcia-Ovejero D et al. |
The endocannabinoid system is modulated in response to spinal cord injury in rats. |
2009 |
Neurobiol. Dis. |
pmid:18930143
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Lu TS et al. |
Cannabinoids inhibit HIV-1 Gp120-mediated insults in brain microvascular endothelial cells. |
2008 |
J. Immunol. |
pmid:18941231
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Di Marzo V et al. |
Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. |
2009 |
Diabetologia |
pmid:18972095
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Hill MN et al. |
Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. |
2008 |
J Neural Transm |
pmid:18974922
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Bisogno T et al. |
Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo. |
2009 |
Biochim. Biophys. Acta |
pmid:19027877
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Long JZ et al. |
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. |
2009 |
Nat. Chem. Biol. |
pmid:19029917
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Vignali M et al. |
The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. |
2009 |
Glia |
pmid:19031444
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Lehtonen M et al. |
Mass-spectrometric identification of anandamide and 2-arachidonoylglycerol in nematodes. |
2008 |
Chem. Biodivers. |
pmid:19035572
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Marinelli S et al. |
The endocannabinoid 2-arachidonoylglycerol is responsible for the slow self-inhibition in neocortical interneurons. |
2008 |
J. Neurosci. |
pmid:19074027
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Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. |
2009 |
Cardiovasc. Res. |
pmid:19074161
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Wang J and Ueda N |
Biology of endocannabinoid synthesis system. |
2009 |
Prostaglandins Other Lipid Mediat. |
pmid:19126434
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Koppel J et al. |
Endocannabinoids in Alzheimer's disease and their impact on normative cognitive performance: a case-control and cohort study. |
2009 |
Lipids Health Dis |
pmid:19144193
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Schlosburg JE et al. |
Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. |
2009 |
AAPS J |
pmid:19184452
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Maccarrone M et al. |
Lipid rafts regulate 2-arachidonoylglycerol metabolism and physiological activity in the striatum. |
2009 |
J. Neurochem. |
pmid:19187444
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Bisogno T et al. |
Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol. |
2009 |
ChemMedChem |
pmid:19266526
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The role of the pancreatic endocannabinoid system in glucose metabolism. |
2009 |
Best Pract. Res. Clin. Endocrinol. Metab. |
pmid:19285263
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Sugiura T |
Physiological roles of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. |
2009 Jan-Feb |
Biofactors |
pmid:19319851
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Urbanski MJ et al. |
Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling. |
2009 |
Synapse |
pmid:19347961
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Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. |
2009 |
Br. J. Pharmacol. |
pmid:19371345
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Yates ML and Barker EL |
Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. |
2009 |
Mol. Pharmacol. |
pmid:19389920
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Hill MN et al. |
Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. |
2009 |
Psychoneuroendocrinology |
pmid:19394765
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F2-isoprostanes and 2-arachidonylglycerol as biomarkers of lipid peroxidation in pigs with hepatic ischemia/reperfusion injury. |
2010 |
J. Surg. Res. |
pmid:19439322
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Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. |
2009 |
Eur. J. Neurosci. |
pmid:19453631
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Straiker A and Mackie K |
Cannabinoid signaling in inhibitory autaptic hippocampal neurons. |
2009 |
Neuroscience |
pmid:19501632
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Kinsey SG et al. |
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. |
2009 |
J. Pharmacol. Exp. Ther. |
pmid:19502530
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Greco R et al. |
Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of rat. |
2010 |
Cephalalgia |
pmid:19515121
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Dowie MJ et al. |
Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. |
2009 |
Neuroscience |
pmid:19524019
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Maeda N et al. |
Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. |
2009 |
Fundam Clin Pharmacol |
pmid:19527302
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Grimaldi P et al. |
The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19541620
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Bowman AL and Makriyannis A |
Refined homology model of monoacylglycerol lipase: toward a selective inhibitor. |
2009 |
J. Comput. Aided Mol. Des. |
pmid:19543978
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Batetta B et al. |
Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. |
2009 |
J. Nutr. |
pmid:19549757
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Guasti L et al. |
Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. |
2009 |
Mol Pain |
pmid:19570201
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Wakley AA and Rasmussen EB |
Effects of cannabinoid drugs on the reinforcing properties of food in gestationally undernourished rats. |
2009 |
Pharmacol. Biochem. Behav. |
pmid:19602424
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