| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hepatic Encephalopathy | D006501 | 9 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Starvation | D013217 | 47 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Covey DP et al. | Inhibition of endocannabinoid degradation rectifies motivational and dopaminergic deficits in the Q175 mouse model of Huntington's disease. | 2018 | Neuropsychopharmacology | pmid:29925886 |
| Ratano P et al. | Pharmacological inhibition of 2-arachidonoilglycerol hydrolysis enhances memory consolidation in rats through CB2 receptor activation and mTOR signaling modulation. | 2018 | Neuropharmacology | pmid:29842858 |
| Jehle J et al. | Elevated levels of 2-arachidonoylglycerol promote atherogenesis in ApoE-/- mice. | 2018 | PLoS ONE | pmid:29813086 |
| Forner-Piquer I et al. | Disruption of the gonadal endocannabinoid system in zebrafish exposed to diisononyl phthalate. | 2018 | Environ. Pollut. | pmid:29793103 |
| Baggelaar MP et al. | 2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain. | 2018 | Prog. Lipid Res. | pmid:29751000 |
| Coccaro EF et al. | Circulating endocannabinoids and affect regulation in human subjects. | 2018 | Psychoneuroendocrinology | pmid:29627714 |
| Nagappan A et al. | Protective Effects of Gomisin N against Hepatic Cannabinoid Type 1 Receptor-Induced Insulin Resistance and Gluconeogenesis. | 2018 | Int J Mol Sci | pmid:29570673 |
| Signorello MG and Leoncini G | Activation of CaMKKβ/AMPKα pathway by 2-AG in human platelets. | 2018 | J. Cell. Biochem. | pmid:28661046 |
| Köse S et al. | Human bone marrow mesenchymal stem cells secrete endocannabinoids that stimulate in vitro hematopoietic stem cell migration effectively comparable to beta-adrenergic stimulation. | 2018 | Exp. Hematol. | pmid:29030083 |
| Kranaster L et al. | Electroconvulsive therapy enhances endocannabinoids in the cerebrospinal fluid of patients with major depression: a preliminary prospective study. | 2017 | Eur Arch Psychiatry Clin Neurosci | pmid:28342110 |
| Dotsey E et al. | Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice. | 2017 | Sci Rep | pmid:28209996 |
| Karwad MA et al. | The role of CB in intestinal permeability and inflammation. | 2017 | FASEB J. | pmid:28404744 |
| Cui N et al. | Restored Plasma Anandamide and Endometrial Expression of Fatty Acid Amide Hydrolase in Women With Polycystic Ovary Syndrome by the Combination Use of Diane-35 and Metformin. | 2017 | Clin Ther | pmid:28291580 |
| Gantz SC and Bean BP | Cell-Autonomous Excitation of Midbrain Dopamine Neurons by Endocannabinoid-Dependent Lipid Signaling. | 2017 | Neuron | pmid:28262417 |
| Abed SM et al. | Synthesis of 1,3-dioleoyl-2-arachidonoylglycerol-rich structured lipids by lipase-catalyzed acidolysis of microbial oil from Mortierella alpina. | 2017 | Bioresour. Technol. | pmid:28688328 |
| Karpińska O et al. | Activation of CB receptors by 2-arachidonoylglycerol attenuates vasoconstriction induced by U46619 and angiotensin II in human and rat pulmonary arteries. | 2017 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:28356298 |
| Chanda D et al. | 2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes. | 2017 | J. Biol. Chem. | pmid:28320859 |
| Bakas T et al. | The direct actions of cannabidiol and 2-arachidonoyl glycerol at GABA receptors. | 2017 | Pharmacol. Res. | pmid:28249817 |
| Haruna T et al. | The Inhibitory Effect of S-777469, a Cannabinoid Type 2 Receptor Agonist, on Skin Inflammation in Mice. | 2017 | Pharmacology | pmid:28214870 |
| Smaga I et al. | Changes in the Brain Endocannabinoid System in Rat Models of Depression. | 2017 | Neurotox Res | pmid:28247204 |