Nomura DK et al. |
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation. |
2011 |
Science |
pmid:22021672
|
Muppidi JR et al. |
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. |
2011 |
J. Exp. Med. |
pmid:21875957
|
Zhang L et al. |
Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase. |
2011 |
PLoS ONE |
pmid:21305054
|
Schalk-Hihi C et al. |
Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Ã… resolution. |
2011 |
Protein Sci. |
pmid:21308848
|
Du H et al. |
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ. |
2011 |
Br. J. Pharmacol. |
pmid:21501147
|
Raman P et al. |
15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma. |
2011 |
Mol. Pharmacol. |
pmid:21511917
|
Bari M et al. |
Characterization of the endocannabinoid system in mouse embryonic stem cells. |
2011 |
Stem Cells Dev. |
pmid:20446814
|
Higuchi S et al. |
Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors. |
2011 |
Behav. Brain Res. |
pmid:20817042
|
Ludányi A et al. |
Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. |
2011 |
Neuroscience |
pmid:21035522
|
Hofmann ME et al. |
Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. |
2011 |
J. Physiol. (Lond.) |
pmid:21646412
|
MartÃn-Couce L et al. |
Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors. |
2011 |
J. Med. Chem. |
pmid:21675776
|
Chanda D et al. |
Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes. |
2011 |
J. Biol. Chem. |
pmid:21693703
|
Busquets-Garcia A et al. |
Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. |
2011 |
Biol. Psychiatry |
pmid:21684528
|
Signorello MG et al. |
Activation of human platelets by 2-arachidonoylglycerol: role of PKC in NO/cGMP pathway modulation. |
2011 |
Curr Neurovasc Res |
pmid:21675954
|
Sarmad S et al. |
Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. |
2011 |
J. Neurochem. |
pmid:21375532
|
Marrs WR et al. |
Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons. |
2011 |
J. Biol. Chem. |
pmid:21665953
|
Gantayet A et al. |
Endocannabinoids and diacylglycerol kinase activity. |
2011 |
Biochim. Biophys. Acta |
pmid:21194521
|
Howlett AC et al. |
Endocannabinoid tone versus constitutive activity of cannabinoid receptors. |
2011 |
Br. J. Pharmacol. |
pmid:21545414
|
Carr RL et al. |
Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. |
2011 |
Toxicol. Sci. |
pmid:21507991
|
Chiba T et al. |
A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. |
2011 |
J. Pharm. Pharmacol. |
pmid:21492165
|
Chen X et al. |
Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults. |
2011 |
Neuroscience |
pmid:21256197
|
Yoshida T et al. |
Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21282604
|
Liao HT et al. |
Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition. |
2011 |
Br. J. Pharmacol. |
pmid:21232043
|
Soderstrom K et al. |
Cannabinoid exposure during zebra finch sensorimotor vocal learning persistently alters expression of endocannabinoid signaling elements and acute agonist responsiveness. |
2011 |
BMC Neurosci |
pmid:21211022
|
De Petrocellis L et al. |
Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. |
2011 |
Br. J. Pharmacol. |
pmid:21175579
|
Petrosino S et al. |
Alteration of the endocannabinoid system in mouse brain during prion disease. |
2011 |
Neuroscience |
pmid:21195746
|
Jumpertz R et al. |
Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. |
2011 |
J. Clin. Endocrinol. Metab. |
pmid:21177788
|
Sciolino NR et al. |
Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats. |
2011 |
Pharmacol. Res. |
pmid:21600985
|
Uchigashima M et al. |
Molecular and morphological configuration for 2-arachidonoylglycerol-mediated retrograde signaling at mossy cell-granule cell synapses in the dentate gyrus. |
2011 |
J. Neurosci. |
pmid:21613483
|
Di Marzo V |
Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. |
2011 |
Nat. Neurosci. |
pmid:21187849
|
Alhouayek M et al. |
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. |
2011 |
FASEB J. |
pmid:21551239
|
Justinová Z et al. |
The endogenous cannabinoid 2-arachidonoylglycerol is intravenously self-administered by squirrel monkeys. |
2011 |
J. Neurosci. |
pmid:21562266
|
Guindon J et al. |
Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. |
2011 |
Br. J. Pharmacol. |
pmid:21198549
|
Borges BC et al. |
Leptin resistance and desensitization of hypophagia during prolonged inflammatory challenge. |
2011 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:21343543
|
Shekhar C |
Mixed signals: cannabinoid system offers new therapeutic possibilities as well as challenges. |
2011 |
Chem. Biol. |
pmid:21609833
|
Quercioli A et al. |
Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. |
2011 |
Eur. Heart J. |
pmid:21303779
|
Brizzi A et al. |
Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. |
2011 |
J. Med. Chem. |
pmid:22044209
|
Chouinard F et al. |
The endocannabinoid 2-arachidonoyl-glycerol activates human neutrophils: critical role of its hydrolysis and de novo leukotriene B4 biosynthesis. |
2011 |
J. Immunol. |
pmid:21278347
|
Khasabova IA et al. |
Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. |
2011 |
Pharmacol. Res. |
pmid:21440630
|
Catanzaro G et al. |
Effect of capacitation on the endocannabinoid system of mouse sperm. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21723369
|
Hoot MR et al. |
Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. |
2010 |
Brain Res. |
pmid:20380816
|
Musella A et al. |
Transient receptor potential vanilloid 1 channels control acetylcholine/2-arachidonoylglicerol coupling in the striatum. |
2010 |
Neuroscience |
pmid:20219639
|
Placzek EA et al. |
Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide). |
2010 |
J Pharm Biomed Anal |
pmid:20417049
|
Massa F et al. |
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. |
2010 |
J. Neurosci. |
pmid:20445053
|
Bardell TK and Barker EL |
Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. |
2010 |
Neurochem. Int. |
pmid:20466028
|
Muccioli GG |
Endocannabinoid biosynthesis and inactivation, from simple to complex. |
2010 |
Drug Discov. Today |
pmid:20304091
|
Kozono S et al. |
Involvement of the endocannabinoid system in periodontal healing. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20233580
|
Jyotaki M et al. |
Modulation of sweet taste sensitivity by orexigenic and anorexigenic factors. |
2010 |
Endocr. J. |
pmid:20431269
|
Mukhopadhyay B et al. |
Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma. |
2010 |
J. Biol. Chem. |
pmid:20410309
|
Maccarrone M |
Endocannabinoid-binding receptors: old friends and new comers. |
2010 |
Curr. Med. Chem. |
pmid:20441559
|