| MeSH term | MeSH ID | Detail |
|---|---|---|
| Liver Cirrhosis, Alcoholic | D008104 | 17 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gurwitz D and Kloog Y | Do endogenous cannabinoids contribute to HIV-mediated immune failure? | 1998 | Mol Med Today | pmid:9612798 |
| Di Marzo V et al. | Trick or treat from food endocannabinoids? | 1998 | Nature | pmid:9872309 |
| Kondo S et al. | 2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through CA2+-dependent and -independent mechanisms. | 1998 | FEBS Lett. | pmid:9650580 |
| Ben-Shabat S et al. | An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. | 1998 | Eur. J. Pharmacol. | pmid:9721036 |
| Mechoulam R et al. | Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid. | 1998 | Eur. J. Pharmacol. | pmid:9865537 |
| Piomelli D et al. | Structural determinants for recognition and translocation by the anandamide transporter. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10318965 |
| Di Marzo V et al. | Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments. | 1999 | Lipids | pmid:10419192 |
| Giuffrida A et al. | Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. | 1999 | Nat. Neurosci. | pmid:10204543 |
| Wagner JA et al. | Mesenteric vasodilation mediated by endothelial anandamide receptors. | 1999 | Hypertension | pmid:9931142 |
| Huang SM et al. | Liquid chromatographic-mass spectrometric measurement of the endogenous cannabinoid 2-arachidonylglycerol in the spinal cord and peripheral nervous system. | 1999 | Zhongguo Yao Li Xue Bao | pmid:11189199 |