| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuromyelitis Optica | D009471 | 2 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Midtbø LK et al. | Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice. | 2015 | J. Nutr. Biochem. | pmid:25776459 |
| Niki M et al. | Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice. | 2015 | J. Physiol. (Lond.) | pmid:25728242 |
| Bashashati M et al. | Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation. | 2015 | Br. J. Pharmacol. | pmid:25684407 |
| Schaich CL et al. | Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity. | 2015 | J. Cardiovasc. Pharmacol. | pmid:25636077 |
| Lecru L et al. | Cannabinoid receptor 1 is a major mediator of renal fibrosis. | 2015 | Kidney Int. | pmid:25760323 |
| Mann A et al. | Palmitoyl Serine: An Endogenous Neuroprotective Endocannabinoid-Like Entity After Traumatic Brain Injury. | 2015 | J Neuroimmune Pharmacol | pmid:25721934 |
| Marcaggi P | Cerebellar endocannabinoids: retrograde signaling from purkinje cells. | 2015 | Cerebellum | pmid:25520276 |
| Szekeres M et al. | Endocannabinoid-mediated modulation of Gq/11 protein-coupled receptor signaling-induced vasoconstriction and hypertension. | 2015 | Mol. Cell. Endocrinol. | pmid:25595485 |
| Walentiny DM et al. | Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice. | 2015 | Neuropharmacology | pmid:25698527 |
| Monteleone AM et al. | Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa. | 2015 | Am. J. Clin. Nutr. | pmid:25646322 |
| Gaskari SA et al. | Blunted cardiac response to hemorrhage in cirrhotic rats is mediated by local macrophage-released endocannabinoids. | 2015 | J. Hepatol. | pmid:25640062 |
| Pisanti S et al. | Anandamide drives cell cycle progression through CB1 receptors in a rat model of synchronized liver regeneration. | 2015 | J. Cell. Physiol. | pmid:25684344 |
| Aliczki M et al. | Involvement of 2-arachidonoylglycerol signaling in social challenge responding of male CD1 mice. | 2015 | Psychopharmacology (Berl.) | pmid:25547462 |
| Urquhart P et al. | Endocannabinoids and their oxygenation by cyclo-oxygenases, lipoxygenases and other oxygenases. | 2015 | Biochim. Biophys. Acta | pmid:25543004 |
| Wollank Y et al. | Inhibition of FAAH confers increased stem cell migration via PPARα. | 2015 | J. Lipid Res. | pmid:26263913 |
| Szafran B et al. | Lipopolysaccharide suppresses carboxylesterase 2g activity and 2-arachidonoylglycerol hydrolysis: A possible mechanism to regulate inflammation. | 2015 | Prostaglandins Other Lipid Mediat. | pmid:26403860 |
| Mitchener MM et al. | Competition and allostery govern substrate selectivity of cyclooxygenase-2. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26392530 |
| Wang H et al. | Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area. | 2015 | Cell Rep | pmid:26365195 |
| Ho WS et al. | Role of endothelial TRPV4 channels in vascular actions of the endocannabinoid, 2-arachidonoylglycerol. | 2015 | Br. J. Pharmacol. | pmid:26294342 |
| DiPatrizio NV et al. | Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways. | 2015 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:26290104 |