| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperkinesis | D006948 | 11 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Hypothermia | D007035 | 19 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Head Injuries, Closed | D016489 | 5 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Encephalitis | D004660 | 15 associated lipids |
| Memory Disorders | D008569 | 33 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Grabner GF et al. | Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation. | 2016 | J. Biol. Chem. | pmid:26565024 |
| Mann A et al. | Are the endocannabinoid-like compounds N-acyl aminoacids neuroprotective after traumatic brain injury? | 2016 | J Basic Clin Physiol Pharmacol | pmid:26565551 |
| Vujic N et al. | Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice. | 2016 | Atherosclerosis | pmid:26584135 |
| Hanlon EC et al. | Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol. | 2016 | Sleep | pmid:26612385 |
| Yang W et al. | Cannabinoid receptor agonists modulate calcium channels in rat retinal Müller cells. | 2016 | Neuroscience | pmid:26621126 |
| Gobira PH et al. | Role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey. | 2016 | Eur Neuropsychopharmacol | pmid:26628106 |
| Carr RL et al. | Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. | 2017 | Neurotoxicology | pmid:26642910 |
| Wills KL et al. | Double Dissociation of Monoacylglycerol Lipase Inhibition and CB1 Antagonism in the Central Amygdala, Basolateral Amygdala, and the Interoceptive Insular Cortex on the Affective Properties of Acute Naloxone-Precipitated Morphine Withdrawal in Rats. | 2016 | Neuropsychopharmacology | pmid:26647976 |
| Ogasawara D et al. | Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26668358 |
| Lu HC and Mackie K | An Introduction to the Endogenous Cannabinoid System. | 2016 | Biol. Psychiatry | pmid:26698193 |
| Costa MA et al. | The endocannabinoid 2-arachidonoylglycerol dysregulates the synthesis of proteins by the human syncytiotrophoblast. | 2016 | Biochim. Biophys. Acta | pmid:26698196 |
| González-Mariscal I et al. | Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice. | 2016 | Mol. Cell. Endocrinol. | pmid:26724516 |
| Buczynski MW et al. | Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26755579 |
| Monteleone AM et al. | Responses of peripheral endocannabinoids and endocannabinoid-related compounds to hedonic eating in obesity. | 2016 | Eur J Nutr | pmid:26759262 |
| Yi B et al. | Reductions in circulating endocannabinoid 2-arachidonoylglycerol levels in healthy human subjects exposed to chronic stressors. | 2016 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:26780604 |
| Aso C et al. | Protein purification and cloning of diacylglycerol lipase from rat brain. | 2016 | J. Biochem. | pmid:26790472 |
| Wilkerson JL et al. | The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model. | 2016 | J. Pharmacol. Exp. Ther. | pmid:26791602 |
| Siegmund SV et al. | Cyclooxygenase-2 contributes to the selective induction of cell death by the endocannabinoid 2-arachidonoyl glycerol in hepatic stellate cells. | 2016 | Biochem. Biophys. Res. Commun. | pmid:26801558 |
| Tomas-Roig J et al. | Social defeat leads to changes in the endocannabinoid system: An overexpression of calreticulin and motor impairment in mice. | 2016 | Behav. Brain Res. | pmid:26815100 |
| Gray JM et al. | Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. | 2016 | Psychoneuroendocrinology | pmid:26821211 |