| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperkinesis | D006948 | 11 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Hypothermia | D007035 | 19 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Head Injuries, Closed | D016489 | 5 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Encephalitis | D004660 | 15 associated lipids |
| Memory Disorders | D008569 | 33 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Karsak M et al. | Attenuation of allergic contact dermatitis through the endocannabinoid system. | 2007 | Science | pmid:17556587 |
| Nomura DK et al. | Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation. | 2011 | Science | pmid:22021672 |
| Stella N | Cell biology. Anatomy of prostaglandin signals. | 2011 | Science | pmid:22076368 |
| Mechoulam R and Lichtman AH | Neuroscience. Stout guards of the central nervous system. | 2003 | Science | pmid:14526067 |
| Miller MR et al. | Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone. | 2016 | Science | pmid:26989199 |
| Sugiura T | [2-Arachidonoylglycerol: an endogenous cannabinoid receptor ligand]. | 2007 | Seikagaku | pmid:17763698 |
| Hillard CJ | Stress regulates endocannabinoid-CB1 receptor signaling. | 2014 | Semin. Immunol. | pmid:24882055 |
| Wang SL et al. | [Cannabinoid receptor system regulates ion channels and synaptic transmission in retinal cells]. | 2017 | Sheng Li Xue Bao | pmid:29063116 |
| Motobe T et al. | Endogenous cannabinoids are candidates for lipid mediators of bone cement implantation syndrome. | 2004 | Shock | pmid:14676677 |
| Hanlon EC et al. | Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol. | 2016 | Sleep | pmid:26612385 |
| Bari M et al. | Characterization of the endocannabinoid system in mouse embryonic stem cells. | 2011 | Stem Cells Dev. | pmid:20446814 |
| Wingenfeld K et al. | Reduced levels of the endocannabinoid arachidonylethanolamide (AEA) in hair in patients with borderline personality disorder - a pilot study. | 2018 | Stress | pmid:29546791 |
| Urbanski MJ et al. | Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling. | 2009 | Synapse | pmid:19347961 |
| Sugiura T et al. | [2-Arachidonoylglycerol: an endogenous cannabinoid receptor agonist]. | 1999 | Tanpakushitsu Kakusan Koso | pmid:10396990 |
| Shiga N et al. | Elimination of 2-arachidonoylglycerol action by direct hemoperfusion through immobilized polymyxin B fibers: an experimental study in conscious guinea pigs. | 2006 | Ther Apher Dial | pmid:17199882 |
| Krumbholz A et al. | Diagnostic value of concentration profiles of glucocorticosteroids and endocannabinoids in hair. | 2013 | Ther Drug Monit | pmid:23942543 |
| Maccarrone M et al. | Activation of human platelets by 2-arachidonoylglycerol is enhanced by serotonin. | 2003 | Thromb. Haemost. | pmid:12574815 |
| Malorni W et al. | Morphological evidence that 2-arachidonoylglycerol is a true agonist of human platelets. | 2004 | Thromb. Haemost. | pmid:15543349 |
| Descalzi F et al. | Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism. | 2013 | Tissue Eng Part A | pmid:23578218 |
| Kondakala S et al. | Effects of acute exposure to chlorpyrifos on cholinergic and non-cholinergic targets in normal and high-fat fed male C57BL/6J mice. | 2017 | Toxicol. Appl. Pharmacol. | pmid:29097212 |