MeSH term | MeSH ID | Detail |
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Ganglion Cysts | D045888 | 1 associated lipids |
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Yi B et al. | Reductions in circulating endocannabinoid 2-arachidonoylglycerol levels in healthy human subjects exposed to chronic stressors. | 2016 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:26780604 |
Bystrowska B et al. | Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. | 2014 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:24334211 |
Baggelaar MP et al. | 2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain. | 2018 | Prog. Lipid Res. | pmid:29751000 |
Iannotti FA et al. | Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders. | 2016 | Prog. Lipid Res. | pmid:26965148 |
Sugiura T et al. | Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. | 2006 | Prog. Lipid Res. | pmid:16678907 |
Calignano A et al. | A role for the endogenous cannabinoid system in the peripheral control of pain initiation. | 2000 | Prog. Brain Res. | pmid:11098711 |
Chicca A et al. | Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:28584105 |
Morena M et al. | Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25489086 |
Iannotti FA et al. | The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24927567 |
Witting A et al. | P2X7 receptors control 2-arachidonoylglycerol production by microglial cells. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:14976257 |