Ryberg E et al. |
The orphan receptor GPR55 is a novel cannabinoid receptor. |
2007 |
Br. J. Pharmacol. |
pmid:17876302
|
Sakamoto Y et al. |
Clinical responses and improvement of some laboratory parameters following polymyxin B-immobilized fiber treatment in septic shock. |
2007 Sep-Oct |
ASAIO J. |
pmid:17885340
|
Duan Y et al. |
Inhibition of [3H]batrachotoxinin A-20alpha-benzoate binding to sodium channels and sodium channel function by endocannabinoids. |
2008 |
Neurochem. Int. |
pmid:17888543
|
Hillard CJ et al. |
Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. |
2007 |
Br. J. Pharmacol. |
pmid:17891162
|
Opitz CA et al. |
Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells. |
2007 |
FEBS Lett. |
pmid:17904123
|
Shiratsuchi A et al. |
Involvement of cannabinoid receptor CB2 in dectin-1-mediated macrophage phagocytosis. |
2008 |
Immunol. Cell Biol. |
pmid:17909562
|
Tanikawa T et al. |
Induction of preferential chemotaxis of unstimulated B-lymphocytes by 2-arachidonoylglycerol in immunized mice. |
2007 |
Microbiol. Immunol. |
pmid:17951991
|
Rimmerman N et al. |
Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line. |
2008 |
Br. J. Pharmacol. |
pmid:17965731
|
Mukhopadhyay S and Tulis DA |
Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. |
2007 |
Cardiovasc Hematol Agents Med Chem |
pmid:17979695
|
Dainese E et al. |
Modulation of the endocannabinoid system by lipid rafts. |
2007 |
Curr. Med. Chem. |
pmid:17979719
|
Muccioli GG and Stella N |
An optimized GC-MS method detects nanomolar amounts of anandamide in mouse brain. |
2008 |
Anal. Biochem. |
pmid:17981259
|
Thiemann G et al. |
The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization. |
2008 |
Behav. Brain Res. |
pmid:17988751
|
Béquet F et al. |
CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. |
2007 |
Eur. J. Neurosci. |
pmid:18052990
|
Hill MN et al. |
Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus. |
2008 |
Hippocampus |
pmid:18058925
|
Adermark L and Lovinger DM |
Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18077376
|
Marrs W and Stella N |
2-AG + 2 new players = forecast for therapeutic advances. |
2007 |
Chem. Biol. |
pmid:18096497
|
Imming P |
Fatty pain cures. |
2007 |
Chem. Biol. |
pmid:18096498
|
Blankman JL et al. |
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. |
2007 |
Chem. Biol. |
pmid:18096503
|
King AR et al. |
URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. |
2007 |
Chem. Biol. |
pmid:18096504
|
Maccarrone M et al. |
Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum. |
2008 |
Nat. Neurosci. |
pmid:18204441
|
Shimizu T and Yokotani K |
Bidirectional roles of the brain 2-arachidonoyl-sn-glycerol in the centrally administered vasopressin-induced adrenomedullary outflow in rats. |
2008 |
Eur. J. Pharmacol. |
pmid:18234185
|
Starowicz KM et al. |
Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet. |
2008 |
Obesity (Silver Spring) |
pmid:18239598
|
Guindon J and Hohmann AG |
A physiological role for endocannabinoid-derived products of cyclooxygenase-2-mediated oxidative metabolism. |
2008 |
Br. J. Pharmacol. |
pmid:18297102
|
Hu SS et al. |
Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity. |
2008 |
Br. J. Pharmacol. |
pmid:18297109
|
Oláh M et al. |
The role of endocannabinoids in the regulation of luteinizing hormone and prolactin release. Differences between the effects of AEA and 2AG. |
2008 |
Mol. Cell. Endocrinol. |
pmid:18308464
|
Hill MN et al. |
Serum endocannabinoid content is altered in females with depressive disorders: a preliminary report. |
2008 |
Pharmacopsychiatry |
pmid:18311684
|
Friedman SL and Nieto N |
Cannabinoids provoke alcoholic steatosis through a conspiracy of neighbors. |
2008 |
Cell Metab. |
pmid:18316020
|
Jeong WI et al. |
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. |
2008 |
Cell Metab. |
pmid:18316028
|
Vellani V et al. |
Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin. |
2008 |
Neuropharmacology |
pmid:18329052
|
Palkovits M et al. |
Regional distribution and effects of postmortal delay on endocannabinoid content of the human brain. |
2008 |
Neuroscience |
pmid:18343585
|
Engeli S et al. |
Peripheral endocannabinoid system activity in patients treated with sibutramine. |
2008 |
Obesity (Silver Spring) |
pmid:18356837
|
Rubio M et al. |
CB1 receptor blockade reduces the anxiogenic-like response and ameliorates the neurochemical imbalances associated with alcohol withdrawal in rats. |
2008 |
Neuropharmacology |
pmid:18371990
|
Awumey EM et al. |
Cytochrome P-450 metabolites of 2-arachidonoylglycerol play a role in Ca2+-induced relaxation of rat mesenteric arteries. |
2008 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:18375719
|
Di Marzo V and Maccarrone M |
FAAH and anandamide: is 2-AG really the odd one out? |
2008 |
Trends Pharmacol. Sci. |
pmid:18394720
|
Solinas M et al. |
The endocannabinoid system in brain reward processes. |
2008 |
Br. J. Pharmacol. |
pmid:18414385
|
Richardson D et al. |
Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. |
2008 |
Arthritis Res. Ther. |
pmid:18416822
|
Bisogno T |
Endogenous cannabinoids: structure and metabolism. |
2008 |
J. Neuroendocrinol. |
pmid:18426492
|
Nomura DK et al. |
Activation of the endocannabinoid system by organophosphorus nerve agents. |
2008 |
Nat. Chem. Biol. |
pmid:18438404
|
Di Marzo V |
Endocannabinoids: synthesis and degradation. |
2008 |
Rev. Physiol. Biochem. Pharmacol. |
pmid:18481028
|
Pertwee RG |
Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond. |
2008 |
Addict Biol |
pmid:18482430
|
Sheinin A et al. |
Endocannabinoid- and mGluR5-dependent short-term synaptic depression in an isolated neuron/bouton preparation from the hippocampal CA1 region. |
2008 |
J. Neurophysiol. |
pmid:18497350
|
Zhang J and Chen C |
Endocannabinoid 2-arachidonoylglycerol protects neurons by limiting COX-2 elevation. |
2008 |
J. Biol. Chem. |
pmid:18534982
|
Di Filippo M et al. |
Abnormalities in the cerebrospinal fluid levels of endocannabinoids in multiple sclerosis. |
2008 |
J. Neurol. Neurosurg. Psychiatr. |
pmid:18535023
|
Nabemoto M et al. |
Release of arachidonic acid by 2-arachidonoyl glycerol and HU210 in PC12 cells; roles of Src, phospholipase C and cytosolic phospholipase A(2)alpha. |
2008 |
Eur. J. Pharmacol. |
pmid:18539271
|
Palmer JA et al. |
Fatty acid amide hydrolase inhibition enhances the anti-allodynic actions of endocannabinoids in a model of acute pain adapted for the mouse. |
2008 |
Neuroscience |
pmid:18541380
|
Qin N et al. |
TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. |
2008 |
J. Neurosci. |
pmid:18550765
|
Motaghedi R and McGraw TE |
The CB1 endocannabinoid system modulates adipocyte insulin sensitivity. |
2008 |
Obesity (Silver Spring) |
pmid:18551116
|
Endsley MP et al. |
Expression and function of fatty acid amide hydrolase in prostate cancer. |
2008 |
Int. J. Cancer |
pmid:18566995
|
Rockwell CE et al. |
A COX-2 metabolite of the endogenous cannabinoid, 2-arachidonyl glycerol, mediates suppression of IL-2 secretion in activated Jurkat T cells. |
2008 |
Biochem. Pharmacol. |
pmid:18571623
|
Njie YF et al. |
Aqueous humor outflow effects of 2-arachidonylglycerol. |
2008 |
Exp. Eye Res. |
pmid:18597752
|
Baldassarri S et al. |
The endocannabinoid 2-arachidonoylglycerol activates human platelets through non-CB1/CB2 receptors. |
2008 |
J. Thromb. Haemost. |
pmid:18647220
|
Hoover HS et al. |
Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18657971
|
Llorente R et al. |
Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid system. |
2008 |
Dev Neurobiol |
pmid:18666205
|
Ellgren M et al. |
Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. |
2008 |
Eur Neuropsychopharmacol |
pmid:18674887
|
Fowler CJ and Ghafouri N |
Does the hydrolysis of 2-arachidonoylglycerol regulate its cellular uptake? |
2008 |
Pharmacol. Res. |
pmid:18675915
|
Burston JJ et al. |
N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:18682568
|
Nomura DK et al. |
Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18752948
|
Placzek EA et al. |
Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. |
2008 |
Neuropharmacology |
pmid:18760289
|
Avraham Y et al. |
2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist, in various rat tissues during the evolution of experimental cholestatic liver disease. |
2008 Jul-Aug |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:18771906
|
Placzek EA et al. |
Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. |
2008 |
J. Neurochem. |
pmid:18778304
|
Fowler CJ |
"The tools of the trade"--an overview of the pharmacology of the endocannabinoid system. |
2008 |
Curr. Pharm. Des. |
pmid:18781976
|
Ruby MA et al. |
Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18794527
|
DiPatrizio NV and Simansky KJ |
Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats. |
2008 |
J. Neurosci. |
pmid:18815256
|
Bajo M et al. |
Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. |
2009 |
J. Neurosci. Res. |
pmid:18816788
|
Catani MV et al. |
Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. |
2009 |
J. Mol. Med. |
pmid:18820887
|
Ortar G et al. |
Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism. |
2008 |
J. Med. Chem. |
pmid:18831576
|
Kreutz S et al. |
2-Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal-cannabidiol-sensitive receptors on microglial cells. |
2009 |
Glia |
pmid:18837048
|
Garcia-Ovejero D et al. |
The endocannabinoid system is modulated in response to spinal cord injury in rats. |
2009 |
Neurobiol. Dis. |
pmid:18930143
|
Lu TS et al. |
Cannabinoids inhibit HIV-1 Gp120-mediated insults in brain microvascular endothelial cells. |
2008 |
J. Immunol. |
pmid:18941231
|
Di Marzo V et al. |
Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. |
2009 |
Diabetologia |
pmid:18972095
|
Hill MN et al. |
Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. |
2008 |
J Neural Transm |
pmid:18974922
|
Bisogno T et al. |
Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo. |
2009 |
Biochim. Biophys. Acta |
pmid:19027877
|
Long JZ et al. |
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. |
2009 |
Nat. Chem. Biol. |
pmid:19029917
|
Vignali M et al. |
The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. |
2009 |
Glia |
pmid:19031444
|
Lehtonen M et al. |
Mass-spectrometric identification of anandamide and 2-arachidonoylglycerol in nematodes. |
2008 |
Chem. Biodivers. |
pmid:19035572
|
Marinelli S et al. |
The endocannabinoid 2-arachidonoylglycerol is responsible for the slow self-inhibition in neocortical interneurons. |
2008 |
J. Neurosci. |
pmid:19074027
|
Jiang LS et al. |
Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. |
2009 |
Cardiovasc. Res. |
pmid:19074161
|
Wang J and Ueda N |
Biology of endocannabinoid synthesis system. |
2009 |
Prostaglandins Other Lipid Mediat. |
pmid:19126434
|
Koppel J et al. |
Endocannabinoids in Alzheimer's disease and their impact on normative cognitive performance: a case-control and cohort study. |
2009 |
Lipids Health Dis |
pmid:19144193
|
Schlosburg JE et al. |
Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. |
2009 |
AAPS J |
pmid:19184452
|
Maccarrone M et al. |
Lipid rafts regulate 2-arachidonoylglycerol metabolism and physiological activity in the striatum. |
2009 |
J. Neurochem. |
pmid:19187444
|
Bisogno T et al. |
Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol. |
2009 |
ChemMedChem |
pmid:19266526
|
Bermúdez-Silva FJ et al. |
The role of the pancreatic endocannabinoid system in glucose metabolism. |
2009 |
Best Pract. Res. Clin. Endocrinol. Metab. |
pmid:19285263
|
Sugiura T |
Physiological roles of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. |
2009 Jan-Feb |
Biofactors |
pmid:19319851
|
Urbanski MJ et al. |
Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling. |
2009 |
Synapse |
pmid:19347961
|
Izzo AA et al. |
Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. |
2009 |
Br. J. Pharmacol. |
pmid:19371345
|
Yates ML and Barker EL |
Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. |
2009 |
Mol. Pharmacol. |
pmid:19389920
|
Hill MN et al. |
Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. |
2009 |
Psychoneuroendocrinology |
pmid:19394765
|
Ishii Y et al. |
F2-isoprostanes and 2-arachidonylglycerol as biomarkers of lipid peroxidation in pigs with hepatic ischemia/reperfusion injury. |
2010 |
J. Surg. Res. |
pmid:19439322
|
Nyilas R et al. |
Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. |
2009 |
Eur. J. Neurosci. |
pmid:19453631
|
Straiker A and Mackie K |
Cannabinoid signaling in inhibitory autaptic hippocampal neurons. |
2009 |
Neuroscience |
pmid:19501632
|
Kinsey SG et al. |
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. |
2009 |
J. Pharmacol. Exp. Ther. |
pmid:19502530
|
Greco R et al. |
Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of rat. |
2010 |
Cephalalgia |
pmid:19515121
|
Dowie MJ et al. |
Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. |
2009 |
Neuroscience |
pmid:19524019
|
Maeda N et al. |
Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. |
2009 |
Fundam Clin Pharmacol |
pmid:19527302
|
Grimaldi P et al. |
The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19541620
|
Bowman AL and Makriyannis A |
Refined homology model of monoacylglycerol lipase: toward a selective inhibitor. |
2009 |
J. Comput. Aided Mol. Des. |
pmid:19543978
|
Batetta B et al. |
Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. |
2009 |
J. Nutr. |
pmid:19549757
|
Guasti L et al. |
Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. |
2009 |
Mol Pain |
pmid:19570201
|
Wakley AA and Rasmussen EB |
Effects of cannabinoid drugs on the reinforcing properties of food in gestationally undernourished rats. |
2009 |
Pharmacol. Biochem. Behav. |
pmid:19602424
|