Fagundo AB et al. |
Modulation of the Endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on Executive Functions in Humans. |
2013 |
PLoS ONE |
pmid:23840456
|
Sergi M et al. |
Determination of the two major endocannabinoids in human plasma by μ-SPE followed by HPLC-MS/MS. |
2013 |
Anal Bioanal Chem |
pmid:22847477
|
Rivera P et al. |
Cocaine self-administration differentially modulates the expression of endogenous cannabinoid system-related proteins in the hippocampus of Lewis vs. Fischer 344 rats. |
2013 |
Int. J. Neuropsychopharmacol. |
pmid:23217608
|
Valdeolivas S et al. |
The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG. |
2013 |
Cell Death Dis |
pmid:24136226
|
Jäntti MH et al. |
Autocrine endocannabinoid signaling through CB1 receptors potentiates OX1 orexin receptor signaling. |
2013 |
Mol. Pharmacol. |
pmid:23233488
|
Su LD et al. |
Retrograde cPLA2α/arachidonic acid/2-AG signaling is essential for cerebellar depolarization-induced suppression of excitation and long-term potentiation. |
2013 |
Cerebellum |
pmid:23307660
|
Keimpema E et al. |
Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons. |
2013 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:23319656
|
Shimizu T et al. |
Stimulatory and inhibitory roles of brain 2-arachidonoylglycerol in bombesin-induced central activation of adrenomedullary outflow in rats. |
2013 |
J. Pharmacol. Sci. |
pmid:23386378
|
Tchantchou F and Zhang Y |
Selective inhibition of alpha/beta-hydrolase domain 6 attenuates neurodegeneration, alleviates blood brain barrier breakdown, and improves functional recovery in a mouse model of traumatic brain injury. |
2013 |
J. Neurotrauma |
pmid:23151067
|
Alhouayek M et al. |
Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6. |
2013 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24101490
|
Iannotti FA et al. |
Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats. |
2013 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:23830028
|
Neumeister A et al. |
Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study. |
2013 |
Mol. Psychiatry |
pmid:23670490
|
Jain T et al. |
Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. |
2013 |
Mol. Pharmacol. |
pmid:23748223
|
Citraro R et al. |
Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. |
2013 |
Neuropharmacology |
pmid:23206503
|
Signorello MG et al. |
The 2-arachidonoylglycerol effect on myosin light chain phosphorylation in human platelets. |
2013 |
Biochimie |
pmid:23702422
|
Lindgren CA et al. |
Cyclooxygenase-2, prostaglandin E2 glycerol ester and nitric oxide are involved in muscarine-induced presynaptic enhancement at the vertebrate neuromuscular junction. |
2013 |
J. Physiol. (Lond.) |
pmid:23818695
|
Frazier CJ |
Preformed vs. on-demand: molecular economics of endocannabinoid signalling. |
2013 |
J. Physiol. (Lond.) |
pmid:24085490
|
Starowicz K et al. |
Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. |
2013 |
PLoS ONE |
pmid:23573230
|
Subbanna S et al. |
Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. |
2013 |
J. Neurosci. |
pmid:23575834
|
Descalzi F et al. |
Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism. |
2013 |
Tissue Eng Part A |
pmid:23578218
|
Morgan CJ et al. |
Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. |
2013 |
Br J Psychiatry |
pmid:23580381
|
Bisogno T et al. |
A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects. |
2013 |
Br. J. Pharmacol. |
pmid:23072382
|
Berge K et al. |
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. |
2013 |
Lipids Health Dis |
pmid:23706001
|
Zygmunt PM et al. |
Monoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1. |
2013 |
PLoS ONE |
pmid:24312564
|
Wang R et al. |
Identification of palmitoyl protein thioesterase 1 in human THP1 monocytes and macrophages and characterization of unique biochemical activities for this enzyme. |
2013 |
Biochemistry |
pmid:24083319
|
Ikeda H et al. |
Activation of spinal cannabinoid CB2 receptors inhibits neuropathic pain in streptozotocin-induced diabetic mice. |
2013 |
Neuroscience |
pmid:23892011
|
Yuan S and Burrell BD |
Nonnociceptive afferent activity depresses nocifensive behavior and nociceptive synapses via an endocannabinoid-dependent mechanism. |
2013 |
J. Neurophysiol. |
pmid:24027102
|
Hill MN et al. |
Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. |
2013 |
Psychoneuroendocrinology |
pmid:24035186
|
Bernabò N et al. |
Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol. |
2013 |
OMICS |
pmid:24117401
|
Gesell FK et al. |
Alterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder. |
2013 |
BMC Vet. Res. |
pmid:24370333
|
Shinjyo N et al. |
Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system. |
2013 |
J. Neurosci. Res. |
pmid:23633391
|
Malenczyk K et al. |
CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. |
2013 |
J. Biol. Chem. |
pmid:24089517
|
Brocato B et al. |
Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. |
2013 |
Placenta |
pmid:24008071
|
Baur R et al. |
Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β₂ subunit of GABA(A) receptors. |
2013 |
J. Neurochem. |
pmid:23600744
|
Fonseca BM et al. |
Endogenous cannabinoids revisited: a biochemistry perspective. |
2013 Apr-May |
Prostaglandins Other Lipid Mediat. |
pmid:23474290
|
Pascual AC et al. |
Aging modifies the enzymatic activities involved in 2-arachidonoylglycerol metabolism. |
2013 Mar-Apr |
Biofactors |
pmid:23281018
|
den Boon FS et al. |
Endocannabinoids produced upon action potential firing evoke a Cl(-) current via type-2 cannabinoid receptors in the medial prefrontal cortex. |
2014 |
Pflugers Arch. |
pmid:24671573
|
Shonesy BC et al. |
Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation. |
2014 |
Cell Rep |
pmid:25466252
|
Gasperi V et al. |
2-Arachidonoylglycerol enhances platelet formation from human megakaryoblasts. |
2014 |
Cell Cycle |
pmid:25427281
|
Zhang J et al. |
Synaptic and cognitive improvements by inhibition of 2-AG metabolism are through upregulation of microRNA-188-3p in a mouse model of Alzheimer's disease. |
2014 |
J. Neurosci. |
pmid:25378159
|
Fezza F et al. |
Endocannabinoids, related compounds and their metabolic routes. |
2014 |
Molecules |
pmid:25347455
|
Flores-Otero J et al. |
Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1. |
2014 |
Nat Commun |
pmid:25081814
|
Smaga I et al. |
Antidepressants and changes in concentration of endocannabinoids and N-acylethanolamines in rat brain structures. |
2014 |
Neurotox Res |
pmid:24652522
|
Karabowicz P et al. |
[Role of endocannabinoid 2-arachidonoylglycerol in the physiology and pathophysiology of the cardiovascular system]. |
2014 |
Postepy Hig Med Dosw (Online) |
pmid:24934539
|
Hillard CJ |
Stress regulates endocannabinoid-CB1 receptor signaling. |
2014 |
Semin. Immunol. |
pmid:24882055
|
Kohnz RA and Nomura DK |
Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoids. |
2014 |
Chem Soc Rev |
pmid:24676249
|
Pastor A et al. |
Analysis of ECs and related compounds in plasma: artifactual isomerization and ex vivo enzymatic generation of 2-MGs. |
2014 |
J. Lipid Res. |
pmid:24610889
|
Stanley CP and O'Sullivan SE |
Cyclooxygenase metabolism mediates vasorelaxation to 2-arachidonoylglycerol (2-AG) in human mesenteric arteries. |
2014 |
Pharmacol. Res. |
pmid:24548820
|
Pérez-Morales M et al. |
2-Arachidonoylglycerol into the lateral hypothalamus improves reduced sleep in adult rats subjected to maternal separation. |
2014 |
Neuroreport |
pmid:25356522
|
Signorello MG and Leoncini G |
Effect of 2-arachidonoylglycerol on myosin light chain phosphorylation and platelet activation: The role of phosphatidylinositol 3 kinase/AKT pathway. |
2014 |
Biochimie |
pmid:25068972
|
Fernández-Suárez D et al. |
Monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model. |
2014 |
Neurobiol. Aging |
pmid:24973119
|
Petrenko AB et al. |
Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol. |
2014 |
Behav. Brain Res. |
pmid:24906199
|
Tsurumura T and Tsuge H |
Substrate selectivity of bacterial monoacylglycerol lipase based on crystal structure. |
2014 |
J. Struct. Funct. Genomics |
pmid:24894647
|
Pascual AC et al. |
Cannabinoid receptor-dependent metabolism of 2-arachidonoylglycerol during aging. |
2014 |
Exp. Gerontol. |
pmid:24768821
|
Gasperi V et al. |
2-Arachidonoylglycerol modulates human endothelial cell/leukocyte interactions by controlling selectin expression through CB1 and CB2 receptors. |
2014 |
Int. J. Biochem. Cell Biol. |
pmid:24721209
|
Lu Y et al. |
Endocannabinoid 2-arachidonylglycerol protects primary cultured neurons against LPS-induced impairments in rat caudate nucleus. |
2014 |
J. Mol. Neurosci. |
pmid:24510751
|
Alhouayek M et al. |
Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy. |
2014 |
Drug Discov. Today |
pmid:23891880
|
Morena M et al. |
Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25489086
|
Khasabova IA et al. |
JZL184 is anti-hyperalgesic in a murine model of cisplatin-induced peripheral neuropathy. |
2014 |
Pharmacol. Res. |
pmid:25304184
|
McDougle DR et al. |
Endocannabinoids anandamide and 2-arachidonoylglycerol are substrates for human CYP2J2 epoxygenase. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:25277139
|
Özdemir B et al. |
Endocannabinoids and inflammatory response in periodontal ligament cells. |
2014 |
PLoS ONE |
pmid:25226300
|
Lau BK et al. |
Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. |
2014 |
Br. J. Pharmacol. |
pmid:25041240
|
Wiley JL et al. |
Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. |
2014 |
Eur. J. Pharmacol. |
pmid:24858366
|
Navarria A et al. |
The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis. |
2014 |
Pharmacol. Res. |
pmid:24861565
|
Nader J et al. |
Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors. |
2014 |
Neuropharmacology |
pmid:24709540
|
Sun LJ et al. |
Endocannabinoid system activation contributes to glucose metabolism disorders of hepatocytes and promotes hepatitis C virus replication. |
2014 |
Int. J. Infect. Dis. |
pmid:24704332
|
Basavarajappa BS et al. |
Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice. |
2014 |
Hippocampus |
pmid:24648181
|
Oleson EB et al. |
Cannabinoid receptor activation shifts temporally engendered patterns of dopamine release. |
2014 |
Neuropsychopharmacology |
pmid:24345819
|
Larose MC et al. |
Mechanisms of human eosinophil migration induced by the combination of IL-5 and the endocannabinoid 2-arachidonoyl-glycerol. |
2014 |
J. Allergy Clin. Immunol. |
pmid:24530098
|
Abdulnour J et al. |
Circulating endocannabinoids in insulin sensitive vs. insulin resistant obese postmenopausal women. A MONET group study. |
2014 |
Obesity (Silver Spring) |
pmid:23616305
|
Aaltonen N et al. |
Brain regional cannabinoid CB(1) receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice. |
2014 |
Eur J Pharm Sci |
pmid:24012970
|
Brantl SA et al. |
Activation of platelets by the endocannabinoids 2-arachidonoylglycerol and virodhamine is mediated by their conversion to arachidonic acid and thromboxane A2, not by activation of cannabinoid receptors. |
2014 |
Platelets |
pmid:24102401
|
Brantl SA et al. |
Mechanism of platelet activation induced by endocannabinoids in blood and plasma. |
2014 |
Platelets |
pmid:23789792
|
Iannotti FA et al. |
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24927567
|
Tiburu EK and Shen L |
Distance measurements and conformational analysis of sn-2-arachidonoylglycerol-membrane sample by ²H-³¹P REDOR NMR. |
2014 |
J. Membr. Biol. |
pmid:24402242
|
Costa MA et al. |
2-arachidonoylglycerol effects in cytotrophoblasts: metabolic enzymes expression and apoptosis in BeWo cells. |
2014 |
Reproduction |
pmid:24324206
|
Laitinen T et al. |
Mutation of Cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency. |
2014 |
Mol. Pharmacol. |
pmid:24368842
|
Koltyn KF et al. |
Mechanisms of exercise-induced hypoalgesia. |
2014 |
J Pain |
pmid:25261342
|
Melis M et al. |
Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats. |
2014 |
J. Neurosci. |
pmid:25232109
|
Alvheim AR et al. |
Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet. |
2014 |
Lipids |
pmid:24081493
|
Pertwee RG |
Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications. |
2014 |
Proc Nutr Soc |
pmid:24135210
|
Burston JJ and Woodhams SG |
Endocannabinoid system and pain: an introduction. |
2014 |
Proc Nutr Soc |
pmid:24148358
|
Desroches J et al. |
Endocannabinoids decrease neuropathic pain-related behavior in mice through the activation of one or both peripheral CBâ‚ and CBâ‚‚ receptors. |
2014 |
Neuropharmacology |
pmid:24148808
|
Yang K et al. |
Differential regulation of NMDAR and NMDAR-mediated metaplasticity by anandamide and 2-AG in the hippocampus. |
2014 |
Hippocampus |
pmid:25087967
|
Fezza F et al. |
Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting. |
2014 |
Mol. Cell. Neurosci. |
pmid:25064144
|
Pulgar VM et al. |
Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis. |
2014 |
Hypertension |
pmid:24935942
|
Jergas B et al. |
O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus. |
2014 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:24853577
|
Pava MJ et al. |
Endocannabinoid modulation of cortical up-states and NREM sleep. |
2014 |
PLoS ONE |
pmid:24520411
|
Sanson B et al. |
Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. |
2014 |
Acta Crystallogr. D Biol. Crystallogr. |
pmid:24531463
|
Ohno-Shosaku T and Kano M |
Endocannabinoid-mediated retrograde modulation of synaptic transmission. |
2014 |
Curr. Opin. Neurobiol. |
pmid:24747340
|
Fowler CJ |
Has FLAT fallen flat? |
2014 |
Trends Pharmacol. Sci. |
pmid:24398120
|
Chianese R et al. |
Hypothalamus-pituitary axis: an obligatory target for endocannabinoids to inhibit steroidogenesis in frog testis. |
2014 |
Gen. Comp. Endocrinol. |
pmid:24566122
|
Zheng Y et al. |
Dexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system. |
2014 |
Eur. J. Pharmacol. |
pmid:24508383
|
Nicolussi S et al. |
Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice. |
2014 |
Pharmacol. Res. |
pmid:24412246
|
Bystrowska B et al. |
Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. |
2014 |
Prog. Neuropsychopharmacol. Biol. Psychiatry |
pmid:24334211
|
Schaefer C et al. |
Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. |
2014 |
Eur Arch Psychiatry Clin Neurosci |
pmid:24253425
|
Limebeer CL et al. |
Attenuation of anticipatory nausea in a rat model of contextually elicited conditioned gaping by enhancement of the endocannabinoid system. |
2014 |
Psychopharmacology (Berl.) |
pmid:24043345
|
Kim J and Watkins BA |
Cannabinoid receptor antagonists and fatty acids alter endocannabinoid system gene expression and COX activity. |
2014 |
J. Nutr. Biochem. |
pmid:24854955
|
Alpár A et al. |
Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling. |
2014 |
Nat Commun |
pmid:25030704
|
Manna JD et al. |
Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells. |
2014 |
J. Biol. Chem. |
pmid:25301951
|