| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Richardson D et al. | Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry. | 2007 | Anal. Biochem. | pmid:17141174 |
| Coopman K et al. | Temporal variation in CB2R levels following T lymphocyte activation: evidence that cannabinoids modulate CXCL12-induced chemotaxis. | 2007 | Int. Immunopharmacol. | pmid:17276894 |
| Hillard CJ et al. | Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. | 2007 | Br. J. Pharmacol. | pmid:17891162 |
| Tanikawa T et al. | Induction of preferential chemotaxis of unstimulated B-lymphocytes by 2-arachidonoylglycerol in immunized mice. | 2007 | Microbiol. Immunol. | pmid:17951991 |
| Hohmann AG | Inhibitors of monoacylglycerol lipase as novel analgesics. | 2007 | Br. J. Pharmacol. | pmid:17293886 |
| Bátkai S et al. | Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. | 2007 | FASEB J. | pmid:17327359 |
| Wang H et al. | Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17259073 |
| Rossi G et al. | Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. | 2007 | Endocrinology | pmid:17110429 |
| Deshpande LS et al. | Endocannabinoids block status epilepticus in cultured hippocampal neurons. | 2007 | Eur. J. Pharmacol. | pmid:17174949 |
| Côté M et al. | Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. | 2007 | Int J Obes (Lond) | pmid:17224929 |
| DeMorrow S et al. | Opposing actions of endocannabinoids on cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid rafts. | 2007 | J. Biol. Chem. | pmid:17329257 |
| Fan SF and Yazulla S | Retrograde endocannabinoid inhibition of goldfish retinal cones is mediated by 2-arachidonoyl glycerol. | 2007 May-Jun | Vis. Neurosci. | pmid:17592669 |
| Sakamoto Y et al. | Clinical responses and improvement of some laboratory parameters following polymyxin B-immobilized fiber treatment in septic shock. | 2007 Sep-Oct | ASAIO J. | pmid:17885340 |
| Nomura DK et al. | Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18752948 |
| DiPatrizio NV and Simansky KJ | Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats. | 2008 | J. Neurosci. | pmid:18815256 |
| Palmer JA et al. | Fatty acid amide hydrolase inhibition enhances the anti-allodynic actions of endocannabinoids in a model of acute pain adapted for the mouse. | 2008 | Neuroscience | pmid:18541380 |
| Hill MN et al. | Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. | 2008 | J Neural Transm | pmid:18974922 |
| Fowler CJ and Ghafouri N | Does the hydrolysis of 2-arachidonoylglycerol regulate its cellular uptake? | 2008 | Pharmacol. Res. | pmid:18675915 |
| Fowler CJ | "The tools of the trade"--an overview of the pharmacology of the endocannabinoid system. | 2008 | Curr. Pharm. Des. | pmid:18781976 |
| Placzek EA et al. | Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. | 2008 | J. Neurochem. | pmid:18778304 |