Bisogno T |
Endogenous cannabinoids: structure and metabolism. |
2008 |
J. Neuroendocrinol. |
pmid:18426492
|
Witting A et al. |
Endocannabinoids accumulate in spinal cord of SOD1 G93A transgenic mice. |
2004 |
J. Neurochem. |
pmid:15189359
|
Belluomo I et al. |
Opposite control of frontocortical 2-arachidonoylglycerol turnover rate by cannabinoid type-1 receptors located on glutamatergic neurons and on astrocytes. |
2015 |
J. Neurochem. |
pmid:25626460
|
GarcÃa del Caño G et al. |
Nuclear diacylglycerol lipase-α in rat brain cortical neurons: evidence of 2-arachidonoylglycerol production in concert with phospholipase C-β activity. |
2015 |
J. Neurochem. |
pmid:25308538
|
Oka S et al. |
Ether-linked analogue of 2-arachidonoylglycerol (noladin ether) was not detected in the brains of various mammalian species. |
2003 |
J. Neurochem. |
pmid:12787057
|
Subbanna S et al. |
Postnatal ethanol exposure alters levels of 2-arachidonylglycerol-metabolizing enzymes and pharmacological inhibition of monoacylglycerol lipase does not cause neurodegeneration in neonatal mice. |
2015 |
J. Neurochem. |
pmid:25857698
|
Wu X et al. |
Alteration of endocannabinoid system in human gliomas. |
2012 |
J. Neurochem. |
pmid:22176552
|
Rhee MH et al. |
Functional role of tryptophan residues in the fourth transmembrane domain of the CB(2) cannabinoid receptor. |
2000 |
J. Neurochem. |
pmid:11080201
|
Palomäki VA et al. |
Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography. |
2007 |
J. Neurochem. |
pmid:17254014
|
Sang N et al. |
COX-2 oxidative metabolite of endocannabinoid 2-AG enhances excitatory glutamatergic synaptic transmission and induces neurotoxicity. |
2007 |
J. Neurochem. |
pmid:17539917
|
Maccarrone M et al. |
Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism. |
2003 |
J. Neurochem. |
pmid:12716433
|
Degn M et al. |
Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice. |
2007 |
J. Neurochem. |
pmid:17868306
|
Sarmad S et al. |
Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. |
2011 |
J. Neurochem. |
pmid:21375532
|
Jarrahian A et al. |
Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. |
2000 |
J. Neurochem. |
pmid:10820223
|
Hansen HH et al. |
Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration. |
2001 |
J. Neurochem. |
pmid:11579150
|
Maccarrone M et al. |
Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages. |
2001 |
J. Neurochem. |
pmid:11461969
|
Alvarez-Jaimes L et al. |
Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. |
2009 |
J. Neurochem. |
pmid:19650871
|
Maccarrone M et al. |
Lipid rafts regulate 2-arachidonoylglycerol metabolism and physiological activity in the striatum. |
2009 |
J. Neurochem. |
pmid:19187444
|
Di Marzo V et al. |
Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. |
2000 |
J. Neurochem. |
pmid:11080195
|
Bisogno T et al. |
Phosphatidic acid as the biosynthetic precursor of the endocannabinoid 2-arachidonoylglycerol in intact mouse neuroblastoma cells stimulated with ionomycin. |
1999 |
J. Neurochem. |
pmid:10217292
|
Placzek EA et al. |
Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. |
2008 |
J. Neurochem. |
pmid:18778304
|
Maccarrone M et al. |
Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. |
2001 |
J. Neurochem. |
pmid:11208922
|
Baur R et al. |
Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β₂ subunit of GABA(A) receptors. |
2013 |
J. Neurochem. |
pmid:23600744
|
Parrish JC and Nichols DE |
Serotonin 5-HT(2A) receptor activation induces 2-arachidonoylglycerol release through a phospholipase c-dependent mechanism. |
2006 |
J. Neurochem. |
pmid:17010161
|
Imperatore R et al. |
Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CBâ‚R signaling and anxiety-like behavior. |
2015 |
J. Neurochem. |
pmid:26223500
|
Zou Z et al. |
Endocannabinoid 2-Arachidonoylglycerol Suppresses LPS-Induced Inhibition of A-Type Potassium Channel Currents in Caudate Nucleus Neurons Through CB1 Receptor. |
2016 |
J. Mol. Neurosci. |
pmid:27129498
|
Zou Z et al. |
Effect of Homocysteine on Voltage-Gated Sodium Channel Currents in Primary Cultured Rat Caudate Nucleus Neurons and Its Modulation by 2-Arachidonylglycerol. |
2015 |
J. Mol. Neurosci. |
pmid:26179279
|
Dong M et al. |
Endocannabinoid 2-arachidonylglycerol protects primary cultured neurons against homocysteine-induced impairments in rat caudate nucleus through CB1 receptor. |
2015 |
J. Mol. Neurosci. |
pmid:25007951
|
Lu Y et al. |
Endocannabinoid 2-arachidonylglycerol protects primary cultured neurons against LPS-induced impairments in rat caudate nucleus. |
2014 |
J. Mol. Neurosci. |
pmid:24510751
|
D'Argenio G et al. |
Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. |
2007 |
J. Mol. Med. |
pmid:17396241
|
Catani MV et al. |
Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. |
2009 |
J. Mol. Med. |
pmid:18820887
|
Amorós I et al. |
Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner. |
2010 |
J. Mol. Cell. Cardiol. |
pmid:19616555
|
Weis F et al. |
Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. |
2010 |
J. Mol. Cell. Cardiol. |
pmid:19931541
|
Tiburu EK and Shen L |
Distance measurements and conformational analysis of sn-2-arachidonoylglycerol-membrane sample by ²H-³¹P REDOR NMR. |
2014 |
J. Membr. Biol. |
pmid:24402242
|
Lambert DM and Fowler CJ |
The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications. |
2005 |
J. Med. Chem. |
pmid:16078824
|
Cisneros JA et al. |
Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. |
2007 |
J. Med. Chem. |
pmid:17764163
|
Barnett-Norris J et al. |
Exploration of biologically relevant conformations of anandamide, 2-arachidonylglycerol, and their analogues using conformational memories. |
1998 |
J. Med. Chem. |
pmid:9822555
|
MartÃn-Couce L et al. |
Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors. |
2011 |
J. Med. Chem. |
pmid:21675776
|
van der Stelt M et al. |
Oxygenated metabolites of anandamide and 2-arachidonoylglycerol: conformational analysis and interaction with cannabinoid receptors, membrane transporter, and fatty acid amide hydrolase. |
2002 |
J. Med. Chem. |
pmid:12166944
|
Ortar G et al. |
Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism. |
2008 |
J. Med. Chem. |
pmid:18831576
|
Brizzi A et al. |
Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. |
2011 |
J. Med. Chem. |
pmid:22044209
|
Brindisi M et al. |
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. |
2016 |
J. Med. Chem. |
pmid:26888301
|
Nithipatikom K et al. |
A novel activity of microsomal epoxide hydrolase: metabolism of the endocannabinoid 2-arachidonoylglycerol. |
2014 |
J. Lipid Res. |
pmid:24958911
|
Pastor A et al. |
Analysis of ECs and related compounds in plasma: artifactual isomerization and ex vivo enzymatic generation of 2-MGs. |
2014 |
J. Lipid Res. |
pmid:24610889
|
Fanelli F et al. |
Estimation of reference intervals of five endocannabinoids and endocannabinoid related compounds in human plasma by two dimensional-LC/MS/MS. |
2012 |
J. Lipid Res. |
pmid:22172516
|
Dong L et al. |
Interactions of 2-O-arachidonylglycerol ether and ibuprofen with the allosteric and catalytic subunits of human COX-2. |
2016 |
J. Lipid Res. |
pmid:27059979
|
Kantae V et al. |
Quantitative profiling of endocannabinoids and related -acylethanolamines in human CSF using nano LC-MS/MS. |
2017 |
J. Lipid Res. |
pmid:27999147
|
Wollank Y et al. |
Inhibition of FAAH confers increased stem cell migration via PPARα. |
2015 |
J. Lipid Res. |
pmid:26263913
|
Navia-Paldanius D et al. |
Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12). |
2012 |
J. Lipid Res. |
pmid:22969151
|
Skonberg C et al. |
Pitfalls in the sample preparation and analysis of N-acylethanolamines. |
2010 |
J. Lipid Res. |
pmid:20447930
|
Turcotte C et al. |
Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites. |
2015 |
J. Leukoc. Biol. |
pmid:25877930
|
Oka S et al. |
2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils. |
2004 |
J. Leukoc. Biol. |
pmid:15316028
|
Chouinard F et al. |
2-Arachidonoyl-glycerol- and arachidonic acid-stimulated neutrophils release antimicrobial effectors against E. coli, S. aureus, HSV-1, and RSV. |
2013 |
J. Leukoc. Biol. |
pmid:23242611
|
Kaplan BL et al. |
2-Arachidonoyl-glycerol suppresses interferon-gamma production in phorbol ester/ionomycin-activated mouse splenocytes independent of CB1 or CB2. |
2005 |
J. Leukoc. Biol. |
pmid:15774549
|
Sipe JC et al. |
Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: possible risk for autoimmune disorders. |
2005 |
J. Leukoc. Biol. |
pmid:15845647
|
Czifra G et al. |
Endocannabinoids regulate growth and survival of human eccrine sweat gland-derived epithelial cells. |
2012 |
J. Invest. Dermatol. |
pmid:22513781
|
Marazzi J et al. |
Endocannabinoid content in fetal bovine sera - unexpected effects on mononuclear cells and osteoclastogenesis. |
2011 |
J. Immunol. Methods |
pmid:21920367
|
Sancho R et al. |
Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine. |
2005 |
J. Immunol. |
pmid:16148147
|
Bari M et al. |
Effect of lipid rafts on Cb2 receptor signaling and 2-arachidonoyl-glycerol metabolism in human immune cells. |
2006 |
J. Immunol. |
pmid:17015679
|
Lu TS et al. |
Cannabinoids inhibit HIV-1 Gp120-mediated insults in brain microvascular endothelial cells. |
2008 |
J. Immunol. |
pmid:18941231
|
Oka S et al. |
Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. |
2006 |
J. Immunol. |
pmid:17142782
|
Chouinard F et al. |
The endocannabinoid 2-arachidonoyl-glycerol activates human neutrophils: critical role of its hydrolysis and de novo leukotriene B4 biosynthesis. |
2011 |
J. Immunol. |
pmid:21278347
|
Gaskari SA et al. |
Blunted cardiac response to hemorrhage in cirrhotic rats is mediated by local macrophage-released endocannabinoids. |
2015 |
J. Hepatol. |
pmid:25640062
|
Muppidi JR et al. |
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. |
2011 |
J. Exp. Med. |
pmid:21875957
|
Bowman AL and Makriyannis A |
Refined homology model of monoacylglycerol lipase: toward a selective inhibitor. |
2009 |
J. Comput. Aided Mol. Des. |
pmid:19543978
|
Li Q and Burrell BD |
Two forms of long-term depression in a polysynaptic pathway in the leech CNS: one NMDA receptor-dependent and the other cannabinoid-dependent. |
2009 |
J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. |
pmid:19657662
|
Suárez J et al. |
Endocannabinoid system in the adult rat circumventricular areas: an immunohistochemical study. |
2010 |
J. Comp. Neurol. |
pmid:20533360
|
Hanlon EC et al. |
Circadian rhythm of circulating levels of the endocannabinoid 2-arachidonoylglycerol. |
2015 |
J. Clin. Endocrinol. Metab. |
pmid:25368979
|
Heinitz S et al. |
Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage. |
2018 |
J. Clin. Endocrinol. Metab. |
pmid:29300902
|
Monteleone P et al. |
Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study. |
2012 |
J. Clin. Endocrinol. Metab. |
pmid:22442280
|
Jumpertz R et al. |
Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. |
2011 |
J. Clin. Endocrinol. Metab. |
pmid:21177788
|
Obata T et al. |
Simultaneous determination of endocannabinoids (arachidonylethanolamide and 2-arachidonylglycerol) and isoprostane (8-epiprostaglandin F2alpha) by gas chromatography-mass spectrometry-selected ion monitoring for medical samples. |
2003 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:12829006
|
Zoerner AA et al. |
Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. |
2012 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:21752730
|
Mwanza C et al. |
Simultaneous HPLC-APCI-MS/MS quantification of endogenous cannabinoids and glucocorticoids in hair. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:27318292
|
Zhang J et al. |
Inhibition of monoacylglycerol lipase prevents chronic traumatic encephalopathy-like neuropathology in a mouse model of repetitive mild closed head injury. |
2015 |
J. Cereb. Blood Flow Metab. |
pmid:25492114
|
Panikashvili D et al. |
CB1 cannabinoid receptors are involved in neuroprotection via NF-kappa B inhibition. |
2005 |
J. Cereb. Blood Flow Metab. |
pmid:15729296
|
Pisanti S et al. |
Anandamide drives cell cycle progression through CB1 receptors in a rat model of synchronized liver regeneration. |
2015 |
J. Cell. Physiol. |
pmid:25684344
|
Signorello MG and Leoncini G |
Regulation of cAMP Intracellular Levels in Human Platelets Stimulated by 2-Arachidonoylglycerol. |
2016 |
J. Cell. Biochem. |
pmid:26460717
|
Signorello MG and Leoncini G |
Activation of CaMKKβ/AMPKα pathway by 2-AG in human platelets. |
2018 |
J. Cell. Biochem. |
pmid:28661046
|
Signorello MG et al. |
Activation by 2-arachidonoylglycerol of platelet p38MAPK/cPLA2 pathway. |
2011 |
J. Cell. Biochem. |
pmid:21608016
|
Bisogno T et al. |
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. |
2003 |
J. Cell Biol. |
pmid:14610053
|
Schaich CL et al. |
Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity. |
2015 |
J. Cardiovasc. Pharmacol. |
pmid:25636077
|
Wang PF et al. |
Cannabinoid-2 receptor activation protects against infarct and ischemia-reperfusion heart injury. |
2012 |
J. Cardiovasc. Pharmacol. |
pmid:22113346
|
Wagner JA et al. |
2-Arachidonylglycerol acting on CB1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts. |
2006 |
J. Cardiovasc. Pharmacol. |
pmid:16775503
|
Wagner JA et al. |
Coronary vasodilator effects of endogenous cannabinoids in vasopressin-preconstricted unpaced rat isolated hearts. |
2005 |
J. Cardiovasc. Pharmacol. |
pmid:16116341
|
Musee J and Marnett LJ |
Prostaglandin H synthase-2-catalyzed oxygenation of 2-arachidonoylglycerol is more sensitive to peroxide tone than oxygenation of arachidonic acid. |
2012 |
J. Biol. Chem. |
pmid:22942274
|
Kishimoto S et al. |
2-arachidonoylglycerol induces the migration of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism. |
2003 |
J. Biol. Chem. |
pmid:12711605
|
Pucci M et al. |
Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor. |
2012 |
J. Biol. Chem. |
pmid:22431736
|
Tanveer R et al. |
The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats. |
2012 |
J. Biol. Chem. |
pmid:22891244
|
Chicca A et al. |
Evidence for bidirectional endocannabinoid transport across cell membranes. |
2012 |
J. Biol. Chem. |
pmid:22879589
|
Jiang S et al. |
Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. |
2010 |
J. Biol. Chem. |
pmid:20826813
|
Vecchio AJ and Malkowski MG |
The structural basis of endocannabinoid oxygenation by cyclooxygenase-2. |
2011 |
J. Biol. Chem. |
pmid:21489986
|
DeMorrow S et al. |
Opposing actions of endocannabinoids on cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid rafts. |
2007 |
J. Biol. Chem. |
pmid:17329257
|
Kurihara R et al. |
Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils. |
2006 |
J. Biol. Chem. |
pmid:16513651
|
Kozak KR et al. |
Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid 2-arachidonylglycerol. |
2001 |
J. Biol. Chem. |
pmid:11402053
|
Yu Y et al. |
Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality. |
2007 |
J. Biol. Chem. |
pmid:17110378
|
Hurst DP et al. |
A lipid pathway for ligand binding is necessary for a cannabinoid G protein-coupled receptor. |
2010 |
J. Biol. Chem. |
pmid:20220143
|
Chanda D et al. |
2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes. |
2017 |
J. Biol. Chem. |
pmid:28320859
|
Manna JD et al. |
Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells. |
2014 |
J. Biol. Chem. |
pmid:25301951
|
Kozak KR et al. |
15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist. |
2002 |
J. Biol. Chem. |
pmid:11956198
|