| MeSH term | MeSH ID | Detail |
|---|---|---|
| Fetal Nutrition Disorders | D048070 | 1 associated lipids |
| Ganglion Cysts | D045888 | 1 associated lipids |
| Neuromyelitis Optica | D009471 | 2 associated lipids |
| Acute Pain | D059787 | 3 associated lipids |
| Fragile X Syndrome | D005600 | 5 associated lipids |
| Head Injuries, Closed | D016489 | 5 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Cholangiocarcinoma | D018281 | 7 associated lipids |
| Hepatic Encephalopathy | D006501 | 9 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Hyperkinesis | D006948 | 11 associated lipids |
| Encephalitis | D004660 | 15 associated lipids |
| Liver Cirrhosis, Alcoholic | D008104 | 17 associated lipids |
| Hypothermia | D007035 | 19 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
| Hypoxia-Ischemia, Brain | D020925 | 22 associated lipids |
2-arachidonoylglycerol
2-arachidonoylglycerol is a lipid of Glycerolipids (GL) class. 2-arachidonoylglycerol is associated with abnormalities such as Atherosclerosis, Heart Diseases, Inflammatory disorder, Colitis and Peripheral Neuropathy. The involved functions are known as Immunoreactivity, inhibitors, Stimulus, Esthesia and Signal Transduction. 2-arachidonoylglycerol often locates in Back, Presynaptic Terminals, Brain region, Blood and Body tissue. The associated genes with 2-arachidonoylglycerol are ADRBK1 gene, Homologous Gene, MGLL gene, PLA2G4A gene and peptide V. The related lipids are oleoylethanolamide, Lipopolysaccharides, Promega, stearic acid and 1-stearoyl-2-arachidonoylglycerol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-arachidonoylglycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-arachidonoylglycerol?
2-arachidonoylglycerol is suspected in Atherosclerosis, Heart Diseases, Sweet's Syndrome, Colitis, Dehydration, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-arachidonoylglycerol
PubChem Associated disorders and diseases
What pathways are associated with 2-arachidonoylglycerol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-arachidonoylglycerol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 2-arachidonoylglycerol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2-arachidonoylglycerol?
Knock-out
Knock-out are used in the study 'Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.' (Walentiny DM et al., 2015), Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012) and Knock-out are used in the study 'Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.' (Viader A et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with 2-arachidonoylglycerol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lau BK et al. | Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. | 2014 | Br. J. Pharmacol. | pmid:25041240 |
| Laprairie RB et al. | Type 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons. | 2014 | J. Biol. Chem. | pmid:25037227 |
| Murataeva N et al. | Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS. | 2014 | Br. J. Pharmacol. | pmid:24102242 |
| Rea K et al. | Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state. | 2014 | Eur. J. Neurosci. | pmid:24494683 |
| Pascual AC et al. | Aging modifies the enzymatic activities involved in 2-arachidonoylglycerol metabolism. | 2013 Mar-Apr | Biofactors | pmid:23281018 |
| Fonseca BM et al. | Endogenous cannabinoids revisited: a biochemistry perspective. | 2013 Apr-May | Prostaglandins Other Lipid Mediat. | pmid:23474290 |
| Sergi M et al. | Determination of the two major endocannabinoids in human plasma by μ-SPE followed by HPLC-MS/MS. | 2013 | Anal Bioanal Chem | pmid:22847477 |
| Ueda N et al. | Metabolism of endocannabinoids and related N-acylethanolamines: canonical and alternative pathways. | 2013 | FEBS J. | pmid:23425575 |
| Sugaya Y et al. | The endocannabinoid 2-arachidonoylglycerol negatively regulates habituation by suppressing excitatory recurrent network activity and reducing long-term potentiation in the dentate gyrus. | 2013 | J. Neurosci. | pmid:23426686 |
| Jain T et al. | Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. | 2013 | Mol. Pharmacol. | pmid:23748223 |
| Signorello MG et al. | The 2-arachidonoylglycerol effect on myosin light chain phosphorylation in human platelets. | 2013 | Biochimie | pmid:23702422 |
| Higgins A et al. | Differential modulation of nociceptive versus non-nociceptive synapses by endocannabinoids. | 2013 | Mol Pain | pmid:23725095 |
| Almeida-Santos AF et al. | Modulation of anxiety-like behavior by the endocannabinoid 2-arachidonoylglycerol (2-AG) in the dorsolateral periaqueductal gray. | 2013 | Behav. Brain Res. | pmid:23714073 |
| Perez-Rosello T et al. | Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis. | 2013 | J. Neurosci. | pmid:23719795 |
| Yang Y et al. | Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury. | 2013 | Cell. Signal. | pmid:23142606 |
| Guindon J et al. | Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment. | 2013 | Pharmacol. Res. | pmid:23127915 |
| Starowicz K et al. | Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. | 2013 | PLoS ONE | pmid:23573230 |
| Subbanna S et al. | Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. | 2013 | J. Neurosci. | pmid:23575834 |
| Blankman JL and Cravatt BF | Chemical probes of endocannabinoid metabolism. | 2013 | Pharmacol. Rev. | pmid:23512546 |
| Blasio A et al. | Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdala. | 2013 | Neuropsychopharmacology | pmid:23793355 |