Cobellis G et al. |
A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up. |
2010 |
Biol. Reprod. |
pmid:19812302
|
Yasuo S et al. |
Localization of an endocannabinoid system in the hypophysial pars tuberalis and pars distalis of man. |
2010 |
Cell Tissue Res. |
pmid:20957495
|
Arevalo-Martin A et al. |
The endocannabinoid 2-arachidonoylglycerol reduces lesion expansion and white matter damage after spinal cord injury. |
2010 |
Neurobiol. Dis. |
pmid:20156559
|
Eisenstein SA et al. |
A role for 2-arachidonoylglycerol and endocannabinoid signaling in the locomotor response to novelty induced by olfactory bulbectomy. |
2010 |
Pharmacol. Res. |
pmid:20044005
|
Amorós I et al. |
Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner. |
2010 |
J. Mol. Cell. Cardiol. |
pmid:19616555
|
Frampton G et al. |
Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. |
2010 |
Exp. Cell Res. |
pmid:20347808
|
Caraceni P et al. |
Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. |
2010 |
Liver Int. |
pmid:19840245
|
Piccinetti CC et al. |
Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. |
2010 |
Gen. Comp. Endocrinol. |
pmid:19800340
|
Fonseca BM et al. |
The endocannabinoid 2-arachidonoylglycerol (2-AG) and metabolizing enzymes during rat fetoplacental development: a role in uterine remodelling. |
2010 |
Int. J. Biochem. Cell Biol. |
pmid:20727980
|
Romigi A et al. |
Cerebrospinal fluid levels of the endocannabinoid anandamide are reduced in patients with untreated newly diagnosed temporal lobe epilepsy. |
2010 |
Epilepsia |
pmid:19817812
|
Lerner TN et al. |
Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. |
2010 |
J. Neurosci. |
pmid:20147543
|
Reggio PH |
Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown. |
2010 |
Curr. Med. Chem. |
pmid:20166921
|
Evagorou A et al. |
Hydrolysis of 2-arachidonoylglycerol in Tetrahymena thermophila. Identification and partial characterization of a Monoacylglycerol Lipase-like enzyme. |
2010 |
Eur. J. Protistol. |
pmid:20889319
|
Sang N et al. |
Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. |
2010 |
Neurochem. Int. |
pmid:20064571
|
Maccarrone M et al. |
Abnormal mGlu 5 receptor/endocannabinoid coupling in mice lacking FMRP and BC1 RNA. |
2010 |
Neuropsychopharmacology |
pmid:20393458
|
Hurst DP et al. |
A lipid pathway for ligand binding is necessary for a cannabinoid G protein-coupled receptor. |
2010 |
J. Biol. Chem. |
pmid:20220143
|
Telleria-Diaz A et al. |
Spinal antinociceptive effects of cyclooxygenase inhibition during inflammation: Involvement of prostaglandins and endocannabinoids. |
2010 |
Pain |
pmid:19879047
|
Bradshaw H |
CB1-induced side effects of specific COX-2 inhibitors: a feature, not a bug. |
2010 |
Pain |
pmid:19913999
|
Zhang MY et al. |
Simultaneous determination of 2-arachidonoylglycerol, 1-arachidonoylglycerol and arachidonic acid in mouse brain tissue using liquid chromatography/tandem mass spectrometry. |
2010 |
J Mass Spectrom |
pmid:19950120
|
Labar G et al. |
Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling. |
2010 |
Chembiochem |
pmid:19957260
|
Frazier CJ |
Key questions of endocannabinoid signalling in the CNS: which, where and when? |
2011 |
J. Physiol. (Lond.) |
pmid:22001725
|
Nomura DK et al. |
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation. |
2011 |
Science |
pmid:22021672
|
Muppidi JR et al. |
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. |
2011 |
J. Exp. Med. |
pmid:21875957
|
Zhang L et al. |
Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase. |
2011 |
PLoS ONE |
pmid:21305054
|
Schalk-Hihi C et al. |
Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Ã… resolution. |
2011 |
Protein Sci. |
pmid:21308848
|
Duggan KC et al. |
(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. |
2011 |
Nat. Chem. Biol. |
pmid:22053353
|
Puente N et al. |
Polymodal activation of the endocannabinoid system in the extended amygdala. |
2011 |
Nat. Neurosci. |
pmid:22057189
|
Stella N |
Cell biology. Anatomy of prostaglandin signals. |
2011 |
Science |
pmid:22076368
|
Patsenker E et al. |
Cannabinoid receptor type I modulates alcohol-induced liver fibrosis. |
2011 |
Mol. Med. |
pmid:21863215
|
Hill MN et al. |
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. |
2011 |
J. Neurosci. |
pmid:21775596
|
Sumislawski JJ et al. |
Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation. |
2011 |
Neuropsychopharmacology |
pmid:21849983
|
Zhong P et al. |
Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. |
2011 |
J. Physiol. (Lond.) |
pmid:21911610
|
Marazzi J et al. |
Endocannabinoid content in fetal bovine sera - unexpected effects on mononuclear cells and osteoclastogenesis. |
2011 |
J. Immunol. Methods |
pmid:21920367
|
Signorello MG et al. |
Activation by 2-arachidonoylglycerol of platelet p38MAPK/cPLA2 pathway. |
2011 |
J. Cell. Biochem. |
pmid:21608016
|
Du H et al. |
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ. |
2011 |
Br. J. Pharmacol. |
pmid:21501147
|
Raman P et al. |
15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma. |
2011 |
Mol. Pharmacol. |
pmid:21511917
|
Bari M et al. |
Characterization of the endocannabinoid system in mouse embryonic stem cells. |
2011 |
Stem Cells Dev. |
pmid:20446814
|
Higuchi S et al. |
Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors. |
2011 |
Behav. Brain Res. |
pmid:20817042
|
Ludányi A et al. |
Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. |
2011 |
Neuroscience |
pmid:21035522
|
Hofmann ME et al. |
Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. |
2011 |
J. Physiol. (Lond.) |
pmid:21646412
|
MartÃn-Couce L et al. |
Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors. |
2011 |
J. Med. Chem. |
pmid:21675776
|
Chanda D et al. |
Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes. |
2011 |
J. Biol. Chem. |
pmid:21693703
|
Busquets-Garcia A et al. |
Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. |
2011 |
Biol. Psychiatry |
pmid:21684528
|
Signorello MG et al. |
Activation of human platelets by 2-arachidonoylglycerol: role of PKC in NO/cGMP pathway modulation. |
2011 |
Curr Neurovasc Res |
pmid:21675954
|
Sarmad S et al. |
Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. |
2011 |
J. Neurochem. |
pmid:21375532
|
Marrs WR et al. |
Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons. |
2011 |
J. Biol. Chem. |
pmid:21665953
|
Gantayet A et al. |
Endocannabinoids and diacylglycerol kinase activity. |
2011 |
Biochim. Biophys. Acta |
pmid:21194521
|
Duclos RI et al. |
A methodology for radiolabeling of the endocannabinoid 2-arachidonoylglycerol (2-AG). |
2011 |
J. Org. Chem. |
pmid:21370840
|
Shimizu T et al. |
Endogenously generated 2-arachidonoylglycerol plays an inhibitory role in bombesin-induced activation of central adrenomedullary outflow in rats. |
2011 |
Eur. J. Pharmacol. |
pmid:21371452
|
Lourbopoulos A et al. |
Administration of 2-arachidonoylglycerol ameliorates both acute and chronic experimental autoimmune encephalomyelitis. |
2011 |
Brain Res. |
pmid:21406188
|
Kortleven C et al. |
The endocannabinoid 2-arachidonoylglycerol inhibits long-term potentiation of glutamatergic synapses onto ventral tegmental area dopamine neurons in mice. |
2011 |
Eur. J. Neurosci. |
pmid:21410793
|
Oudin MJ et al. |
Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain. |
2011 |
J. Neurosci. |
pmid:21411643
|
Hashimotodani Y et al. |
Neuronal protease-activated receptor 1 drives synaptic retrograde signaling mediated by the endocannabinoid 2-arachidonoylglycerol. |
2011 |
J. Neurosci. |
pmid:21414931
|
Howlett AC et al. |
Endocannabinoid tone versus constitutive activity of cannabinoid receptors. |
2011 |
Br. J. Pharmacol. |
pmid:21545414
|
Taschler U et al. |
Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. |
2011 |
J. Biol. Chem. |
pmid:21454566
|
Mulder J et al. |
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. |
2011 |
Brain |
pmid:21459826
|
Carr RL et al. |
Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. |
2011 |
Toxicol. Sci. |
pmid:21507991
|
Chiba T et al. |
A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. |
2011 |
J. Pharm. Pharmacol. |
pmid:21492165
|
Vecchio AJ and Malkowski MG |
The structural basis of endocannabinoid oxygenation by cyclooxygenase-2. |
2011 |
J. Biol. Chem. |
pmid:21489986
|
Balenga NA et al. |
GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. |
2011 |
Cell Res. |
pmid:21467997
|
Chen X et al. |
Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults. |
2011 |
Neuroscience |
pmid:21256197
|
Yoshida T et al. |
Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21282604
|
Liao HT et al. |
Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition. |
2011 |
Br. J. Pharmacol. |
pmid:21232043
|
Soderstrom K et al. |
Cannabinoid exposure during zebra finch sensorimotor vocal learning persistently alters expression of endocannabinoid signaling elements and acute agonist responsiveness. |
2011 |
BMC Neurosci |
pmid:21211022
|
De Petrocellis L et al. |
Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. |
2011 |
Br. J. Pharmacol. |
pmid:21175579
|
Petrosino S et al. |
Alteration of the endocannabinoid system in mouse brain during prion disease. |
2011 |
Neuroscience |
pmid:21195746
|
Jumpertz R et al. |
Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. |
2011 |
J. Clin. Endocrinol. Metab. |
pmid:21177788
|
Sciolino NR et al. |
Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats. |
2011 |
Pharmacol. Res. |
pmid:21600985
|
Uchigashima M et al. |
Molecular and morphological configuration for 2-arachidonoylglycerol-mediated retrograde signaling at mossy cell-granule cell synapses in the dentate gyrus. |
2011 |
J. Neurosci. |
pmid:21613483
|
Di Marzo V |
Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. |
2011 |
Nat. Neurosci. |
pmid:21187849
|
Alhouayek M et al. |
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. |
2011 |
FASEB J. |
pmid:21551239
|
Justinová Z et al. |
The endogenous cannabinoid 2-arachidonoylglycerol is intravenously self-administered by squirrel monkeys. |
2011 |
J. Neurosci. |
pmid:21562266
|
Guindon J et al. |
Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. |
2011 |
Br. J. Pharmacol. |
pmid:21198549
|
Borges BC et al. |
Leptin resistance and desensitization of hypophagia during prolonged inflammatory challenge. |
2011 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:21343543
|
Shekhar C |
Mixed signals: cannabinoid system offers new therapeutic possibilities as well as challenges. |
2011 |
Chem. Biol. |
pmid:21609833
|
Ho YC et al. |
Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. |
2011 |
J. Neurosci. |
pmid:21994376
|
Quercioli A et al. |
Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. |
2011 |
Eur. Heart J. |
pmid:21303779
|
Cippitelli A et al. |
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. |
2011 |
PLoS ONE |
pmid:22140525
|
Brizzi A et al. |
Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. |
2011 |
J. Med. Chem. |
pmid:22044209
|
Yoshino H et al. |
Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. |
2011 |
J. Physiol. (Lond.) |
pmid:21807615
|
Chouinard F et al. |
The endocannabinoid 2-arachidonoyl-glycerol activates human neutrophils: critical role of its hydrolysis and de novo leukotriene B4 biosynthesis. |
2011 |
J. Immunol. |
pmid:21278347
|
Khasabova IA et al. |
Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. |
2011 |
Pharmacol. Res. |
pmid:21440630
|
Catanzaro G et al. |
Effect of capacitation on the endocannabinoid system of mouse sperm. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21723369
|
Ueda N et al. |
Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol. |
2011 Jan-Feb |
Biofactors |
pmid:21328621
|
Hutchins-Wiese HL et al. |
Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle. |
2012 |
J. Nutr. Biochem. |
pmid:22051448
|
Heyman E et al. |
Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. |
2012 |
Psychoneuroendocrinology |
pmid:22029953
|
Thomas KC et al. |
Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. |
2012 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:21949157
|
Schulte K et al. |
Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor. |
2012 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:22215206
|
Gatta-Cherifi B et al. |
Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity. |
2012 |
Int J Obes (Lond) |
pmid:21844878
|
Kortleven C et al. |
Neurotensin inhibits glutamate-mediated synaptic inputs onto ventral tegmental area dopamine neurons through the release of the endocannabinoid 2-AG. |
2012 |
Neuropharmacology |
pmid:22884466
|
Tanimura A et al. |
Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22783023
|
Monteleone P et al. |
Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study. |
2012 |
J. Clin. Endocrinol. Metab. |
pmid:22442280
|
Whyte LS et al. |
Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro. |
2012 |
Br. J. Pharmacol. |
pmid:21649637
|
Booker L et al. |
The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. |
2012 |
Br. J. Pharmacol. |
pmid:21506952
|
Di Marzo V and De Petrocellis L |
Why do cannabinoid receptors have more than one endogenous ligand? |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108541
|
Puighermanal E et al. |
Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108544
|
Starowicz K and Przewlocka B |
Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108547
|
Rani Sagar D et al. |
Dynamic changes to the endocannabinoid system in models of chronic pain. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108548
|
Navia-Paldanius D et al. |
Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12). |
2012 |
J. Lipid Res. |
pmid:22969151
|
Zoerner AA et al. |
Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. |
2012 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:21752730
|