Sugiura T and Waku K |
Cannabinoid receptors and their endogenous ligands. |
2002 |
J. Biochem. |
pmid:12097154
|
Jordà MA et al. |
Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol. |
2002 |
Blood |
pmid:11929767
|
Vannacci A et al. |
Down-regulation by cannabinoids of the immunological activation of human basophils and guinea pig mast cells. |
2002 |
Inflamm. Res. |
pmid:12013387
|
Kirkham TC et al. |
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. |
2002 |
Br. J. Pharmacol. |
pmid:12055133
|
Kreitzer AC and Regehr WG |
Retrograde signaling by endocannabinoids. |
2002 |
Curr. Opin. Neurobiol. |
pmid:12049940
|
Nakane S et al. |
2-Arachidonoyl-sn-glycero-3-phosphate, an arachidonic acid-containing lysophosphatidic acid: occurrence and rapid enzymatic conversion to 2-arachidonoyl-sn-glycerol, a cannabinoid receptor ligand, in rat brain. |
2002 |
Arch. Biochem. Biophys. |
pmid:12051682
|
Maccarrone M et al. |
Endocannabinoid degradation, endotoxic shock and inflammation. |
2002 |
Curr Drug Targets Inflamm Allergy |
pmid:14561206
|
Laine K et al. |
Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid. |
2002 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12356827
|
Darmani NA |
The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:11752094
|
González S et al. |
Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. |
2002 |
Brain Res. |
pmid:12393235
|
Rouzer CA et al. |
Chemical stability of 2-arachidonylglycerol under biological conditions. |
2002 |
Chem. Phys. Lipids |
pmid:12270674
|
Bisogno T et al. |
Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications. |
2002 |
Curr. Pharm. Des. |
pmid:11945157
|
Lichtman AH et al. |
Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:12065702
|
Dinh TP et al. |
A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation. |
2002 |
Chem. Phys. Lipids |
pmid:12505697
|
Kojima S et al. |
Contractile response to a cannabimimetic eicosanoid, 2-arachidonoylglycerol, of longitudinal smooth muscle from the guinea-pig distal colon in vitro. |
2002 |
Eur. J. Pharmacol. |
pmid:12063081
|
Razdan RK and Mahadevan A |
Recent advances in the synthesis of endocannabinoid related ligands. |
2002 |
Chem. Phys. Lipids |
pmid:12505687
|
Kunos G et al. |
The quest for a vascular endothelial cannabinoid receptor. |
2002 |
Chem. Phys. Lipids |
pmid:12505689
|
Schmid HH et al. |
Cell signaling by endocannabinoids and their congeners: questions of selectivity and other challenges. |
2002 |
Chem. Phys. Lipids |
pmid:12505695
|
Kozak KR et al. |
Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. |
2002 |
J. Biol. Chem. |
pmid:12244105
|
van der Stelt M et al. |
Oxygenated metabolites of anandamide and 2-arachidonoylglycerol: conformational analysis and interaction with cannabinoid receptors, membrane transporter, and fatty acid amide hydrolase. |
2002 |
J. Med. Chem. |
pmid:12166944
|
Mechoulam R et al. |
Cannabinoids and brain injury: therapeutic implications. |
2002 |
Trends Mol Med |
pmid:11815270
|
Dinh TP et al. |
Brain monoglyceride lipase participating in endocannabinoid inactivation. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12136125
|
Matias I et al. |
Presence and regulation of the endocannabinoid system in human dendritic cells. |
2002 |
Eur. J. Biochem. |
pmid:12153574
|
Gubellini P et al. |
Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission. |
2002 |
J. Neurosci. |
pmid:12177188
|
Romero J et al. |
Fatty acid amide hydrolase localization in the human central nervous system: an immunohistochemical study. |
2002 |
Brain Res. Mol. Brain Res. |
pmid:12008024
|
Kozak KR et al. |
15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist. |
2002 |
J. Biol. Chem. |
pmid:11956198
|
Sugiura T et al. |
Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. |
2002 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12052034
|
Fowler CJ and Jacobsson SO |
Cellular transport of anandamide, 2-arachidonoylglycerol and palmitoylethanolamide--targets for drug development? |
2002 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12052035
|
Högestätt ED and Zygmunt PM |
Cardiovascular pharmacology of anandamide. |
2002 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12052048
|
van der Stelt M et al. |
Acute neuronal injury, excitotoxicity, and the endocannabinoid system. |
2002 Oct-Dec |
Mol. Neurobiol. |
pmid:12428763
|
Jordà MA et al. |
The peripheral cannabinoid receptor Cb2, a novel oncoprotein, induces a reversible block in neutrophilic differentiation. |
2003 |
Blood |
pmid:12406867
|
Viganò D et al. |
Chronic morphine modulates the contents of the endocannabinoid, 2-arachidonoyl glycerol, in rat brain. |
2003 |
Neuropsychopharmacology |
pmid:12637958
|
Oka S et al. |
Ether-linked analogue of 2-arachidonoylglycerol (noladin ether) was not detected in the brains of various mammalian species. |
2003 |
J. Neurochem. |
pmid:12787057
|
Jorda MA et al. |
Identification, characterization, and function of a novel oncogene: the peripheral cannabinoid receptor Cb2. |
2003 |
Ann. N. Y. Acad. Sci. |
pmid:12799277
|
Walter L and Stella N |
Endothelin-1 increases 2-arachidonoyl glycerol (2-AG) production in astrocytes. |
2003 |
Glia |
pmid:12951660
|
Wallace MJ et al. |
The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12954810
|
Vannacci A et al. |
Nitric oxide modulates the inhibitory effect of cannabinoids on the immunological activation of guinea pig mast cells. |
2003 |
Inflamm. Res. |
pmid:12755386
|
Kishimoto S et al. |
2-arachidonoylglycerol induces the migration of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism. |
2003 |
J. Biol. Chem. |
pmid:12711605
|
Maccarrone M et al. |
Activation of human platelets by 2-arachidonoylglycerol is enhanced by serotonin. |
2003 |
Thromb. Haemost. |
pmid:12574815
|
Walter L et al. |
Nonpsychotropic cannabinoid receptors regulate microglial cell migration. |
2003 |
J. Neurosci. |
pmid:12598628
|
Fride E et al. |
Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. |
2003 |
Eur. J. Pharmacol. |
pmid:12568912
|
Fowler CJ et al. |
Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. |
2003 |
Biochem. Pharmacol. |
pmid:12948856
|
Patel S et al. |
Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12808005
|
Watanabe S et al. |
n-3 Polyunsaturated fatty acid (PUFA) deficiency elevates and n-3 PUFA enrichment reduces brain 2-arachidonoylglycerol level in mice. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12878451
|
Hanus L et al. |
Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain. |
2003 |
Brain Res. |
pmid:12914975
|
Obata T et al. |
Simultaneous determination of endocannabinoids (arachidonylethanolamide and 2-arachidonylglycerol) and isoprostane (8-epiprostaglandin F2alpha) by gas chromatography-mass spectrometry-selected ion monitoring for medical samples. |
2003 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:12829006
|
Maccarrone M et al. |
Progesterone activates fatty acid amide hydrolase (FAAH) promoter in human T lymphocytes through the transcription factor Ikaros. Evidence for a synergistic effect of leptin. |
2003 |
J. Biol. Chem. |
pmid:12799380
|
Franklin A et al. |
Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility. |
2003 |
J. Neurosci. |
pmid:12944505
|
Liu J et al. |
Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor. |
2003 |
J. Biol. Chem. |
pmid:12949078
|
Derkinderen P et al. |
Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus. |
2003 |
J. Neurosci. |
pmid:12657697
|
Gaetani S et al. |
Anandamide hydrolysis: a new target for anti-anxiety drugs? |
2003 |
Trends Mol Med |
pmid:14604824
|
Maccarrone M et al. |
Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism. |
2003 |
J. Neurochem. |
pmid:12716433
|
Lépicier P et al. |
Endocannabinoids protect the rat isolated heart against ischaemia. |
2003 |
Br. J. Pharmacol. |
pmid:12813004
|
Bouchard JF et al. |
Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart. |
2003 |
Life Sci. |
pmid:12586223
|
McCarron RM et al. |
Antioxidant properties of the vasoactive endocannabinoid, 2-arachidonoyl glycerol (2-AG). |
2003 |
Acta Neurochir. Suppl. |
pmid:14753451
|
Higgs S et al. |
Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. |
2003 |
Psychopharmacology (Berl.) |
pmid:12447606
|
Bisogno T et al. |
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. |
2003 |
J. Cell Biol. |
pmid:14610053
|
Facchinetti F et al. |
Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide. |
2003 |
Glia |
pmid:12509806
|
Mechoulam R and Lichtman AH |
Neuroscience. Stout guards of the central nervous system. |
2003 |
Science |
pmid:14526067
|
Marsicano G et al. |
CB1 cannabinoid receptors and on-demand defense against excitotoxicity. |
2003 |
Science |
pmid:14526074
|
Kim J and Alger BE |
Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus. |
2004 |
Nat. Neurosci. |
pmid:15184902
|
Witting A et al. |
Endocannabinoids accumulate in spinal cord of SOD1 G93A transgenic mice. |
2004 |
J. Neurochem. |
pmid:15189359
|
Stanke-Labesque F et al. |
2-Arachidonoyl glycerol induces contraction of isolated rat aorta: role of cyclooxygenase-derived products. |
2004 |
Cardiovasc. Res. |
pmid:15194472
|
Oka S et al. |
2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils. |
2004 |
J. Leukoc. Biol. |
pmid:15316028
|
Nithipatikom K et al. |
2-arachidonoylglycerol: a novel inhibitor of androgen-independent prostate cancer cell invasion. |
2004 |
Cancer Res. |
pmid:15604240
|
González S et al. |
Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence. |
2004 |
Drug Alcohol Depend |
pmid:15099659
|
Valenti M et al. |
Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain. |
2004 |
Cell. Mol. Life Sci. |
pmid:15095014
|
Kishimoto S et al. |
2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells. |
2004 |
J. Biochem. |
pmid:15115777
|
Hájos N et al. |
Endocannabinoid transport tightly controls 2-arachidonoyl glycerol actions in the hippocampus: effects of low temperature and the transport inhibitor AM404. |
2004 |
Eur. J. Neurosci. |
pmid:15182306
|
Vannacci A et al. |
The endocannabinoid 2-arachidonylglycerol decreases the immunological activation of Guinea pig mast cells: involvement of nitric oxide and eicosanoids. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:15187170
|
Maestroni GJ |
The endogenous cannabinoid 2-arachidonoyl glycerol as in vivo chemoattractant for dendritic cells and adjuvant for Th1 response to a soluble protein. |
2004 |
FASEB J. |
pmid:15385435
|
Walter L et al. |
ATP induces a rapid and pronounced increase in 2-arachidonoylglycerol production by astrocytes, a response limited by monoacylglycerol lipase. |
2004 |
J. Neurosci. |
pmid:15371507
|
Dinh TP et al. |
RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol. |
2004 |
Mol. Pharmacol. |
pmid:15272052
|
Malorni W et al. |
Morphological evidence that 2-arachidonoylglycerol is a true agonist of human platelets. |
2004 |
Thromb. Haemost. |
pmid:15543349
|
Melis M et al. |
Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons. |
2004 |
J. Neurosci. |
pmid:15564588
|
Sugiura T et al. |
New perspectives in the studies on endocannabinoid and cannabis: 2-arachidonoylglycerol as a possible novel mediator of inflammation. |
2004 |
J. Pharmacol. Sci. |
pmid:15599096
|
Saario SM et al. |
Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes. |
2004 |
Biochem. Pharmacol. |
pmid:15013854
|
Alberich Jordà M et al. |
The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner. |
2004 |
Blood |
pmid:15039279
|
Witting A et al. |
P2X7 receptors control 2-arachidonoylglycerol production by microglial cells. |
2004 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:14976257
|
Carrier EJ et al. |
Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism. |
2004 |
Mol. Pharmacol. |
pmid:15044630
|
Golech SA et al. |
Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors. |
2004 |
Brain Res. Mol. Brain Res. |
pmid:15548432
|
Mukherjee S et al. |
Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors. |
2004 |
Eur. J. Pharmacol. |
pmid:15556131
|
Guo J and Ikeda SR |
Endocannabinoids modulate N-type calcium channels and G-protein-coupled inwardly rectifying potassium channels via CB1 cannabinoid receptors heterologously expressed in mammalian neurons. |
2004 |
Mol. Pharmacol. |
pmid:14978245
|
Piomelli D |
The endogenous cannabinoid system and the treatment of marijuana dependence. |
2004 |
Neuropharmacology |
pmid:15464150
|
Ghafouri N et al. |
Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. |
2004 |
Br. J. Pharmacol. |
pmid:15492019
|
Motobe T et al. |
Endogenous cannabinoids are candidates for lipid mediators of bone cement implantation syndrome. |
2004 |
Shock |
pmid:14676677
|
van der Stelt M et al. |
A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease. |
2005 |
FASEB J. |
pmid:15894565
|
Venderova K et al. |
Differential effects of endocannabinoids on [(3)H]-GABA uptake in the rat globus pallidus. |
2005 |
Exp. Neurol. |
pmid:15899265
|
Julien B et al. |
Antifibrogenic role of the cannabinoid receptor CB2 in the liver. |
2005 |
Gastroenterology |
pmid:15765409
|
Chen J et al. |
Finding of endocannabinoids in human eye tissues: implications for glaucoma. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15823551
|
Sipe JC et al. |
Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: possible risk for autoimmune disorders. |
2005 |
J. Leukoc. Biol. |
pmid:15845647
|
Jung KM et al. |
Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. |
2005 |
Mol. Pharmacol. |
pmid:16051747
|
Makara JK et al. |
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. |
2005 |
Nat. Neurosci. |
pmid:16116451
|
Secko D |
Analgesia through endogenous cannabinoids. |
2005 |
CMAJ |
pmid:16103504
|
Maejima T et al. |
Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum. |
2005 |
J. Neurosci. |
pmid:16033892
|
Panikashvili D et al. |
CB1 cannabinoid receptors are involved in neuroprotection via NF-kappa B inhibition. |
2005 |
J. Cereb. Blood Flow Metab. |
pmid:15729296
|
Gauthier KM et al. |
Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. |
2005 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:15528233
|
Gabbay E et al. |
Endocannabinoids and liver disease--review. |
2005 |
Liver Int. |
pmid:16162147
|
Vandevoorde S et al. |
Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:16181610
|
Ramos JA et al. |
Therapeutic potential of the endocannabinoid system in the brain. |
2005 |
Mini Rev Med Chem |
pmid:16026307
|