MeSH term | MeSH ID | Detail |
---|---|---|
Inflammation | D007249 | 119 associated lipids |
Pain | D010146 | 64 associated lipids |
Thinness | D013851 | 11 associated lipids |
2-Monoolein is a lipid of Glycerolipids (GL) class. The involved functions are known as Regulation, Binding (Molecular Function), Cytokinesis of the fertilized ovum, Signal Transduction and Drug Interactions. 2-monoolein often locates in Extracellular, Brain region, Membrane, Body tissue and Protoplasm. The associated genes with 2-Monoolein are Glucagon-Like Peptide 1, Homologous Gene, LIPG gene and Serum Albumin. The related lipids are oleoylethanolamide, stearoylethanolamide, Fatty Acids, Nonesterified, Fatty Acids, Unsaturated and linoleoyl ethanolamide. The related experimental models are Knock-out.
To understand associated biological information of 2-Monoolein, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 2-Monoolein
MeSH term | MeSH ID | Detail |
---|---|---|
Inflammation | D007249 | 119 associated lipids |
Pain | D010146 | 64 associated lipids |
Thinness | D013851 | 11 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Ulloa NM and Deutsch DG | Assessment of a spectrophotometric assay for monoacylglycerol lipase activity. | 2010 | AAPS J | pmid:20186507 |
van Mechelen JB et al. | Structures of mono-unsaturated triacylglycerols. V. The beta'(1)-2, beta'-3 and beta(2)-3 polymorphs of 1,3-dilauroyl-2-oleoylglycerol (LaOLa) from synchrotron and laboratory powder diffraction data. | 2008 | Acta Crystallogr., B | pmid:19029706 |
Mandøe MJ et al. | The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans. | 2015 | Am. J. Clin. Nutr. | pmid:26178726 |
Syed SK et al. | Regulation of GPR119 receptor activity with endocannabinoid-like lipids. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:23074242 |
Vandevoorde S et al. | Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16181610 |
Gantayet A et al. | Endocannabinoids and diacylglycerol kinase activity. | 2011 | Biochim. Biophys. Acta | pmid:21194521 |
Hassing HA et al. | Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor. | 2016 | Biofactors | pmid:27297962 |
Kleberg K et al. | Evaluation of the immediate vascular stability of lipoprotein lipase-generated 2-monoacylglycerol in mice. | Biofactors | pmid:25359532 | |
Woodhams SG et al. | Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. | 2012 | Br. J. Pharmacol. | pmid:22924700 |