2-Monoolein

2-Monoolein is a lipid of Glycerolipids (GL) class. The involved functions are known as Regulation, Binding (Molecular Function), Cytokinesis of the fertilized ovum, Signal Transduction and Drug Interactions. 2-monoolein often locates in Extracellular, Brain region, Membrane, Body tissue and Protoplasm. The associated genes with 2-Monoolein are Glucagon-Like Peptide 1, Homologous Gene, LIPG gene and Serum Albumin. The related lipids are oleoylethanolamide, stearoylethanolamide, Fatty Acids, Nonesterified, Fatty Acids, Unsaturated and linoleoyl ethanolamide. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of 2-Monoolein, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2-Monoolein?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-Monoolein

PubChem Associated disorders and diseases

What pathways are associated with 2-Monoolein

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2-Monoolein?

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What functions are associated with 2-Monoolein?


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What lipids are associated with 2-Monoolein?

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What genes are associated with 2-Monoolein?

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What common seen animal models are associated with 2-Monoolein?

Knock-out

Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with 2-Monoolein

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Authors Title Published Journal PubMed Link
Hanlon EC et al. Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol. 2016 Sleep pmid:26612385
Murataeva N et al. Where's my entourage? The curious case of 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol. 2016 Pharmacol. Res. pmid:27117667
Roberts CJ et al. Swim stress differentially affects limbic contents of 2-arachidonoylglycerol and 2-oleoylglycerol. 2012 Neuroscience pmid:22192839
Rademacher DJ et al. Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice. 2008 Neuropharmacology pmid:17675104
Nomura DK et al. Activation of the endocannabinoid system by organophosphorus nerve agents. 2008 Nat. Chem. Biol. pmid:18438404
Martin GG et al. Female Mice are Resistant to Fabp1 Gene Ablation-Induced Alterations in Brain Endocannabinoid Levels. 2016 Lipids pmid:27450559
Cisneros JA et al. Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. 2007 J. Med. Chem. pmid:17764163
Pastor A et al. Analysis of ECs and related compounds in plasma: artifactual isomerization and ex vivo enzymatic generation of 2-MGs. 2014 J. Lipid Res. pmid:24610889
Navia-Paldanius D et al. Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12). 2012 J. Lipid Res. pmid:22969151
Hansen KB et al. 2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. 2011 J. Clin. Endocrinol. Metab. pmid:21778222