noladin ether

Noladin ether is a lipid of Glycerolipids (GL) class. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity and Competitive inhibition. Noladin ether often locates in Synaptosomes and Tissue membrane. The associated genes with Noladin Ether are IMPACT gene. The related lipids are noladin ether and Fatty Alcohols.

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Introduction

To understand associated biological information of noladin ether, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with noladin ether?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with noladin ether

PubChem Associated disorders and diseases

What pathways are associated with noladin ether

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PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with noladin ether?

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What functions are associated with noladin ether?


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What lipids are associated with noladin ether?

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What genes are associated with noladin ether?

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What common seen animal models are associated with noladin ether?

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Jones EK and Kirkham TC Noladin ether, a putative endocannabinoid, enhances motivation to eat after acute systemic administration in rats. 2012 Br. J. Pharmacol. pmid:22309979
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Laine K et al. Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid. 2002 Invest. Ophthalmol. Vis. Sci. pmid:12356827
Njie YF et al. Noladin ether acts on trabecular meshwork cannabinoid (CB1) receptors to enhance aqueous humor outflow facility. 2006 Invest. Ophthalmol. Vis. Sci. pmid:16639008
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Juntunen J et al. Synthesis, in vitro evaluation, and intraocular pressure effects of water-soluble prodrugs of endocannabinoid noladin ether. 2003 J. Med. Chem. pmid:14584958
Oka S et al. Ether-linked analogue of 2-arachidonoylglycerol (noladin ether) was not detected in the brains of various mammalian species. 2003 J. Neurochem. pmid:12787057
Shoemaker JL et al. Agonist-directed trafficking of response by endocannabinoids acting at CB2 receptors. 2005 J. Pharmacol. Exp. Ther. pmid:16081674
Shoemaker JL et al. The endocannabinoid noladin ether acts as a full agonist at human CB2 cannabinoid receptors. 2005 J. Pharmacol. Exp. Ther. pmid:15901805
Shimizu T et al. Stimulatory and inhibitory roles of brain 2-arachidonoylglycerol in bombesin-induced central activation of adrenomedullary outflow in rats. 2013 J. Pharmacol. Sci. pmid:23386378
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Guo J and Ikeda SR Endocannabinoids modulate N-type calcium channels and G-protein-coupled inwardly rectifying potassium channels via CB1 cannabinoid receptors heterologously expressed in mammalian neurons. 2004 Mol. Pharmacol. pmid:14978245
Kumar A and Song ZH CB1 cannabinoid receptor-mediated changes of trabecular meshwork cellular properties. 2006 Mol. Vis. pmid:16617296
Páldy E et al. CB(2) cannabinoid receptor antagonist SR144528 decreases mu-opioid receptor expression and activation in mouse brainstem: role of CB(2) receptor in pain. 2008 Neurochem. Int. pmid:18804501
Páldyová E et al. Noladin ether, a putative endocannabinoid, inhibits mu-opioid receptor activation via CB2 cannabinoid receptors. 2008 Neurochem. Int. pmid:17698254
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Izumi Y and Zorumski CF NMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depression. 2012 Neuropsychopharmacology pmid:21993209
Milton NG Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. 2002 Neurosci. Lett. pmid:12384227
Maison P et al. BDNF regulates neuronal sensitivity to endocannabinoids. 2009 Neurosci. Lett. pmid:19818836
Deshmukh RR and Sharma PL Stimulation of accumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats. 2012 Pharmacol. Res. pmid:22728691
Iannotti FA et al. The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:24927567
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Nithipatikom K et al. Anti-proliferative effect of a putative endocannabinoid, 2-arachidonylglyceryl ether in prostate carcinoma cells. 2011 Prostaglandins Other Lipid Mediat. pmid:21167293