| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
Total
3
Punicic acid
Punicic acid is a lipid of Fatty Acyls (FA) class. Punicic acid is associated with abnormalities such as Dental caries and Decompression Sickness. The involved functions are known as Anabolism, Binding (Molecular Function), metaplastic cell transformation, Stereochemistry and Oxidants. Punicic acid often locates in Back. The associated genes with Punicic acid are MUT gene, FANCD2 wt Allele, IMPACT gene and SPAG5 gene. The related lipids are Fatty Acids, calendic acid, punicic acid and catalpic acid.
Cross Reference
Introduction
To understand associated biological information of Punicic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Punicic acid?
Punicic acid is suspected in Decompression Sickness and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Punicic acid
PubChem Associated disorders and diseases
What pathways are associated with Punicic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Punicic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Punicic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Punicic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Punicic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Punicic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Punicic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| de Melo IL et al. | Incorporation and effects of punicic acid on muscle and adipose tissues of rats. | 2016 | Lipids Health Dis | pmid:26922800 |
| Lu P et al. | Modeling-Enabled Characterization of Novel NLRX1 Ligands. | 2015 | PLoS ONE | pmid:26714018 |
| Wang L et al. | Luteolin, ellagic acid and punicic acid are natural products that inhibit prostate cancer metastasis. | 2014 | Carcinogenesis | pmid:25023990 |
| Costantini S et al. | Potential anti-inflammatory effects of the hydrophilic fraction of pomegranate (Punica granatum L.) seed oil on breast cancer cell lines. | 2014 | Molecules | pmid:24962397 |
| Huang K et al. | Epoxy monomers derived from tung oil fatty acids and its regulable thermosets cured in two synergistic ways. | 2014 | Biomacromolecules | pmid:24484324 |
| Zhuo RJ et al. | Α-eleostearic acid inhibits growth and induces apoptosis in breast cancer cells via HER2/HER3 signaling. | 2014 | Mol Med Rep | pmid:24425042 |
| Gasmi J and Thomas Sanderson J | Jacaric acid and its octadecatrienoic acid geoisomers induce apoptosis selectively in cancerous human prostate cells: a mechanistic and 3-D structure-activity study. | 2013 | Phytomedicine | pmid:23453308 |
| Saha SS and Ghosh M | Protective effect of conjugated linolenic acid isomers present in vegetable oils against arsenite-induced renal toxicity in rat model. | 2013 | Nutrition | pmid:23422533 |
| Schneider AC et al. | Uptake of conjugated linolenic acids and conversion to cis-9, trans-11-or trans-9, trans-11-conjugated linoleic acids in Caco-2 cells. | 2013 | Br. J. Nutr. | pmid:22472138 |
| Pastor S et al. | Molecular properties of the class III subfamily of acyl-coenyzme A binding proteins from tung tree (Vernicia fordii). | 2013 | Plant Sci. | pmid:23415331 |
| Obitsu S et al. | Eleostearic acid induces RIP1-mediated atypical apoptosis in a kinase-independent manner via ERK phosphorylation, ROS generation and mitochondrial dysfunction. | 2013 | Cell Death Dis | pmid:23788031 |
| Serveau-Avesque C et al. | Development of a high-throughput assay for measuring lipase activity using natural triacylglycerols coated on microtiter plates. | 2013 | Analyst | pmid:23851449 |
| de Sousa RS et al. | Effects of α-eleostearic acid on asolectin liposomes dynamics: relevance to its antioxidant activity. | 2013 | Bioorg. Chem. | pmid:24076476 |
| Çam M et al. | Enrichment of functional properties of ice cream with pomegranate by-products. | 2013 | J. Food Sci. | pmid:24102443 |
| Cui QQ et al. | Expression analysis of VfDGAT2 in various tissues of the tung tree and in transgenic yeast. | 2013 | Genet. Mol. Res. | pmid:24391002 |
| Spilmont M et al. | Pomegranate seed oil prevents bone loss in a mice model of osteoporosis, through osteoblastic stimulation, osteoclastic inhibition and decreased inflammatory status. | 2013 | J. Nutr. Biochem. | pmid:23953990 |
| Zhang T et al. | Growth inhibition and apoptotic effect of alpha-eleostearic acid on human breast cancer cells. | 2012 | J Nat Med | pmid:21691836 |
| Saha SS et al. | Comparative study of hypocholesterolemic and hypolipidemic effects of conjugated linolenic acid isomers against induced biochemical perturbations and aberration in erythrocyte membrane fluidity. | 2012 | Eur J Nutr | pmid:21814874 |
| Chen PH et al. | Bitter melon seed oil-attenuated body fat accumulation in diet-induced obese mice is associated with cAMP-dependent protein kinase activation and cell death in white adipose tissue. | 2012 | J. Nutr. | pmid:22623391 |
| Sun Z et al. | Beta-eleostearic acid induce apoptosis in T24 human bladder cancer cells through reactive oxygen species (ROS)-mediated pathway. | 2012 | Prostaglandins Other Lipid Mediat. | pmid:22609276 |
| Pal M and Ghosh M | Studies on comparative efficacy of α-linolenic acid and α-eleostearic acid on prevention of organic mercury-induced oxidative stress in kidney and liver of rat. | 2012 | Food Chem. Toxicol. | pmid:22269903 |
| Lai CS et al. | Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPARγ and C/EBPs and modulation of SIRT-1, AMPK, and FoxO pathways. | 2012 | J. Agric. Food Chem. | pmid:22224971 |
| Saha SS and Ghosh M | Antioxidant and anti-inflammatory effect of conjugated linolenic acid isomers against streptozotocin-induced diabetes. | 2012 | Br. J. Nutr. | pmid:22182422 |
| Chou YC et al. | cis-9, trans-11, trans-13-Conjugated linolenic acid induces apoptosis and sustained ERK phosphorylation in 3T3-L1 preadipocytes. | 2012 | Nutrition | pmid:22465903 |
| Rawat R et al. | Conjugated fatty acid synthesis: residues 111 and 115 influence product partitioning of Momordica charantia conjugase. | 2012 | J. Biol. Chem. | pmid:22451660 |
| Pal M and Ghosh M | Prophylactic effect of α-linolenic acid and α-eleostearic acid against MeHg induced oxidative stress, DNA damage and structural changes in RBC membrane. | 2012 | Food Chem. Toxicol. | pmid:22683484 |
| Rocha A et al. | Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer. | 2012 | Breast Cancer Res. Treat. | pmid:23065001 |
| Vroegrijk IO et al. | Pomegranate seed oil, a rich source of punicic acid, prevents diet-induced obesity and insulin resistance in mice. | 2011 | Food Chem. Toxicol. | pmid:21440024 |
| Saha SS and Ghosh M | Antioxidant effect of vegetable oils containing conjugated linolenic acid isomers against induced tissue lipid peroxidation and inflammation in rat model. | 2011 | Chem. Biol. Interact. | pmid:21382362 |
| Bassaganya-Riera J et al. | Activation of PPARγ and δ by dietary punicic acid ameliorates intestinal inflammation in mice. | 2011 | Br. J. Nutr. | pmid:21736821 |
| Modaresi J et al. | Short communication: effects of supplementation with pomegranate seed pulp on concentrations of conjugated linoleic acid and punicic acid in goat milk. | 2011 | J. Dairy Sci. | pmid:21787942 |
| Lewis SN et al. | Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ. | 2011 | PLoS ONE | pmid:21904603 |
| Yang P et al. | Mining the bitter melon (momordica charantia l.) seed transcriptome by 454 analysis of non-normalized and normalized cDNA populations for conjugated fatty acid metabolism-related genes. | 2010 | BMC Plant Biol. | pmid:21080948 |
| Moon HS et al. | Alpha-eleostearic acid suppresses proliferation of MCF-7 breast cancer cells via activation of PPARgamma and inhibition of ERK 1 / 2. | 2010 | Cancer Sci. | pmid:19917060 |
| Eom JM et al. | Alpha-eleostearic acid induces autophagy-dependent cell death through targeting AKT/mTOR and ERK1/2 signal together with the generation of reactive oxygen species. | 2010 | Biochem. Biophys. Res. Commun. | pmid:19951696 |
| Kondo K et al. | Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition. | 2010 | J. Biol. Chem. | pmid:20177052 |
| Grossmann ME et al. | Punicic acid is an omega-5 fatty acid capable of inhibiting breast cancer proliferation. | 2010 | Int. J. Oncol. | pmid:20043077 |
| Saha SS and Ghosh M | Ameliorative role of conjugated linolenic acid isomers against oxidative DNA damage induced by sodium arsenite in rat model. | 2010 | Food Chem. Toxicol. | pmid:20851731 |
| Yuan G et al. | Incorporation and metabolism of punicic acid in healthy young humans. | 2009 | Mol Nutr Food Res | pmid:19753607 |
| Yuan GF et al. | Punicic acid from Trichosanthes kirilowii seed oil is rapidly metabolized to conjugated linoleic acid in rats. | 2009 | J Med Food | pmid:19459746 |
| Boussetta T et al. | Punicic acid a conjugated linolenic acid inhibits TNFalpha-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats. | 2009 | PLoS ONE | pmid:19649246 |
| Saha SS and Ghosh M | Comparative study of antioxidant activity of alpha-eleostearic acid and punicic acid against oxidative stress generated by sodium arsenite. | 2009 | Food Chem. Toxicol. | pmid:19619603 |
| Hontecillas R et al. | Activation of PPAR gamma and alpha by punicic acid ameliorates glucose tolerance and suppresses obesity-related inflammation. | 2009 | J Am Coll Nutr | pmid:19828904 |
| Kobori M et al. | Alpha-eleostearic acid and its dihydroxy derivative are major apoptosis-inducing components of bitter gourd. | 2008 | J. Agric. Food Chem. | pmid:18959405 |
| Tsuzuki T and Kawakami Y | Tumor angiogenesis suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via peroxisome proliferator-activated receptor gamma. | 2008 | Carcinogenesis | pmid:18174233 |
| Koba K et al. | Genetically modified rapeseed oil containing cis-9,trans-11,cis-13-octadecatrienoic acid affects body fat mass and lipid metabolism in mice. | 2007 | J. Agric. Food Chem. | pmid:17394332 |
| Cao Y et al. | Re-characterization of three conjugated linolenic acid isomers by GC-MS and NMR. | 2007 | Chem. Phys. Lipids | pmid:17204261 |
| Suzuki R et al. | Catalpa seed oil rich in 9t,11t,13c-conjugated linolenic acid suppresses the development of colonic aberrant crypt foci induced by azoxymethane in rats. | 2006 | Oncol. Rep. | pmid:17016582 |
| Shockey JM et al. | Tung tree DGAT1 and DGAT2 have nonredundant functions in triacylglycerol biosynthesis and are localized to different subdomains of the endoplasmic reticulum. | 2006 | Plant Cell | pmid:16920778 |
| Kitamura Y et al. | Lack of chemopreventive effects of alpha-eleostearic acid on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary and colon carcinogenesis in female Sprague-Dawley rats. | 2006 | Food Chem. Toxicol. | pmid:16122863 |