| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Amyloidosis | D000686 | 4 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Guo Q et al. | Highly sensitive method for the quantification of trans-linolenic acid isomers in trilinolenin of edible oils using an ionic liquid capillary column. | 2017 | J. Sci. Food Agric. | pmid:28369919 |
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| Yadav S et al. | Comparative efficacy of alpha-linolenic acid and gamma-linolenic acid to attenuate valproic acid-induced autism-like features. | 2017 | J. Physiol. Biochem. | pmid:27878518 |
| Mao Y et al. | Chemical Composition Analysis, Sensory, and Feasibility Study of Tree Peony Seed. | 2017 | J. Food Sci. | pmid:28135396 |
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| Bentrad N et al. | Identification and evaluation of antibacterial agents present in lipophilic fractions isolated from sub-products of Phoenix dactilyfera. | 2017 | Nat. Prod. Res. | pmid:28403631 |
| Mirabi P et al. | The role of fatty acids on ICSI outcomes: a prospective cohort study. | 2017 | Lipids Health Dis | pmid:28109274 |
| Veselinovic M et al. | Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. | 2017 | Nutrients | pmid:28346333 |
| Oki E et al. | Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil. | 2017 | Br. J. Nutr. | pmid:28633686 |
| Angkasa D et al. | Inadequate dietary α-linolenic acid intake among Indonesian pregnant women is associated with lower newborn weights in urban Jakarta. | 2017 | Asia Pac J Clin Nutr | pmid:28625031 |
| Jovanovski E et al. | The effect of alpha-linolenic acid on glycemic control in individuals with type 2 diabetes: A systematic review and meta-analysis of randomized controlled clinical trials. | 2017 | Medicine (Baltimore) | pmid:28538363 |
| Zheng JS et al. | Genetic Risk Score of Nine Type 2 Diabetes Risk Variants that Interact with Erythrocyte Phospholipid Alpha-Linolenic Acid for Type 2 Diabetes in Chinese Hans: A Case-Control Study. | 2017 | Nutrients | pmid:28398239 |
| Lodolini EM et al. | Oil Characteristics of Four Palestinian Olive Varieties. | 2017 | J Oleo Sci | pmid:28381771 |
| Lefort N et al. | Dietary Buglossoides Arvensis Oil Increases Circulating n-3 Polyunsaturated Fatty Acids in a Dose-Dependent Manner and Enhances Lipopolysaccharide-Stimulated Whole Blood Interleukin-10-A Randomized Placebo-Controlled Trial. | 2017 | Nutrients | pmid:28287415 |
| Marmon S et al. | Two Acyltransferases Contribute Differently to Linolenic Acid Levels in Seed Oil. | 2017 | Plant Physiol. | pmid:28235891 |
| Ando Y et al. | Alpha Linolenic Acid-enriched Diacylglycerol Consumption Enhances Dietary Fat Oxidation in Healthy Subjects: A Randomized Double-blind Controlled Trial. | 2017 | J Oleo Sci | pmid:28154349 |
| GarcÃa-Vico L et al. | Volatile Compound Profiling by HS-SPME/GC-MS-FID of a Core Olive Cultivar Collection as a Tool for Aroma Improvement of Virgin Olive Oil. | 2017 | Molecules | pmid:28098834 |
| Senftleber NK et al. | Marine Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials. | 2017 | Nutrients | pmid:28067815 |
| Du H et al. | Extraction and the Fatty Acid Profile of Rosa acicularis Seed Oil. | 2017 | J Oleo Sci | pmid:29129896 |
| Park H et al. | Towards the development of a sustainable soya bean-based feedstock for aquaculture. | 2017 | Plant Biotechnol. J. | pmid:27496594 |
| Wang XH et al. | High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2. | 2017 | Front Pharmacol | pmid:28555106 |
| Kim H et al. | Association between maternal intake of n-6 to n-3 fatty acid ratio during pregnancy and infant neurodevelopment at 6 months of age: results of the MOCEH cohort study. | 2017 | Nutr J | pmid:28420388 |
| Alsharari ZD et al. | Serum Fatty Acids, Desaturase Activities and Abdominal Obesity - A Population-Based Study of 60-Year Old Men and Women. | 2017 | PLoS ONE | pmid:28125662 |
| Muralikumar S et al. | Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties. | 2017 | Lipids Health Dis | pmid:28109294 |
| Leroy C et al. | Fatty acid-binding protein3 expression in BeWo cells, a human placental choriocarcinoma cell line. | 2017 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:28515017 |
| Matravadia S et al. | LA and ALA prevent glucose intolerance in obese male rats without reducing reactive lipid content, but cause tissue-specific changes in fatty acid composition. | 2016 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:26764053 |
| López-Luna P et al. | Fate of orally administered radioactive fatty acids in the late-pregnant rat. | 2016 | Am. J. Physiol. Endocrinol. Metab. | pmid:26714850 |
| Li T et al. | Defense priming by non-jasmonate producing fatty acids in maize (Zea mays). | 2016 | Plant Signal Behav | pmid:27763804 |
| Kjær MA et al. | Regulation of the Omega-3 Fatty Acid Biosynthetic Pathway in Atlantic Salmon Hepatocytes. | 2016 | PLoS ONE | pmid:27973547 |
| Cao X et al. | Transcriptional Responses and Gentiopicroside Biosynthesis in Methyl Jasmonate-Treated Gentiana macrophylla Seedlings. | 2016 | PLoS ONE | pmid:27851826 |
| Wolters M et al. | Associations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents - Results from the IDEFICS/I.Family Cohort. | 2016 | PLoS ONE | pmid:27806134 |
| Demorest ZL et al. | Direct stacking of sequence-specific nuclease-induced mutations to produce high oleic and low linolenic soybean oil. | 2016 | BMC Plant Biol. | pmid:27733139 |
| Li XZ et al. | Dietary linseed oil with or without malate increases conjugated linoleic acid and oleic acid in milk fat and and gene expression in mammary gland and milk somatic cells of lactating goats. | 2016 | J. Anim. Sci. | pmid:27695785 |
| Lee Y et al. | Alpha-linolenic acid treatment during oocyte maturation enhances embryonic development by influencing mitogen-activated protein kinase activity and intraoocyte glutathione content in pigs. | 2016 | J. Anim. Sci. | pmid:27695771 |
| Chen T et al. | Perilla Oil Supplementation Ameliorates High-Fat/High-Cholesterol Diet Induced Nonalcoholic Fatty Liver Disease in Rats via Enhanced Fecal Cholesterol and Bile Acid Excretion. | 2016 | Biomed Res Int | pmid:27642591 |
| Masoko P et al. | Isolation of alpha-linolenic acid from Sutherlandia frutescens and its inhibition of Mycobacterium tuberculosis' shikimate kinase enzyme. | 2016 | BMC Complement Altern Med | pmid:27639973 |
| Devassy JG et al. | Omega-3 Polyunsaturated Fatty Acids and Oxylipins in Neuroinflammation and Management of Alzheimer Disease. | 2016 | Adv Nutr | pmid:27633106 |
| Nuez-OrtÃn WG et al. | Preliminary Validation of a High Docosahexaenoic Acid (DHA) and -Linolenic Acid (ALA) Dietary Oil Blend: Tissue Fatty Acid Composition and Liver Proteome Response in Atlantic Salmon (Salmo salar) Smolts. | 2016 | PLoS ONE | pmid:27556399 |
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| Carotenuto F et al. | Dietary Flaxseed Mitigates Impaired Skeletal Muscle Regeneration: in Vivo, in Vitro and in Silico Studies. | 2016 | Int J Med Sci | pmid:26941581 |
| Dote S et al. | Effects of Triacylglycerol Molecular Species on the Oxidation Behavior of Oils Containing α-Linolenic Acid. | 2016 | J Oleo Sci | pmid:26935948 |
| Heskey CE et al. | Adipose tissue α-linolenic acid is inversely associated with insulin resistance in adults. | 2016 | Am. J. Clin. Nutr. | pmid:26912497 |
| Zhao N et al. | α-Linolenic acid increases the G0/G1 switch gene 2 mRNA expression in peripheral blood mononuclear cells from obese patients: a pilot study. | 2016 | Lipids Health Dis | pmid:26912161 |
| Taha AY et al. | Threshold changes in rat brain docosahexaenoic acid incorporation and concentration following graded reductions in dietary alpha-linolenic acid. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:26869088 |
| Moriyama R et al. | Long-chain unsaturated fatty acids reduce the transcriptional activity of the rat follicle-stimulating hormone β-subunit gene. | 2016 | J. Reprod. Dev. | pmid:26853521 |
| Deng Q et al. | Single frequency intake of α-linolenic acid rich phytosterol esters attenuates atherosclerosis risk factors in hamsters fed a high fat diet. | 2016 | Lipids Health Dis | pmid:26843021 |
| Gómez-Cortés P et al. | Novel characterisation of minor α-linolenic acid isomers in linseed oil by gas chromatography and covalent adduct chemical ionisation tandem mass spectrometry. | 2016 | Food Chem | pmid:26830571 |
| Venäläinen TM et al. | Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. | 2016 | Am. J. Clin. Nutr. | pmid:27581473 |
| Sala-Vila A et al. | Dietary α-Linolenic Acid, Marine ω-3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvención con DIeta MEDiterránea (PREDIMED) Study. | 2016 | J Am Heart Assoc | pmid:26813890 |
| Sakayori N et al. | Maternal Nutritional Imbalance between Linoleic Acid and Alpha-Linolenic Acid Increases Offspring's Anxious Behavior with a Sex-Dependent Manner in Mice. | 2016 | Tohoku J. Exp. Med. | pmid:27558477 |