alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Hearing Loss, High-Frequency D006316 1 associated lipids
Aging, Premature D019588 1 associated lipids
Night Blindness D009755 1 associated lipids
Stomatitis, Aphthous D013281 1 associated lipids
Conjunctivitis, Allergic D003233 1 associated lipids
Sebaceous Gland Neoplasms D012626 2 associated lipids
Otorhinolaryngologic Neoplasms D010039 2 associated lipids
Spinal Cord Ischemia D020760 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Dyskinesias D020820 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Hussey HJ and Tisdale MJ Mechanism of the anti-tumour effect of 2,3,5-trimethyl-6-(3-pyridylmethyl) 1,4-benzoquinone (CV-6504). 1997 Br. J. Cancer pmid:9062405
Oh-hashi K et al. Reevaluation of the effect of a high alpha-linolenate and a high linoleate diet on antigen-induced antibody and anaphylactic responses in mice. 1997 Biol. Pharm. Bull. pmid:9084876
Nishizaki T et al. Short-term depression and long-term enhancement of ACh-gated channel currents induced by linoleic and linolenic acid. 1997 Brain Res. pmid:9099812
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Vinggaard AM et al. Arf and RhoA regulate both the cytosolic and the membrane-bound phospholipase D from human placenta. 1997 Cell. Signal. pmid:9113419
Harris WS n-3 fatty acids and serum lipoproteins: human studies. 1997 Am. J. Clin. Nutr. pmid:9129504
Wagner W and Nootbaar-Wagner U Prophylactic treatment of migraine with gamma-linolenic and alpha-linolenic acids. 1997 Cephalalgia pmid:9137851
Sravan Kumar G and Das UN Cytotoxic action of alpha-linolenic and eicosapentaenoic acids on myeloma cells in vitro. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9150374
Koga T et al. Linoleic and alpha-linolenic acids differently modify the effects of elaidic acid on polyunsaturated fatty acid metabolism and some immune indices in rats. 1997 Br. J. Nutr. pmid:9155511
Sugihara N et al. Cytotoxicity of food preservatives in cultured rat hepatocytes loaded with linolenic acid. 1997 Toxicology pmid:9160106
Smith GM and Isopenko A Effect of doses of protected polyunsaturated fatty acids on indicators of selenium status of sheep. 1997 Jan-Feb Res. Vet. Sci. pmid:9160431
Hardwick SJ et al. Toxicity of polyunsaturated fatty acid esters for human monocyte-macrophages: the anomalous behaviour of cholesteryl linolenate. 1997 Free Radic. Res. pmid:9167940
Guesnet P et al. Modifying the n-3 fatty acid content of the maternal diet to determine the requirements of the fetal and suckling rat. 1997 Lipids pmid:9168459
Spitzer V et al. Structure analysis of an allene-containing estolide tetraester triglyceride in the seed oil of Sebastiana commersoniana (Euphorbiaceae). 1997 Lipids pmid:9168462
Jeffery NM et al. Effects of variations in the proportions of saturated, monounsaturated and polyunsaturated fatty acids in the rat diet on spleen lymphocyte functions. 1997 Br. J. Nutr. pmid:9175999
Harvei S et al. Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer. 1997 Int. J. Cancer pmid:9178806
Kokura S et al. Efficacy of hyperthermia and polyunsaturated fatty acids on experimental carcinoma. 1997 Cancer Res. pmid:9187121
Yehuda S et al. Essential fatty acid preparation improves biochemical and cognitive functions in experimental allergic encephalomyelitis rats. 1997 Eur. J. Pharmacol. pmid:9203563
Kelso KA et al. Effects of dietary supplementation with alpha-linolenic acid on the phospholipid fatty acid composition and quality of spermatozoa in cockerel from 24 to 72 weeks of age. 1997 J. Reprod. Fertil. pmid:9227357
Hisha H et al. Isolation and identification of hematopoietic stem cell-stimulating substances from Kampo (Japanese herbal) medicine, Juzen-taiho-to. 1997 Blood pmid:9242532