| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Amyloidosis | D000686 | 4 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Decsi T et al. | Polyunsaturated fatty acids in plasma and erythrocyte membrane lipids of diabetic children. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12401433 |
| Kratz M et al. | The impact of dietary fat composition on serum leptin concentrations in healthy nonobese men and women. | 2002 | J. Clin. Endocrinol. Metab. | pmid:12414865 |
| Bowen RA and Clandinin MT | Dietary low linolenic acid compared with docosahexaenoic acid alter synaptic plasma membrane phospholipid fatty acid composition and sodium-potassium ATPase kinetics in developing rats. | 2002 | J. Neurochem. | pmid:12421348 |
| Sanderson P et al. | UK Food Standards Agency alpha-linolenic acid workshop report. | 2002 | Br. J. Nutr. | pmid:12425738 |
| Kris-Etherton PM et al. | Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. | 2002 | Circulation | pmid:12438303 |
| Lanzmann-Petithory D et al. | Primary prevention of cardiovascular diseases by alpha-linolenic acid. | 2002 | Am. J. Clin. Nutr. | pmid:12450919 |
| Acar N et al. | FA composition of plasma, red blood cell, and liver phospholipids of newborn piglets fed trans isomers of alpha-linolenic acid. | 2002 | Lipids | pmid:12458619 |
| Simopoulos AP | Omega-3 fatty acids in inflammation and autoimmune diseases. | 2002 | J Am Coll Nutr | pmid:12480795 |
| Fisher AJ et al. | The biochemical origin of pentenol emissions from wounded leaves. | 2003 | Phytochemistry | pmid:12482451 |
| Maillard V et al. | Interaction of dietary beta-carotene and alpha-linolenic acid: effect on promotion of experimental mammary tumours. | 2002 | IARC Sci. Publ. | pmid:12484221 |
| López-López A et al. | Fatty acid and sn-2 fatty acid composition in human milk from Granada (Spain) and in infant formulas. | 2002 | Eur J Clin Nutr | pmid:12494309 |
| Briscoe CP et al. | The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. | 2003 | J. Biol. Chem. | pmid:12496284 |
| Liu YC and Wu SN | Block of erg current by linoleoylamide, a sleep-inducing agent, in pituitary GH3 cells. | 2003 | Eur. J. Pharmacol. | pmid:12498905 |
| Takemura N et al. | Dietary, but not topical, alpha-linolenic acid suppresses UVB-induced skin injury in hairless mice when compared with linoleic acids. | 2002 | Photochem. Photobiol. | pmid:12511046 |
| Scorolli L et al. | [Photodynamic therapy for age related macular degeneration with and without antioxidants]. | 2002 | Can. J. Ophthalmol. | pmid:12518724 |
| Lemaitre RN et al. | n-3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study. | 2003 | Am. J. Clin. Nutr. | pmid:12540389 |
| Innis SM and Elias SL | Intakes of essential n-6 and n-3 polyunsaturated fatty acids among pregnant Canadian women. | 2003 | Am. J. Clin. Nutr. | pmid:12540410 |
| Vos E and Cunnane SC | Alpha-linolenic acid, linoleic acid, coronary artery disease, and overall mortality. | 2003 | Am. J. Clin. Nutr. | pmid:12540417 |
| Suzuki M et al. | Endogenous alpha-ketol linolenic acid levels in short day-induced cotyledons are closely related to flower induction in Pharbitis nil. | 2003 | Plant Cell Physiol. | pmid:12552145 |
| Ghafoorunissa A et al. | Effects of dietary alpha-linolenic acid from blended oils on biochemical indices of coronary heart disease in Indians. | 2002 | Lipids | pmid:12558058 |
| Kotarsky K et al. | A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12565875 |
| Ascherio A | Epidemiologic studies on dietary fats and coronary heart disease. | 2002 | Am. J. Med. | pmid:12566133 |
| Castelli F et al. | Biomimesis of linolenic acid transport through model lipidic membranes by differential scanning calorimetry. | 2003 | J. Agric. Food Chem. | pmid:12568537 |
| Saito M and Kubo K | Relationship between tissue lipid peroxidation and peroxidizability index after alpha-linolenic, eicosapentaenoic, or docosahexaenoic acid intake in rats. | 2003 | Br. J. Nutr. | pmid:12568661 |
| Tan X et al. | [Supercritical-CO2 fluid extraction of fatty oils from Perilla frutescens seeds and pharmacological study]. | 1999 | Zhong Yao Cai | pmid:12571915 |
| von Schacky C | The role of omega-3 fatty acids in cardiovascular disease. | 2003 | Curr Atheroscler Rep | pmid:12573200 |
| Bazinet RP et al. | Whole-body beta-oxidation of 18:2omega6 and 18:3omega3 in the pig varies markedly with weaning strategy and dietary 18:3omega3. | 2003 | J. Lipid Res. | pmid:12576513 |
| Chen J et al. | Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor. | 2002 | Nutr Cancer | pmid:12588699 |
| Tsydendambaev VD and Vereshchagin AG | Changes in triacylglycerol composition during ripening of sea buckthorn (Hippophaë rhamnoides L.) seeds. | 2003 | J. Agric. Food Chem. | pmid:12590468 |
| Kurowska EM et al. | Bioavailability of omega-3 essential fatty acids from perilla seed oil. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591004 |
| Araseki M et al. | Oxidative stability of polyunsaturated fatty acid in phosphatidylcholine liposomes. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12596850 |
| Yang X et al. | [Effects of silkworm pupa oil on serum lipids level and platelet function in rats]. | 2002 | Wei Sheng Yan Jiu | pmid:12600031 |
| Pawlosky RJ et al. | Effects of beef- and fish-based diets on the kinetics of n-3 fatty acid metabolism in human subjects. | 2003 | Am. J. Clin. Nutr. | pmid:12600844 |
| Sinclair AJ et al. | What is the role of alpha-linolenic acid for mammals? | 2002 | Lipids | pmid:12617463 |
| Wolff RL | Are trans isomers of alpha-linolenic acid of nutritional significance for certain populations? | 2002 | Lipids | pmid:12617467 |
| Suresh Y and Das UN | Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus. Effect of omega-3 fatty acids. | 2003 | Nutrition | pmid:12620523 |
| Itoh Y et al. | Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. | 2003 | Nature | pmid:12629551 |
| Adlof RO and List GR | Synthesis and analysis of symmetrical and nonsymmetrical disaturated/monounsaturated triacylglycerols. | 2003 | J. Agric. Food Chem. | pmid:12643679 |
| Tanaka A and Nishizaki T | The newly synthesized linoleic acid derivative FR236924 induces a long-lasting facilitation of hippocampal neurotransmission by targeting nicotinic acetylcholine receptors. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12643906 |
| Acar N et al. | Modification of the dopaminergic neurotransmitters in striatum, frontal cortex and hippocampus of rats fed for 21 months with trans isomers of alpha-linolenic acid. | 2003 | Neurosci. Res. | pmid:12657450 |
| Finnegan YE et al. | Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects. | 2003 | Am. J. Clin. Nutr. | pmid:12663273 |
| Djoussé L et al. | Dietary linolenic acid and carotid atherosclerosis: the National Heart, Lung, and Blood Institute Family Heart Study. | 2003 | Am. J. Clin. Nutr. | pmid:12663278 |
| Baylin A et al. | Adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction in Costa Rica. | 2003 | Circulation | pmid:12668490 |
| Bakshi A et al. | Gamma-linolenic acid therapy of human gliomas. | 2003 | Nutrition | pmid:12679162 |
| Eynard AR | Potential of essential fatty acids as natural therapeutic products for human tumors. | 2003 | Nutrition | pmid:12679177 |
| AbuGhazaleh AA et al. | Milk conjugated linoleic acid response to fish oil supplementation of diets differing in fatty acid profiles. | 2003 | J. Dairy Sci. | pmid:12703631 |
| Ichihara K and Suda Y | Lipid biosynthesis in developing perilla seeds. | 2003 | Phytochemistry | pmid:12711134 |
| Gueck T et al. | Effects of essential fatty acids on mediators of mast cells in culture. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12711248 |
| Steer P et al. | Endothelial vasodilatory function is related to the proportions of saturated fatty acids and alpha-linolenic acid in young men, but not in women. | 2003 | Eur. J. Clin. Invest. | pmid:12713452 |
| James MJ et al. | Metabolism of stearidonic acid in human subjects: comparison with the metabolism of other n-3 fatty acids. | 2003 | Am. J. Clin. Nutr. | pmid:12716664 |