alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Amyloidosis D000686 4 associated lipids
Aortic Diseases D001018 11 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Birth Weight D001724 23 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Zien CA et al. In vivo substrates and the contribution of the common phospholipase D, PLDalpha, to wound-induced metabolism of lipids in Arabidopsis. 2001 Biochim. Biophys. Acta pmid:11239826
Billeaud C et al. Effects of preterm infant formula supplementation with alpha-linolenic acid with a linoleate/alpha-linolenate ratio of 6: a multicentric study. 1997 Eur J Clin Nutr pmid:11248877
Korotkova M et al. Maternal essential fatty acid deficiency depresses serum leptin levels in suckling rat pups. 2001 J. Lipid Res. pmid:11254747
Moriguchi T et al. Reversal of docosahexaenoic acid deficiency in the rat brain, retina, liver, and serum. 2001 J. Lipid Res. pmid:11254754
Wolff RL et al. Alpha-linolenic acid and its delta5-desaturation product, coniferonic acid, in the seed lipids of Tsuga and Hesperopeuce as a taxonomic means to differentiate the two genera. 2001 Lipids pmid:11269703
Elias SL and Innis SM Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. 2001 Am. J. Clin. Nutr. pmid:11273857
Robertson RM and Smaha L Can a Mediterranean-style diet reduce heart disease? 2001 Circulation pmid:11282917
Kris-Etherton P et al. AHA Science Advisory: Lyon Diet Heart Study. Benefits of a Mediterranean-style, National Cholesterol Education Program/American Heart Association Step I Dietary Pattern on Cardiovascular Disease. 2001 Circulation pmid:11282918
Williard DE et al. Identification of a fatty acid delta6-desaturase deficiency in human skin fibroblasts. 2001 J. Lipid Res. pmid:11290821
Su HM et al. Fetal baboons convert 18:3n-3 to 22:6n-3 in vivo. A stable isotope tracer study. 2001 J. Lipid Res. pmid:11290830
Vermunt SH et al. Dietary trans alpha-linolenic acid from deodorised rapeseed oil and plasma lipids and lipoproteins in healthy men: the TransLinE Study. 2001 Br. J. Nutr. pmid:11299084
Nenseter MS et al. Effect of Norwegian fish powder on risk factors for coronary heart disease among hypercholesterolemic individuals. 2000 Nutr Metab Cardiovasc Dis pmid:11302007
Kaku S et al. Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. 2001 Biosci. Biotechnol. Biochem. pmid:11302164
Kawamoto S et al. Lack of effect of the abnormal fatty acid metabolism in NC/Nga mice on their atopic dermatitis. 2001 Biosci. Biotechnol. Biochem. pmid:11302182
Marmunti M and Catalá A Incorporation of 1-(14)C linoleic acid in rat liver nuclei and chromatin fractions. 2001 Int. J. Biochem. Cell Biol. pmid:11311857
Hrelia S et al. Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11334548
Watkins SM et al. Unique phospholipid metabolism in mouse heart in response to dietary docosahexaenoic or alpha-linolenic acids. 2001 Lipids pmid:11337979
Karlsson S et al. Reactivity of Trametes laccases with fatty and resin acids. 2001 Appl. Microbiol. Biotechnol. pmid:11341313
Murase T et al. Abundant expression of uncoupling protein-2 in the small intestine: up-regulation by dietary fish oil and fibrates. 2001 Biochim. Biophys. Acta pmid:11341955
Trommer H et al. The examination of skin lipid model systems stressed by ultraviolet irradiation in the presence of transition metal ions. 2001 Eur J Pharm Biopharm pmid:11343884