alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

Cross Reference

Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Atherosclerosis D050197 85 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Hyperlipidemias D006949 73 associated lipids
Coronary Disease D003327 70 associated lipids
Colitis D003092 69 associated lipids
Neuroblastoma D009447 66 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Pain D010146 64 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Thrombosis D013927 49 associated lipids
Precancerous Conditions D011230 48 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Arthritis D001168 41 associated lipids
Adenoma D000236 40 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Heart Failure D006333 36 associated lipids
Epilepsy D004827 35 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Stroke D020521 32 associated lipids
Liver Diseases D008107 31 associated lipids
Dermatitis D003872 30 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Breast Neoplasms D001943 24 associated lipids
Cattle Diseases D002418 24 associated lipids
Birth Weight D001724 23 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Hypersensitivity D006967 22 associated lipids
Myocardial Infarction D009203 21 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Tuberculosis D014376 20 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Pregnancy Complications D011248 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Bronchial Spasm D001986 18 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Neoplasms D009369 13 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Deficiency Diseases D003677 12 associated lipids
Cat Diseases D002371 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Aortic Diseases D001018 11 associated lipids
Learning Disorders D007859 11 associated lipids
Overweight D050177 11 associated lipids
Long QT Syndrome D008133 10 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Retinal Degeneration D012162 9 associated lipids
Irritable Bowel Syndrome D043183 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Paraplegia D010264 8 associated lipids
Urinary Bladder Neoplasms D001749 7 associated lipids
Retinitis Pigmentosa D012174 6 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Pancytopenia D010198 6 associated lipids
Endomyocardial Fibrosis D004719 4 associated lipids
Amyloidosis D000686 4 associated lipids
Insect Bites and Stings D007299 4 associated lipids
Mental Fatigue D005222 3 associated lipids
Carcinogenesis D063646 3 associated lipids
Depression, Postpartum D019052 3 associated lipids
Dyskinesias D020820 3 associated lipids
Spinal Cord Ischemia D020760 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Sebaceous Gland Neoplasms D012626 2 associated lipids
Otorhinolaryngologic Neoplasms D010039 2 associated lipids
Conjunctivitis, Allergic D003233 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Per page 10 20 50 100 | Total 2471
Authors Title Published Journal PubMed Link
Sugasini D and Lokesh BR Uptake of α-linolenic acid and its conversion to long chain omega-3 fatty acids in rats fed microemulsions of linseed oil. 2012 Lipids pmid:23104428
Jung DM et al. Chemical properties and oxidative stability of perilla oils obtained from roasted perilla seeds as affected by extraction methods. 2012 J. Food Sci. pmid:23106331
Pereira H et al. Polyunsaturated Fatty acids of marine macroalgae: potential for nutritional and pharmaceutical applications. 2012 Mar Drugs pmid:23118712
Botsoglou E et al. Effect of supplementation of the laying hen diet with olive leaves (Olea europea L.) on lipid oxidation and fatty acid profile of α-linolenic acid enriched eggs during storage. 2012 Br. Poult. Sci. pmid:23130586
Zhao T et al. Impact of roasting on the chemical composition and oxidative stability of perilla oil. 2012 J. Food Sci. pmid:23140339
Msika O et al. NGF blocks polyunsaturated fatty acids biosynthesis in n-3 fatty acid-supplemented PC12 cells. 2012 Biochim. Biophys. Acta pmid:22564256
Moodley R et al. Elemental composition and fatty acid profile of the edible fruits of Amatungula (Carissa macrocarpa) and impact of soil quality on chemical characteristics. 2012 Anal. Chim. Acta pmid:22632042
Lakshmanan V et al. Metabolomic analysis of patient plasma yields evidence of plant-like α-linolenic acid metabolism in Plasmodium falciparum. 2012 J. Infect. Dis. pmid:22566569
Shimpukade B et al. Discovery of a potent and selective GPR120 agonist. 2012 J. Med. Chem. pmid:22519963
Shinohara N et al. Jacaric acid, a linolenic acid isomer with a conjugated triene system, has a strong antitumor effect in vitro and in vivo. 2012 Biochim. Biophys. Acta pmid:22521763
Kim N and Choe E Singlet oxygen-related photooxidative stability and antioxidant changes of diacylglycerol-rich oil derived from mixture of olive and perilla oil. 2012 J. Food Sci. pmid:23057833
Georgiadi A et al. Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. 2012 Physiol. Genomics pmid:22274564
Larsen MK et al. Fatty acid, tocopherol and carotenoid content in herbage and milk affected by sward composition and season of grazing. 2012 J. Sci. Food Agric. pmid:22337263
Angulo J et al. Nutritional evaluation of fruit and vegetable waste as feedstuff for diets of lactating Holstein cows. 2012 J. Environ. Manage. pmid:21784573
Pirat C et al. Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators. 2012 J. Med. Chem. pmid:22260081
Huang T et al. Effect of n-3 polyunsaturated fatty acid on gene expression of the critical enzymes involved in homocysteine metabolism. 2012 Nutr J pmid:22260268
Gaquerel E et al. Nicotiana attenuata α-DIOXYGENASE1 through its production of 2-hydroxylinolenic acid is required for intact plant defense expression against attack from Manduca sexta larvae. 2012 New Phytol. pmid:22937952
Aliani M et al. Effect of flax addition on the flavor profile and acceptability of bagels. 2012 J. Food Sci. pmid:22260132
Lerch S et al. Rapeseed or linseed in grass-based diets: effects on conjugated linoleic and conjugated linolenic acid isomers in milk fat from Holstein cows over 2 consecutive lactations. 2012 J. Dairy Sci. pmid:22999291
Wilk JB et al. Plasma and dietary omega-3 fatty acids, fish intake, and heart failure risk in the Physicians' Health Study. 2012 Am. J. Clin. Nutr. pmid:22952185
Reinders I et al. Association of serum n-3 polyunsaturated fatty acids with C-reactive protein in men. 2012 Eur J Clin Nutr pmid:22113248
Kuhns EH et al. A lepidopteran aminoacylase (L-ACY-1) in Heliothis virescens (Lepidoptera: Noctuidae) gut lumen hydrolyzes fatty acid-amino acid conjugates, elicitors of plant defense. 2012 Insect Biochem. Mol. Biol. pmid:22056272
Mitra K et al. Studies of reaction variables for lipase-catalyzed production of alpha-linolenic acid enriched structured lipid and oxidative stability with antioxidants. 2012 J. Food Sci. pmid:22122200
Couëdelo L et al. The fraction of α-linolenic acid present in the sn-2 position of structured triacylglycerols decreases in lymph chylomicrons and plasma triacylglycerols during the course of lipid absorption in rats. 2012 J. Nutr. pmid:22131546
Nwaru BI et al. Maternal intake of fatty acids during pregnancy and allergies in the offspring. 2012 Br. J. Nutr. pmid:22067943
Pal M and Ghosh M Prophylactic effect of α-linolenic acid and α-eleostearic acid against MeHg induced oxidative stress, DNA damage and structural changes in RBC membrane. 2012 Food Chem. Toxicol. pmid:22683484
Kowalska A et al. Impact of diets with different proportions of linseed and sunflower oils on the growth, liver histology, immunological and chemical blood parameters, and proximate composition of pikeperch Sander lucioperca (L.). 2012 Fish Physiol. Biochem. pmid:21656178
Mirmiran P et al. Association between interaction and ratio of ω-3 and ω-6 polyunsaturated fatty acid and the metabolic syndrome in adults. 2012 Nutrition pmid:22459553
Du Q et al. Dairy fat blends high in α-linolenic acid are superior to n-3 fatty-acid-enriched palm oil blends for increasing DHA levels in the brains of young rats. 2012 J. Nutr. Biochem. pmid:22445803
Miyake Y et al. Dietary meat and fat intake and prevalence of rhinoconjunctivitis in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study. 2012 Nutr J pmid:22449171
Nakamura YK et al. Modulation of oxidative stress by γ-glutamylcysteine (GGC) and conjugated linoleic acid (CLA) isomer mixture in human umbilical vein endothelial cells. 2012 Food Chem. Toxicol. pmid:22490668
Zhang LH et al. [Effects of alpha-linolenic acid on inflammation and oxidative stress in the diabetic rats]. 2012 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:22493899
Fatima T et al. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. 2012 PLoS ONE pmid:22558083
Luo ZM et al. A new norisoprenoid and other compounds from Fuzhuan brick tea. 2012 Molecules pmid:22430120
Ibrahim A et al. Dietary α-linolenic acid-rich formula reduces adhesion molecules in rats with experimental colitis. 2012 Nutrition pmid:22261574
Zhang H et al. A mechanism underlying the effects of polyunsaturated fatty acids on breast cancer. 2012 Int. J. Mol. Med. pmid:22692672
Marei WF et al. Differential effects of linoleic and alpha-linolenic fatty acids on spatial and temporal mitochondrial distribution and activity in bovine oocytes. 2012 Reprod. Fertil. Dev. pmid:22697118
Kronberg SL et al. Treatment of flaxseed to reduce biohydrogenation of α-linolenic acid by ruminal microbes in sheep and cattle, and increase n-3 fatty acid concentrations in red meat. 2012 J. Anim. Sci. pmid:22696616
Passos PP et al. Dopaminergic cell populations of the rat substantia nigra are differentially affected by essential fatty acid dietary restriction over two generations. 2012 J. Chem. Neuroanat. pmid:22687395
Monteiro J et al. Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse. 2012 Lipids Health Dis pmid:22642787
Castro LF et al. Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates. 2012 PLoS ONE pmid:22384110
Huan M et al. In vivo anti-tumor activity of a new doxorubicin conjugate via α-linolenic acid. 2012 Biosci. Biotechnol. Biochem. pmid:22878199
Zhang G et al. [Effects of fatty acids on proliferation and differentiation of myoblast]. 2012 Wei Sheng Yan Jiu pmid:23424861
Santos FS et al. Status of cis and trans fatty acids in Brazilian adolescent mothers and their newborns. 2012 J Pediatr Adolesc Gynecol pmid:22840939
Harland DR et al. Acute effects of prostaglandin E1 and E2 on vascular reactivity and blood flow in situ in the chick chorioallantoic membrane. 2012 Aug-Sep Prostaglandins Leukot. Essent. Fatty Acids pmid:22858445
Hofacer R et al. Omega-3 fatty acid deficiency increases stearoyl-CoA desaturase expression and activity indices in rat liver: positive association with non-fasting plasma triglyceride levels. 2012 Jan-Feb Prostaglandins Leukot. Essent. Fatty Acids pmid:22047910
Tsuzuki W Inconsistencies in a highly polar capillary gas chromatography column and necessity of column performance checks for trans fatty acid measurement. 2012 Nov-Dec J AOAC Int pmid:23451392
Kartikasari LR et al. Dietary alpha-linolenic acid enhances omega-3 long chain polyunsaturated fatty acid levels in chicken tissues. 2012 Oct-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:22925778
Stivala S et al. Dietary α-linolenic acid increases the platelet count in ApoE-/- mice by reducing clearance. 2013 Blood pmid:23801636
Pan X et al. Identification of a pair of phospholipid:diacylglycerol acyltransferases from developing flax (Linum usitatissimum L.) seed catalyzing the selective production of trilinolenin. 2013 J. Biol. Chem. pmid:23824186
Nakashima R et al. Exposure to DEHP decreased four fatty acid levels in plasma of prepartum mice. 2013 Toxicology pmid:23619606
Wang DQ et al. [Alpha-linolenic acid improves insulin sensitivity in obese patients]. 2013 Zhonghua Yi Xue Za Zhi pmid:23648351
Oh HJ et al. Production of 10-hydroxy-12,15(Z,Z)-octadecadienoic acid from α-linolenic acid by permeabilized cells of recombinant Escherichia coli expressing the oleate hydratase gene of Stenotrophomonas maltophilia. 2013 Biotechnol. Lett. pmid:23690042
Schuchardt JP et al. Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23694766
Sengupta A and Ghosh M Protective effect of eicosapentaenoic acid-docosahexaenoic acid and alpha-linolenic acid rich phytosterol ester on brain antioxidant status and brain lipid composition in hypercholesterolemic rats. 2013 Indian J. Exp. Biol. pmid:23678545
Rao CV et al. Prevention of familial adenomatous polyp development in APC min mice and azoxymethane-induced colon carcinogenesis in F344 Rats by ω-3 fatty acid rich perilla oil. 2013 Nutr Cancer pmid:23682783
Hutchins AM et al. Daily flaxseed consumption improves glycemic control in obese men and women with pre-diabetes: a randomized study. 2013 Nutr Res pmid:23684438
Simon MC et al. Fatty acids modulate cytokine and chemokine secretion of stimulated human whole blood cultures in diabetes. 2013 Clin. Exp. Immunol. pmid:23600826
Foster M et al. Inflammation markers predict zinc transporter gene expression in women with type 2 diabetes mellitus. 2013 J. Nutr. Biochem. pmid:23643522
Mapiye C et al. Effects of feeding flaxseed or sunflower-seed in high-forage diets on beef production, quality and fatty acid composition. 2013 Meat Sci. pmid:23669875
Emery JA et al. Δ-6 Desaturase substrate competition: dietary linoleic acid (18:2n-6) has only trivial effects on α-linolenic acid (18:3n-3) bioconversion in the teleost rainbow trout. 2013 PLoS ONE pmid:23460861
Stamey Lanier J et al. Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. 2013 Lipids pmid:23504269
Saubeau G et al. Differential induction of oxylipin pathway in potato and tobacco cells by bacterial and oomycete elicitors. 2013 Plant Cell Rep. pmid:23479199
Cao AH et al. Composition of long chain polyunsaturated fatty acids (LC-PUFAs) in different encephalic regions and its association with behavior in spontaneous hypertensive rat (SHR). 2013 Brain Res. pmid:23811335
Moloney AP et al. Colour of fat, and colour, fatty acid composition and sensory characteristics of muscle from heifers offered alternative forages to grass silage in a finishing ration. 2013 Meat Sci. pmid:23806853
Lagarde M et al. Lipidomics of essential fatty acids and oxygenated metabolites. 2013 Mol Nutr Food Res pmid:23818385
Gregory MK et al. Functional characterization of the chicken fatty acid elongases. 2013 J. Nutr. pmid:23173174
Tu WC et al. Dietary alpha-linolenic acid does not enhance accumulation of omega-3 long-chain polyunsaturated fatty acids in barramundi (Lates calcarifer). 2013 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:23085323
Van Ba H et al. Significant influence of particular unsaturated fatty acids and pH on the volatile compounds in meat-like model systems. 2013 Meat Sci. pmid:23632107
Poudyal H et al. Effects of ALA, EPA and DHA in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats. 2013 J. Nutr. Biochem. pmid:23026492
Yang YX et al. Effects of duodenal infusion of free α-linolenic acid on the plasma and milk proteome of lactating dairy cows. 2013 Animal pmid:23031206
Blanchard H et al. Comparative effects of well-balanced diets enriched in α-linolenic or linoleic acids on LC-PUFA metabolism in rat tissues. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23579035
Hawkins A et al. Effects of urea formaldehyde condensation polymer treatment of flaxseed on ruminal digestion and lactation in dairy cows. 2013 J. Dairy Sci. pmid:23548281
Botelho PB et al. Effect of Echium oil compared with marine oils on lipid profile and inhibition of hepatic steatosis in LDLr knockout mice. 2013 Lipids Health Dis pmid:23510369
MacIntosh BA et al. Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research. 2013 Br. J. Nutr. pmid:23328113
Ma T et al. Effect of droplet size on autoxidation rates of methyl linoleate and α-linolenate in an oil-in-water emulsion. 2013 J Oleo Sci pmid:24292352
Lau BY et al. Investigating the role of polyunsaturated fatty acids in bone development using animal models. 2013 Molecules pmid:24248147
Sonne DP and Knop FK Cardiovascular effects of alpha-linolenic acid--a possible role of glucagon-like peptide-1. 2013 Exp. Biol. Med. (Maywood) pmid:24174423
Hoque M et al. Oleic acid may be the key contributor in the BAMLET-induced erythrocyte hemolysis and tumoricidal action. 2013 PLoS ONE pmid:24039698
Moallem U et al. Dietary α-linolenic acid from flaxseed oil improved folliculogenesis and IVF performance in dairy cows, similar to eicosapentaenoic and docosahexaenoic acids from fish oil. 2013 Reproduction pmid:24062566
Arya E et al. Effect of Perilla frutescens fixed oil on experimental esophagitis in albino Wistar rats. 2013 Biomed Res Int pmid:24027769
Carotenuto F et al. A diet supplemented with ALA-rich flaxseed prevents cardiomyocyte apoptosis by regulating caveolin-3 expression. 2013 Cardiovasc. Res. pmid:24042018
Zhang W et al. Alpha-linolenic acid exerts an endothelial protective effect against high glucose injury via PI3K/Akt pathway. 2013 PLoS ONE pmid:23861910
Randall KM et al. Effects of dietary supplementation of coriander oil, in canola oil diets, on the metabolism of [1-(14)C] 18:3n-3 and [1-(14)C] 18:2n-6 in rainbow trout hepatocytes. 2013 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:23867781
Oliva ME et al. Dietary Salba (Salvia hispanica L) seed rich in α-linolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24120122
Dai J et al. Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro. 2013 Lipids Health Dis pmid:23663688
Ogata F et al. Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). 2013 J Oleo Sci pmid:23391535
Arm JP et al. Impact of botanical oils on polyunsaturated fatty acid metabolism and leukotriene generation in mild asthmatics. 2013 Lipids Health Dis pmid:24088297
Zhang W et al. Alpha-linolenic acid intake prevents endothelial dysfunction in high-fat diet-fed streptozotocin rats and underlying mechanisms. 2013 VASA pmid:24220118
Rodriguez-Leyva D et al. Potent antihypertensive action of dietary flaxseed in hypertensive patients. 2013 Hypertension pmid:24126178
Hoffmann I and Oliw EH Discovery of a linoleate 9S-dioxygenase and an allene oxide synthase in a fusion protein of Fusarium oxysporum. 2013 J. Lipid Res. pmid:24082064
Al-Bishri WM Favorable effects of flaxseed supplemented diet on liver and kidney functions in hypertensive Wistar rats. 2013 J Oleo Sci pmid:24005015
Yang D et al. Antioxidative activities of Ginkgo biloba extract on oil/water emulsion system prepared from an enzymatically modified lipid containing alpha-linolenic acid. 2013 J. Food Sci. pmid:23278764
Caligiuri SP et al. Dietary linoleic acid and α-linolenic acid differentially affect renal oxylipins and phospholipid fatty acids in diet-induced obese rats. 2013 J. Nutr. pmid:23902961
Shibata E et al. Free fatty acids inhibit protein tyrosine phosphatase 1B and activate Akt. 2013 Cell. Physiol. Biochem. pmid:24107614
Reinders I et al. Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study. 2013 Eur J Clin Nutr pmid:24084512
Smink W et al. Effect of intake of linoleic acid and α-linolenic acid levels on conversion into long-chain polyunsaturated fatty acids in backfat and in intramuscular fat of growing pigs. 2013 J Anim Physiol Anim Nutr (Berl) pmid:22463497
Gibson RA et al. Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22515943
Benbrook CM et al. Organic production enhances milk nutritional quality by shifting fatty acid composition: a United States-wide, 18-month study. 2013 PLoS ONE pmid:24349282
de Oliveira Otto MC et al. Circulating and dietary omega-3 and omega-6 polyunsaturated fatty acids and incidence of CVD in the Multi-Ethnic Study of Atherosclerosis. 2013 J Am Heart Assoc pmid:24351702