Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Guesnet P et al. | Dietary alpha-linolenic acid deficiency in the rat. I. Effects on reproduction and postnatal growth. | 1986 | Reprod Nutr Dev | pmid:2877477 |
Guesnet P et al. | Effects of dietary alpha-linolenic acid deficiency during pregnancy and lactation on lipid fatty acid composition of liver and serum in the rat. | 1988 | Reprod Nutr Dev | pmid:2897705 |
Kiernan M et al. | The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. | 2013 | Reprod. Fertil. Dev. | pmid:23036717 |
Marei WF et al. | Differential effects of linoleic and alpha-linolenic fatty acids on spatial and temporal mitochondrial distribution and activity in bovine oocytes. | 2012 | Reprod. Fertil. Dev. | pmid:22697118 |
Acar N et al. | The retina is more susceptible than the brain and the liver to the incorporation of trans isomers of DHA in rats consuming trans isomers of alpha-linolenic acid. | 2006 Sep-Oct | Reprod. Nutr. Dev. | pmid:17107641 |
Bretillon L et al. | In vivo oxidation of [9-14C] cyclic fatty acids derived from linolenic acid in the rat. | 2006 Mar-Apr | Reprod. Nutr. Dev. | pmid:16597424 |
Burdge GC and Calder PC | Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. | 2005 Sep-Oct | Reprod. Nutr. Dev. | pmid:16188209 |
De Lorgeril M and Salen P | Use and misuse of dietary fatty acids for the prevention and treatment of coronary heart disease. | 2004 May-Jun | Reprod. Nutr. Dev. | pmid:15460167 |
Morise A et al. | Dose effect of alpha-linolenic acid on lipid metabolism in the hamster. | 2005 Jul-Aug | Reprod. Nutr. Dev. | pmid:16045889 |
Ponter AA et al. | Effect of a supplement rich in linolenic acid added to the diet of post partum dairy cows on ovarian follicle growth, and milk and plasma fatty acid compositions. | 2006 Jan-Feb | Reprod. Nutr. Dev. | pmid:16438912 |