Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pähkla R et al. | Comparison of the antioxidant activity of melatonin and pinoline in vitro. | 1998 | J. Pineal Res. | pmid:9510434 |
Bretillon L et al. | Oxidative metabolism of [1-14C] mono-trans isomers of linoleic and alpha-linolenic acids in the rat. | 1998 | Biochim. Biophys. Acta | pmid:9507133 |
Zimmer L et al. | Chronic n-3 polyunsaturated fatty acid diet-deficiency acts on dopamine metabolism in the rat frontal cortex: a microdialysis study. | 1998 | Neurosci. Lett. | pmid:9502233 |
Yehuda S et al. | Fatty acids and brain peptides. | 1998 | Peptides | pmid:9493877 |
Ramesh G and Das UN | Effect of cis-unsaturated fatty acids on Meth-A ascitic tumour cells in vitro and in vivo. | 1998 | Cancer Lett. | pmid:9489490 |
Schimke I et al. | Influence of long-term supplementation with alpha-linolenic acid on myocardial lipid peroxidation and antioxidative capacity in spontaneously hypertensive rats. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9431820 |
Lu Z et al. | Low linolenate and commercial soybean oils diminish serum HDL cholesterol in young free-living adult females. | 1997 | J Am Coll Nutr | pmid:9430084 |
van Niel MH and Beynen AC | The intake of polyunsaturated fatty acids by cats is reflected in their adipose tissue. | 1997 | Vet Q | pmid:9413110 |
Sakamoto T et al. | Alteration of low-temperature susceptibility of the cyanobacterium Synechococcus sp. PCC 7002 by genetic manipulation of membrane lipid unsaturation. | 1998 | Arch. Microbiol. | pmid:9396831 |
Greiner RC et al. | Brain docosahexaenoate accretion in fetal baboons: bioequivalence of dietary alpha-linolenic and docosahexaenoic acids. | 1997 | Pediatr. Res. | pmid:9396565 |
Anthony FA et al. | Psoralen-fatty acid adducts activate melanocyte protein kinase C: a proposed mechanism for melanogenesis induced by 8-methoxypsoralen and ultraviolet A light. | 1997 Feb-Apr | Photodermatol Photoimmunol Photomed | pmid:9361122 |
Kim KS et al. | Dietary alpha-linolenic acid increases the biosynthesis of the choline glycerophospholipids from [14C]CDPcholine in rat liver and kidney but not in brain. | 1997 | Neurochem. Res. | pmid:9342734 |
Ratnayake WM et al. | Essential fatty acids and their trans geometrical isomers in powdered and liquid infant formulas sold in Canada. | 1997 | J. Pediatr. Gastroenterol. Nutr. | pmid:9327370 |
Specht-Overholt S et al. | Fatty acid composition of commercially manufactured omega-3 enriched pork products, haddock, and mackerel. | 1997 | J. Anim. Sci. | pmid:9303450 |
Shi X et al. | Efficacy of taurine based compounds as hydroxyl radical scavengers in silica induced peroxidation. | 1997 Sep-Oct | Ann. Clin. Lab. Sci. | pmid:9303176 |
Hall JA et al. | Lipid composition of hepatic and adipose tissues from normal cats and from cats with idiopathic hepatic lipidosis. | 1997 Jul-Aug | J. Vet. Intern. Med. | pmid:9298479 |
Jensen CL et al. | Effect of dietary linoleic/alpha-linolenic acid ratio on growth and visual function of term infants. | 1997 | J. Pediatr. | pmid:9290604 |
Carlson SE | Functional effects of increasing omega-3 fatty acid intake. | 1997 | J. Pediatr. | pmid:9290597 |
Freese R and Mutanen M | Alpha-linolenic acid and marine long-chain n-3 fatty acids differ only slightly in their effects on hemostatic factors in healthy subjects. | 1997 | Am. J. Clin. Nutr. | pmid:9280178 |