Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jeppesen PB et al. | Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. | 1999 | Am. J. Clin. Nutr. | pmid:10393142 |
Murakami K et al. | Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403814 |
Schultz JR and Clarke CF | Characterization of Saccharomyces cerevisiae ubiquinone-deficient mutants. | 1999 | Biofactors | pmid:10416023 |
Delton-Vandenbroucke I et al. | A role for cerebral and retinal endothelial cells in the supply of docosahexaenoic acid to the brain and the retina? | 1999 | Lipids | pmid:10419115 |
Vermunt SH et al. | Effects of age and dietary n-3 fatty acids on the metabolism of [13C]-alpha-linolenic acid. | 1999 | Lipids | pmid:10419119 |
Turpeinen AM et al. | A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans. | 1999 | Lipids | pmid:10419181 |
Su HM et al. | Dietary 18:3n-3 and 22:6n-3 as sources of 22:6n-3 accretion in neonatal baboon brain and associated organs. | 1999 | Lipids | pmid:10419199 |
Wenger FA et al. | Does dietary alpha-linolenic acid promote liver metastases in pancreatic carcinoma initiated by BOP in Syrian hamster? | 1999 | Ann. Nutr. Metab. | pmid:10436311 |
Khozin-Goldberg I et al. | Salicylhydroxamic acid inhibits delta6 desaturation in the microalga Porphyridium cruentum. | 1999 | Biochim. Biophys. Acta | pmid:10446425 |
Becker CC et al. | Effects of butter oil blends with increased concentrations of stearic, oleic and linolenic acid on blood lipids in young adults. | 1999 | Eur J Clin Nutr | pmid:10452408 |
Warnotte C et al. | Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. | 1999 | Mol. Cell. Endocrinol. | pmid:10459862 |
Tou JC and Thompson LU | Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures. | 1999 | Carcinogenesis | pmid:10469631 |
Sato A et al. | Long-term n-3 fatty acid deficiency induces no substantial change in the rate of protein synthesis in rat brain and liver. | 1999 | Biol. Pharm. Bull. | pmid:10480312 |
Kankaanpää P et al. | Dietary fatty acids and allergy. | 1999 | Ann. Med. | pmid:10480759 |
Koch T et al. | Differential induction of plant volatile biosynthesis in the lima bean by early and late intermediates of the octadecanoid-signaling pathway. | 1999 | Plant Physiol. | pmid:10482670 |
Emken EA et al. | Effect of dietary docosahexaenoic acid on desaturation and uptake in vivo of isotope-labeled oleic, linoleic, and linolenic acids by male subjects. | 1999 | Lipids | pmid:10529088 |
Angerosa F et al. | Virgin olive oil volatile compounds from lipoxygenase pathway and characterization of some italian cultivars. | 1999 | J. Agric. Food Chem. | pmid:10552376 |
Lin MY and Yen CL | Inhibition of lipid peroxidation by Lactobacillus acidophilus and Bifidobacterium longum. | 1999 | J. Agric. Food Chem. | pmid:10552700 |
Elmore JS et al. | Effect of the polyunsaturated fatty acid composition of beef muscle on the profile of aroma volatiles. | 1999 | J. Agric. Food Chem. | pmid:10564028 |
Hanley K et al. | Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators. | 1999 | J. Invest. Dermatol. | pmid:10571735 |