| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Amyloidosis | D000686 | 4 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Urinary Bladder Neoplasms | D001749 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Cat Diseases | D002371 | 12 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Conjunctivitis, Allergic | D003233 | 1 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vrinten P et al. | Two FAD3 desaturase genes control the level of linolenic acid in flax seed. | 2005 | Plant Physiol. | pmid:16113219 |
| Thiébaut AC et al. | [Unsaturated fatty acids intake and breast cancer risk: epidemiological data review]. | 2005 | Bull Cancer | pmid:16123005 |
| Astorg P | [Dietary fatty acids and colorectal and prostate cancers: epidemiological studies]. | 2005 | Bull Cancer | pmid:16123006 |
| Bougnoux P and Menanteau J | [Dietary fatty acids and experimental carcinogenesis]. | 2005 | Bull Cancer | pmid:16123007 |
| Taha AY et al. | Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats. | 2005 | Metab. Clin. Exp. | pmid:16125522 |
| Wang YL et al. | LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui. | 2005 | Anal Bioanal Chem | pmid:16132135 |
| Bavelaar FJ et al. | Plasma lipids and fatty acid composition in parrots in relation to the intake of alpha-linolenic acid from two feed mixtures. | 2005 | J Anim Physiol Anim Nutr (Berl) | pmid:16138866 |
| Cheng Z et al. | The effect of supplementation with n-6 polyunsaturated fatty acids on 1-, 2- and 3-series prostaglandin F production by ovine uterine epithelial cells. | 2005 | Biochim. Biophys. Acta | pmid:16140575 |
| Rose HJ et al. | Fat intakes of children with PKU on low phenylalanine diets. | 2005 | J Hum Nutr Diet | pmid:16150136 |
| Merchant AT et al. | Intake of n-6 and n-3 fatty acids and fish and risk of community-acquired pneumonia in US men. | 2005 | Am. J. Clin. Nutr. | pmid:16155282 |
| Addis M et al. | Milk and cheese fatty acid composition in sheep fed Mediterranean forages with reference to conjugated linoleic acid cis-9,trans-11. | 2005 | J. Dairy Sci. | pmid:16162517 |
| Zhao G et al. | Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cells. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16169525 |
| Singh S et al. | Antibacterial activity of Ocimum sanctum L. fixed oil. | 2005 | Indian J. Exp. Biol. | pmid:16187537 |
| Burdge GC and Calder PC | Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. | 2005 Sep-Oct | Reprod. Nutr. Dev. | pmid:16188209 |
| Llanos A et al. | Infants with intrauterine growth restriction have impaired formation of docosahexaenoic acid in early neonatal life: a stable isotope study. | 2005 | Pediatr. Res. | pmid:16189202 |
| Ermidou-Pollet S et al. | Influence of subcutaneous injection of essential fatty acids on the stress-induced modifications of rat platelet aggregation and membrane lipid composition. | 2005 | Acta. Biol. Hung. | pmid:16196200 |
| Oikarinen SI et al. | Effects of a flaxseed mixture and plant oils rich in alpha-linolenic acid on the adenoma formation in multiple intestinal neoplasia (Min) mice. | 2005 | Br. J. Nutr. | pmid:16197574 |
| Xiao Y et al. | Distribution, depletion and recovery of docosahexaenoic acid are region-specific in rat brain. | 2005 | Br. J. Nutr. | pmid:16197579 |
| Flachs P et al. | Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce beta-oxidation in white fat. | 2005 | Diabetologia | pmid:16205884 |
| Cohen SL and Ward WE | Flaxseed oil and bone development in growing male and female mice. | 2005 | J. Toxicol. Environ. Health Part A | pmid:16207634 |
| Christensen JH et al. | Alpha-linolenic acid and heart rate variability in women examined for coronary artery disease. | 2005 | Nutr Metab Cardiovasc Dis | pmid:16216720 |
| Ribeiro CV et al. | Biohydrogenation of fatty acids and digestibility of fresh alfalfa or alfalfa hay plus sucrose in continuous culture. | 2005 | J. Dairy Sci. | pmid:16230707 |
| Colombo C et al. | Plant-based diet, serum fatty acid profile, and free radicals in postmenopausal women: the diet and androgens (DIANA) randomized trial. | 2005 Jul-Sep | Int. J. Biol. Markers | pmid:16240844 |
| Grechkin AN et al. | Thermal conversions of trimethylsilyl peroxides of linoleic and linolenic acids. | 2005 | Chem. Phys. Lipids | pmid:16242681 |
| Schuh C and Schieberle P | Characterization of (E,E,Z)-2,4,6-nonatrienal as a character impact aroma compound of oat flakes. | 2005 | J. Agric. Food Chem. | pmid:16248574 |
| Bajaj M et al. | Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients. | 2005 | Diabetes | pmid:16249438 |
| Kabagambe EK et al. | The type of oil used for cooking is associated with the risk of nonfatal acute myocardial infarction in costa rica. | 2005 | J. Nutr. | pmid:16251629 |
| Cunningham E | Does the n-3 fatty acid alpha-linolenic acid have an impact on coronary heart disease? | 2005 | J Am Diet Assoc | pmid:16256769 |
| Ganga R et al. | Effect of dietary lipids on plasma fatty acid profiles and prostaglandin and leptin production in gilthead seabream (Sparus aurata). | 2005 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:16257554 |
| Anderson GJ et al. | Can prenatal N-3 fatty acid deficiency be completely reversed after birth? Effects on retinal and brain biochemistry and visual function in rhesus monkeys. | 2005 | Pediatr. Res. | pmid:16257925 |
| Lengqvist J et al. | Specificity of receptor-ligand interactions and their effect on dimerisation as observed by electrospray mass spectrometry: bile acids form stable adducts to the RXRalpha. | 2005 | J Mass Spectrom | pmid:16258897 |
| Munsterman AS et al. | Effects of the omega-3 fatty acid, alpha-linolenic acid, on lipopolysaccharide-challenged synovial explants from horses. | 2005 | Am. J. Vet. Res. | pmid:16261822 |
| Okuyama H | [Need to change the direction of cholesterol-related medication--a problem of great urgency]. | 2005 | Yakugaku Zasshi | pmid:16272805 |
| Ulkowski M et al. | Use of differential scanning calorimetry to study lipid oxidation. 1. Oxidative stability of lecithin and linolenic acid. | 2005 | J. Agric. Food Chem. | pmid:16277404 |
| Sabaté J et al. | Does regular walnut consumption lead to weight gain? | 2005 | Br. J. Nutr. | pmid:16277792 |
| Friesen R and Innis SM | Maternal dietary fat alters amniotic fluid and fetal intestinal membrane essential n-6 and n-3 fatty acids in the rat. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16282365 |
| Heurteaux C et al. | Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia. | 2006 | Neuroscience | pmid:16289892 |
| Boken SL et al. | Effect of grazing and fat supplementation on production and reproduction of Holstein cows. | 2005 | J. Dairy Sci. | pmid:16291617 |
| Barceló-Coblijn G et al. | Dietary alpha-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels. | 2005 | Lipids | pmid:16296397 |
| Lehner F et al. | Metabolic effects of intravenous LCT or MCT/LCT lipid emulsions in preterm infants. | 2006 | J. Lipid Res. | pmid:16299352 |
| Albert CM et al. | Dietary alpha-linolenic acid intake and risk of sudden cardiac death and coronary heart disease. | 2005 | Circulation | pmid:16301356 |
| Nielsen AA et al. | Omega-3 fatty acids inhibit an increase of proinflammatory cytokines in patients with active Crohn's disease compared with omega-6 fatty acids. | 2005 | Aliment. Pharmacol. Ther. | pmid:16305726 |
| Alamsjah MA et al. | Isolation and structure determination of algicidal compounds from Ulva fasciata. | 2005 | Biosci. Biotechnol. Biochem. | pmid:16306701 |
| Joshi K et al. | Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD). | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16314082 |
| Goyens PL and Mensink RP | The dietary alpha-linolenic acid to linoleic acid ratio does not affect the serum lipoprotein profile in humans. | 2005 | J. Nutr. | pmid:16317123 |
| Thijssen MA et al. | Stearic, oleic, and linoleic acids have comparable effects on markers of thrombotic tendency in healthy human subjects. | 2005 | J. Nutr. | pmid:16317124 |
| Patch CS et al. | The use of novel foods enriched with long-chain n-3 fatty acids to increase dietary intake: a comparison of methodologies assessing nutrient intake. | 2005 | J Am Diet Assoc | pmid:16321598 |
| Cunnane SC et al. | Suckling rats actively recycle carbon from alpha-linolenate into newly synthesized lipids even during extreme dietary deficiency of n-3 polyunsaturates. | 2006 | Pediatr. Res. | pmid:16326997 |
| Rodriguez-Cruz M et al. | Synthesis of long-chain polyunsaturated fatty acids in lactating mammary gland: role of Delta5 and Delta6 desaturases, SREBP-1, PPARalpha, and PGC-1. | 2006 | J. Lipid Res. | pmid:16333142 |
| Hosmer C | Ask the doctor. Are the omega-3 fats in flaxseed oil as good for the heart as those in fish or fish oil? Do they have the same side effects? The American Heart Association warns about getting more than 3 grams of omega-3 fats a day without a doctor's supervision, but one teaspoon of my concentrated flaxseed oil--the recommended dose--contains 6.2 grams. Should I be worried? | 2005 | Harv Heart Lett | pmid:16363041 |