| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Amyloidosis | D000686 | 4 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Urinary Bladder Neoplasms | D001749 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Cat Diseases | D002371 | 12 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Conjunctivitis, Allergic | D003233 | 1 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Greiner RC et al. | Brain docosahexaenoate accretion in fetal baboons: bioequivalence of dietary alpha-linolenic and docosahexaenoic acids. | 1997 | Pediatr. Res. | pmid:9396565 |
| Anthony FA et al. | Psoralen-fatty acid adducts activate melanocyte protein kinase C: a proposed mechanism for melanogenesis induced by 8-methoxypsoralen and ultraviolet A light. | 1997 Feb-Apr | Photodermatol Photoimmunol Photomed | pmid:9361122 |
| Kim KS et al. | Dietary alpha-linolenic acid increases the biosynthesis of the choline glycerophospholipids from [14C]CDPcholine in rat liver and kidney but not in brain. | 1997 | Neurochem. Res. | pmid:9342734 |
| Ratnayake WM et al. | Essential fatty acids and their trans geometrical isomers in powdered and liquid infant formulas sold in Canada. | 1997 | J. Pediatr. Gastroenterol. Nutr. | pmid:9327370 |
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| Shi X et al. | Efficacy of taurine based compounds as hydroxyl radical scavengers in silica induced peroxidation. | 1997 Sep-Oct | Ann. Clin. Lab. Sci. | pmid:9303176 |
| Hall JA et al. | Lipid composition of hepatic and adipose tissues from normal cats and from cats with idiopathic hepatic lipidosis. | 1997 Jul-Aug | J. Vet. Intern. Med. | pmid:9298479 |
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| Carlson SE | Functional effects of increasing omega-3 fatty acid intake. | 1997 | J. Pediatr. | pmid:9290597 |
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| Okuno M et al. | Perilla oil prevents the excessive growth of visceral adipose tissue in rats by down-regulating adipocyte differentiation. | 1997 | J. Nutr. | pmid:9278555 |
| Tomioka H et al. | Effector molecules of the host defence mechanism against Mycobacterium avium complex: the evidence showing that reactive oxygen intermediates, reactive nitrogen intermediates, and free fatty acids each alone are not decisive in expression of macrophage antimicrobial activity against the parasites. | 1997 | Clin. Exp. Immunol. | pmid:9276519 |
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| Poon WW et al. | Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants. | 1997 | Mol. Aspects Med. | pmid:9266513 |
| Gatchalian-Yee M et al. | Soybean protein lowers serum cholesterol levels in hamsters: effect of debittered undigested fraction. | 1997 Jul-Aug | Nutrition | pmid:9263255 |
| Huang MZ et al. | Unusual effects of some vegetable oils on the survival time of stroke-prone spontaneously hypertensive rats. | 1997 | Lipids | pmid:9252963 |
| Howlett NG and Avery SV | Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation. | 1997 | Appl. Environ. Microbiol. | pmid:9251184 |
| Parmentier HK et al. | Dietary unsaturated fatty acids affect antibody responses and growth of chickens divergently selected for humoral responses to sheep red blood cells. | 1997 | Poult. Sci. | pmid:9251147 |
| Lorenzini A et al. | Age-related changes in essential fatty acid metabolism in cultured rat heart myocytes. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9250697 |
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| Kelso KA et al. | Effects of dietary supplementation with alpha-linolenic acid on the phospholipid fatty acid composition and quality of spermatozoa in cockerel from 24 to 72 weeks of age. | 1997 | J. Reprod. Fertil. | pmid:9227357 |
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| Kokura S et al. | Efficacy of hyperthermia and polyunsaturated fatty acids on experimental carcinoma. | 1997 | Cancer Res. | pmid:9187121 |
| Harvei S et al. | Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer. | 1997 | Int. J. Cancer | pmid:9178806 |
| Jeffery NM et al. | Effects of variations in the proportions of saturated, monounsaturated and polyunsaturated fatty acids in the rat diet on spleen lymphocyte functions. | 1997 | Br. J. Nutr. | pmid:9175999 |
| Spitzer V et al. | Structure analysis of an allene-containing estolide tetraester triglyceride in the seed oil of Sebastiana commersoniana (Euphorbiaceae). | 1997 | Lipids | pmid:9168462 |
| Guesnet P et al. | Modifying the n-3 fatty acid content of the maternal diet to determine the requirements of the fetal and suckling rat. | 1997 | Lipids | pmid:9168459 |
| Hardwick SJ et al. | Toxicity of polyunsaturated fatty acid esters for human monocyte-macrophages: the anomalous behaviour of cholesteryl linolenate. | 1997 | Free Radic. Res. | pmid:9167940 |
| Smith GM and Isopenko A | Effect of doses of protected polyunsaturated fatty acids on indicators of selenium status of sheep. | 1997 Jan-Feb | Res. Vet. Sci. | pmid:9160431 |
| Sugihara N et al. | Cytotoxicity of food preservatives in cultured rat hepatocytes loaded with linolenic acid. | 1997 | Toxicology | pmid:9160106 |
| Koga T et al. | Linoleic and alpha-linolenic acids differently modify the effects of elaidic acid on polyunsaturated fatty acid metabolism and some immune indices in rats. | 1997 | Br. J. Nutr. | pmid:9155511 |
| Sravan Kumar G and Das UN | Cytotoxic action of alpha-linolenic and eicosapentaenoic acids on myeloma cells in vitro. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9150374 |
| Wagner W and Nootbaar-Wagner U | Prophylactic treatment of migraine with gamma-linolenic and alpha-linolenic acids. | 1997 | Cephalalgia | pmid:9137851 |
| Harris WS | n-3 fatty acids and serum lipoproteins: human studies. | 1997 | Am. J. Clin. Nutr. | pmid:9129504 |
| Vinggaard AM et al. | Arf and RhoA regulate both the cytosolic and the membrane-bound phospholipase D from human placenta. | 1997 | Cell. Signal. | pmid:9113419 |
| Tranchant T et al. | Mechanisms and kinetics of alpha-linolenic acid uptake in Caco-2 clone TC7. | 1997 | Biochim. Biophys. Acta | pmid:9106494 |
| Nishizaki T et al. | Short-term depression and long-term enhancement of ACh-gated channel currents induced by linoleic and linolenic acid. | 1997 | Brain Res. | pmid:9099812 |
| Oh-hashi K et al. | Reevaluation of the effect of a high alpha-linolenate and a high linoleate diet on antigen-induced antibody and anaphylactic responses in mice. | 1997 | Biol. Pharm. Bull. | pmid:9084876 |
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| Yoshida S et al. | Synaptic vesicle ultrastructural changes in the rat hippocampus induced by a combination of alpha-linolenate deficiency and a learning task. | 1997 | J. Neurochem. | pmid:9048773 |
| Babu US et al. | Impact of in vitro fatty acid uptake on nitric oxide production and antilisterial activity of WEHI-3 cells. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8993386 |
| Voskuil DW et al. | Intake and sources of alpha-linolenic acid in Dutch elderly men. | 1996 | Eur J Clin Nutr | pmid:8968698 |
| Applegate TJ and Sell JL | Effect of dietary linoleic to linolenic acid ratio and vitamin E supplementation on vitamin E status of poults. | 1996 | Poult. Sci. | pmid:8966177 |
| Kabir Y and Ide T | Activity of hepatic fatty acid oxidation enzymes in rats fed alpha-linolenic acid. | 1996 | Biochim. Biophys. Acta | pmid:8954134 |
| Howe GA et al. | An octadecanoid pathway mutant (JL5) of tomato is compromised in signaling for defense against insect attack. | 1996 | Plant Cell | pmid:8953771 |
| Awad AB et al. | The effect of unsaturated fatty acids on membrane composition and signal transduction in HT-29 human colon cancer cells. | 1996 | Cancer Lett. | pmid:8950205 |
| Kankofer M et al. | The analysis of fatty acid content and phospholipase A2 activity in placenta of cows with and without retained fetal membranes. | 1996 | Zentralbl Veterinarmed A | pmid:8940891 |