| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Amyloidosis | D000686 | 4 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Urinary Bladder Neoplasms | D001749 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Cat Diseases | D002371 | 12 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Conjunctivitis, Allergic | D003233 | 1 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lenka SK et al. | Comparative analysis of drought-responsive transcriptome in Indica rice genotypes with contrasting drought tolerance. | 2011 | Plant Biotechnol. J. | pmid:20809928 |
| Maeda H et al. | Tocopherols modulate extraplastidic polyunsaturated fatty acid metabolism in Arabidopsis at low temperature. | 2008 | Plant Cell | pmid:18314499 |
| Truitt CL et al. | A plasma membrane protein from Zea mays binds with the herbivore elicitor volicitin. | 2004 | Plant Cell | pmid:14729912 |
| Kunz HH et al. | The ABC transporter PXA1 and peroxisomal beta-oxidation are vital for metabolism in mature leaves of Arabidopsis during extended darkness. | 2009 | Plant Cell | pmid:19794119 |
| Okuley J et al. | Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis. | 1994 | Plant Cell | pmid:7907506 |
| Howe GA et al. | An octadecanoid pathway mutant (JL5) of tomato is compromised in signaling for defense against insect attack. | 1996 | Plant Cell | pmid:8953771 |
| Sánchez-Hernández C et al. | Reduced levels of volatile emissions in jasmonate-deficient spr2 tomato mutants favour oviposition by insect herbivores. | 2006 | Plant Cell Environ. | pmid:17080606 |
| Yara A et al. | Disease resistance against Magnaporthe grisea is enhanced in transgenic rice with suppression of omega-3 fatty acid desaturases. | 2007 | Plant Cell Physiol. | pmid:17716996 |
| Suzuki M et al. | Endogenous alpha-ketol linolenic acid levels in short day-induced cotyledons are closely related to flower induction in Pharbitis nil. | 2003 | Plant Cell Physiol. | pmid:12552145 |
| Yamaguchi S et al. | Identification of a component that induces flowering of Lemna among the reaction products of alpha-ketol linolenic acid (FIF) and norepinephrine. | 2001 | Plant Cell Physiol. | pmid:11726704 |
| Yokoyama M et al. | Stress-induced factor involved in flower formation of Lemna is an alpha-ketol derivative of linolenic acid. | 2000 | Plant Cell Physiol. | pmid:10750715 |
| Küpper FC et al. | Free Fatty Acids and Methyl Jasmonate Trigger Defense Reactions in Laminaria digitata. | 2009 | Plant Cell Physiol. | pmid:19213737 |
| Choi SB et al. | Transcriptional expression characteristics and subcellular localization of ADP-glucose pyrophosphorylase in the oil plant Perilla frutescens. | 2001 | Plant Cell Physiol. | pmid:11230568 |
| Saubeau G et al. | Differential induction of oxylipin pathway in potato and tobacco cells by bacterial and oomycete elicitors. | 2013 | Plant Cell Rep. | pmid:23479199 |
| Freiberger CE et al. | Nutrient content of the edible leaves of seven wild plants from Niger. | 1998 | Plant Foods Hum Nutr | pmid:10890758 |
| Jin F et al. | Supplementation of milled chia seeds increases plasma ALA and EPA in postmenopausal women. | 2012 | Plant Foods Hum Nutr | pmid:22538527 |
| Rao MS et al. | Yield, protein, and oil quality of soybean genotypes selected for tofu production. | 1998 | Plant Foods Hum Nutr | pmid:9950085 |
| Baudouin E et al. | Short communication: unsaturated fatty acids inhibit MP2C, a protein phosphatase 2C involved in the wound-induced MAP kinase pathway regulation. | 1999 | Plant J. | pmid:10571894 |
| O'Neill CM et al. | Two high linolenic mutants of Arabidopsis thaliana contain megabase-scale genome duplications encompassing the FAD3 locus. | 2011 | Plant J. | pmid:21848868 |
| Kajikawa M et al. | Isolation and characterization of delta(6)-desaturase, an ELO-like enzyme and delta(5)-desaturase from the liverwort Marchantia polymorpha and production of arachidonic and eicosapentaenoic acids in the methylotrophic yeast Pichia pastoris. | 2004 | Plant Mol. Biol. | pmid:15284491 |
| Mariutto M et al. | Reprogramming of fatty acid and oxylipin synthesis in rhizobacteria-induced systemic resistance in tomato. | 2014 | Plant Mol. Biol. | pmid:24146221 |
| Kaup MT et al. | A role for diacylglycerol acyltransferase during leaf senescence. | 2002 | Plant Physiol. | pmid:12177474 |
| Schmelz EA et al. | Nitrogen deficiency increases volicitin-induced volatile emission, jasmonic acid accumulation, and ethylene sensitivity in maize. | 2003 | Plant Physiol. | pmid:12970495 |
| Fraser TC et al. | Expression of the Isochrysis C18-delta9 polyunsaturated fatty acid specific elongase component alters Arabidopsis glycerolipid profiles. | 2004 | Plant Physiol. | pmid:15173563 |
| Koch T et al. | Differential induction of plant volatile biosynthesis in the lima bean by early and late intermediates of the octadecanoid-signaling pathway. | 1999 | Plant Physiol. | pmid:10482670 |
| Maffei M et al. | Effects of feeding Spodoptera littoralis on lima bean leaves. I. Membrane potentials, intracellular calcium variations, oral secretions, and regurgitate components. | 2004 | Plant Physiol. | pmid:15051862 |
| Shimada TL et al. | Leaf oil body functions as a subcellular factory for the production of a phytoalexin in Arabidopsis. | 2014 | Plant Physiol. | pmid:24214535 |
| von Berlepsch S et al. | The acyl-acyl carrier protein synthetase from Synechocystis sp. PCC 6803 mediates fatty acid import. | 2012 | Plant Physiol. | pmid:22535424 |
| Clemente TE and Cahoon EB | Soybean oil: genetic approaches for modification of functionality and total content. | 2009 | Plant Physiol. | pmid:19783644 |
| Qi J et al. | The chloroplast-localized phospholipases D α4 and α5 regulate herbivore-induced direct and indirect defenses in rice. | 2011 | Plant Physiol. | pmid:21984727 |
| Cahoon EB et al. | Transgenic production of epoxy fatty acids by expression of a cytochrome P450 enzyme from Euphorbia lagascae seed. | 2002 | Plant Physiol. | pmid:11842164 |
| Vrinten P et al. | Two FAD3 desaturase genes control the level of linolenic acid in flax seed. | 2005 | Plant Physiol. | pmid:16113219 |
| Marmon S et al. | Two Acyltransferases Contribute Differently to Linolenic Acid Levels in Seed Oil. | 2017 | Plant Physiol. | pmid:28235891 |
| Vigeolas H et al. | Nonsymbiotic hemoglobin-2 leads to an elevated energy state and to a combined increase in polyunsaturated fatty acids and total oil content when overexpressed in developing seeds of transgenic Arabidopsis plants. | 2011 | Plant Physiol. | pmid:21205621 |
| DomÃnguez T et al. | Increasing omega-3 desaturase expression in tomato results in altered aroma profile and enhanced resistance to cold stress. | 2010 | Plant Physiol. | pmid:20382895 |
| Mata-Pérez C et al. | Nitro-Fatty Acids in Plant Signaling: Nitro-Linolenic Acid Induces the Molecular Chaperone Network in Arabidopsis. | 2016 | Plant Physiol. | pmid:26628746 |
| Norton G et al. | Characterisation of recombinant Hevea brasiliensis allene oxide synthase: effects of cycloxygenase inhibitors, lipoxygenase inhibitors and salicylates on enzyme activity. | 2007 | Plant Physiol. Biochem. | pmid:17344058 |
| Zhang HY et al. | Isolation and functional assessment of a tomato proteinase inhibitor II gene. | 2004 | Plant Physiol. Biochem. | pmid:15191748 |
| Afitlhile M et al. | A mutant of the Arabidopsis thaliana TOC159 gene accumulates reduced levels of linolenic acid and monogalactosyldiacylglycerol. | 2013 | Plant Physiol. Biochem. | pmid:24184455 |
| Yamauchi Y et al. | Malondialdehyde generated from peroxidized linolenic acid causes protein modification in heat-stressed plants. | 2008 Aug-Sep | Plant Physiol. Biochem. | pmid:18538576 |
| Chua AC et al. | Characterization of oil bodies in jelly fig achenes. | 2008 May-Jun | Plant Physiol. Biochem. | pmid:18434174 |
| Berkov S et al. | Changes in apolar metabolites during in vitro organogenesis of Pancratium maritimum. | 2010 Oct-Nov | Plant Physiol. Biochem. | pmid:20702100 |
| Lorenzi V et al. | Purification, product characterization and kinetic properties of lipoxygenase from olive fruit (Olea europaea L.). | 2006 Jul-Sep | Plant Physiol. Biochem. | pmid:17011785 |
| Venegas-Calerón M et al. | Effect of the ferredoxin electron donor on sunflower (Helianthus annuus) desaturases. | 2009 | Plant Physiol. Biochem. | pmid:19342250 |
| Li T et al. | Defense priming by non-jasmonate producing fatty acids in maize (Zea mays). | 2016 | Plant Signal Behav | pmid:27763804 |
| Seltmann MA et al. | Jasmonates during senescence: signals or products of metabolism? | 2010 | Plant Signal Behav | pmid:21057217 |
| Truitt CL and Paré PW | In situ translocation of volicitin by beet armyworm larvae to maize and systemic immobility of the herbivore elicitor in planta. | 2004 | Planta | pmid:14685859 |
| Schmelz EA et al. | The influence of intact-plant and excised-leaf bioassay designs on volicitin- and jasmonic acid-induced sesquiterpene volatile release in Zea mays. | 2001 | Planta | pmid:11800380 |
| Deng YM et al. | Anti-asthmatic effects of Perilla seed oil in the guinea pig in vitro and in vivo. | 2007 | Planta Med. | pmid:17315310 |
| Mohn T et al. | Quantification of active principles and pigments in leaf extracts of Isatis tinctoria by HPLC/UV/MS. | 2007 | Planta Med. | pmid:17236114 |