alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

Cross Reference

Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Amyloidosis D000686 4 associated lipids
Aortic Diseases D001018 11 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Birth Weight D001724 23 associated lipids
Urinary Bladder Neoplasms D001749 7 associated lipids
Body Weight D001835 333 associated lipids
Breast Neoplasms D001943 24 associated lipids
Bronchial Spasm D001986 18 associated lipids
Cat Diseases D002371 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Brain Ischemia D002545 89 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Conjunctivitis, Allergic D003233 1 associated lipids
Per page 10 20 50 100 | Total 104

PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 2471
Authors Title Published Journal PubMed Link
Mantzioris E et al. Nutritional attributes of dietary flaxseed oil. 1995 Am. J. Clin. Nutr. pmid:7572718
Romans JR et al. Effects of ground flaxseed in swine diets on pig performance and on physical and sensory characteristics and omega-3 fatty acid content of pork: I. Dietary level of flaxseed. 1995 J. Anim. Sci. pmid:7592082
Wijkander J et al. 5-Lipoxygenase products modulate the activity of the 85-kDa phospholipase A2 in human neutrophils. 1995 J. Biol. Chem. pmid:7592874
Nordström DC et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. 1995 Rheumatol. Int. pmid:7597378
Ferrier LK et al. alpha-Linolenic acid- and docosahexaenoic acid-enriched eggs from hens fed flaxseed: influence on blood lipids and platelet phospholipid fatty acids in humans. 1995 Am. J. Clin. Nutr. pmid:7598070
Lok E et al. The effect of different levels of dietary alpha-linolenic and other fatty acids on mammary gland ductular cell proliferation in female Swiss Webster mice. 1995 Cancer Lett. pmid:7600535
Sugihara N et al. High susceptibility to paraquat-driven lipid peroxidation of cultured hepatocytes loaded with linolenic acid. 1995 J. Pharmacol. Exp. Ther. pmid:7616398
Krugliak M et al. Antimalarial effects of C18 fatty acids on Plasmodium falciparum in culture and on Plasmodium vinckei petteri and Plasmodium yoelii nigeriensis in vivo. 1995 Exp. Parasitol. pmid:7628573
Emmison N et al. Linoleic and linolenic acids are selectively secreted in triacylglycerol by hepatocytes from neonatal rats. 1995 Am. J. Physiol. pmid:7631907
Weisinger HS et al. Dietary manipulation of long-chain polyunsaturated fatty acids in the retina and brain of guinea pigs. 1995 Lipids pmid:7637569
Guo W and Hamilton JA Phase behavior and crystalline structures of cholesteryl ester mixtures: a C-13 MASNMR study. 1995 Biophys. J. pmid:7647242
Tezabwala BU et al. Immunotoxicity of polyunsaturated fatty acids in serum-free medium. 1995 Immunopharmacol Immunotoxicol pmid:7650296
Sheaff RC et al. Conversion of alpha-linolenate to docosahexaenoate is not depressed by high dietary levels of linoleate in young rats: tracer evidence using high precision mass spectrometry. 1995 J. Lipid Res. pmid:7658170
Grechkin AN et al. The lipoxygenase pathway in garlic (Allium sativum L.) bulbs: detection of the novel divinyl ether oxylipins. 1995 FEBS Lett. pmid:7672118
Saito M Effect of dietary alpha-linolenic, eicosapentaenoic and docosahexaenoic acids on liver microsomal mixed-function oxidases in rats. 1994 Ann. Nutr. Metab. pmid:7702359
Smuts CM et al. The effect of iron fortification on the fatty acid composition of plasma and erythrocyte membranes in primary school children with and without iron deficiency. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7708822
Saradhi PP et al. Proline accumulates in plants exposed to UV radiation and protects them against UV induced peroxidation. 1995 Biochem. Biophys. Res. Commun. pmid:7726821
Kang JX et al. Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7732020
Degousée N et al. Measurement of thermally produced volatile alkanes: an assay for plant hydroperoxy fatty acid evaluation. 1995 Anal. Biochem. pmid:7733454
Uauy-Dagach R et al. Essential fatty acid metabolism and requirements for LBW infants. 1994 Acta Paediatr Suppl pmid:7734797
Decsi T et al. Essential fatty acids in full term infants fed breast milk or formula. 1995 Arch. Dis. Child. Fetal Neonatal Ed. pmid:7743279
Numata M [Antitumor effects of alpha-linolenic acid on the human tumor transplanted in nude mice and on the metastasis of Vx-7 tumor in rabbit]. 1995 Hokkaido Igaku Zasshi pmid:7744366
Kumar GS and Das UN Free radical-dependent suppression of growth of mouse myeloma cells by alpha-linolenic and eicosapentaenoic acids in vitro. 1995 Cancer Lett. pmid:7757958
Kirmani ZA et al. Effects of supplemented omega-3 and omega-6 fatty acid rich oils on the cardiovascular system of thermally injured rabbits: changes in plasma and platelet fatty acids. 1995 Mar-Apr J Burn Care Rehabil pmid:7775514
Cunnane SC et al. Nutritional attributes of traditional flaxseed in healthy young adults. 1995 Am. J. Clin. Nutr. pmid:7825540
Oulhaj H et al. [Utilization of linoleate and alpha-linolenate in peritubular cells and Sertoli cells in culture]. 1994 C. R. Seances Soc. Biol. Fil. pmid:7834508
Mantzioris E et al. Differences exist in the relationships between dietary linoleic and alpha-linolenic acids and their respective long-chain metabolites. 1995 Am. J. Clin. Nutr. pmid:7840069
Ghafoorunissa Dietary lipids and heart disease--the Indian context. 1994 Nov-Dec Natl Med J India pmid:7841878
Yuasa H et al. Gastric emptying-limited oral absorption of alpha-linolenic acid administered as a milk fat-globule membrane (MFGM) emulsion in rats. 1994 Biol. Pharm. Bull. pmid:7841950
Ingram AJ et al. Effects of flaxseed and flax oil diets in a rat-5/6 renal ablation model. 1995 Am. J. Kidney Dis. pmid:7847360
Kojima S et al. Antioxidative activity of benzylideneascorbate and its effect on adriamycin-induced cardiotoxicity. 1994 Sep-Oct Anticancer Res. pmid:7847820
Goré J et al. Linoleic acid uptake by isolated enterocytes: influence of alpha-linolenic acid on absorption. 1994 Lipids pmid:7861937
Chen ZY et al. Moderate, selective depletion of linoleate and alpha-linolenate in weight-cycled rats. 1995 Am. J. Physiol. pmid:7864247
Lawrence JF et al. An incident of elevated levels of unsaturated free fatty acids in mussels from Nova Scotia and their toxic effect in mice after intraperitoneal injection. 1994 Nat. Toxins pmid:7866668
Pawlosky R et al. Essential fatty acid metabolism in the feline: relationship between liver and brain production of long-chain polyunsaturated fatty acids. 1994 J. Lipid Res. pmid:7868981
Moore SA Local synthesis and targeting of essential fatty acids at the cellular interface between blood and brain: a role for cerebral endothelium and astrocytes in the accretion of CNS docosahexaenoic acid. 1994 World Rev Nutr Diet pmid:7871814
Santos MJ et al. Influence of dietary supplementation with fish on plasma fatty acid composition in coronary heart disease patients. 1995 Ann. Nutr. Metab. pmid:7872656
Kardinaal AF et al. Relations between antioxidant vitamins in adipose tissue, plasma, and diet. 1995 Am. J. Epidemiol. pmid:7879788
Yehuda S and Carasso RL Modulation of learning, pain thresholds, and thermoregulation in the rat by preparations of free purified alpha-linolenic and linoleic acids: determination of the optimal omega 3-to-omega 6 ratio. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:7901853
Wang N and Anderson RE Synthesis of docosahexaenoic acid by retina and retinal pigment epithelium. 1993 Biochemistry pmid:7903049
Cao J et al. Inhibition of fatty acid delta 6- and delta 5-desaturation by cyclopropene fatty acids in rat liver microsomes. 1993 Biochim. Biophys. Acta pmid:7903050
Bierenbaum ML et al. Reducing atherogenic risk in hyperlipemic humans with flax seed supplementation: a preliminary report. 1993 J Am Coll Nutr pmid:7903324
Carter J Flax seed as a source of alpha linolenic acid. 1993 J Am Coll Nutr pmid:7903325
Tang AB et al. Preferential reduction in adipose tissue alpha-linolenic acid (18:3 omega 3) during very low calorie dieting despite supplementation with 18:3 omega 3. 1993 Lipids pmid:7904040
Green P and Yavin E Elongation, desaturation, and esterification of essential fatty acids by fetal rat brain in vivo. 1993 J. Lipid Res. pmid:7905509
Regdel D et al. On the reaction specificity of the lipoxygenase from tomato fruits. 1994 Biochim. Biophys. Acta pmid:7905748
Jiang Z and Sim JS Consumption of n-3 polyunsaturated fatty acid-enriched eggs and changes in plasma lipids of human subjects. 1993 Nov-Dec Nutrition pmid:7906572
Saad Aida MA et al. Role of dietary lipids and butylated hydroxy anisol (BHA) administration on albino rats. Part I. Serum unsaturated fatty acids. 1993 Nahrung pmid:7907168
Okuley J et al. Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis. 1994 Plant Cell pmid:7907506
Lockwood K et al. Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10. 1994 Biochem. Biophys. Res. Commun. pmid:7908519