alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Amyloidosis D000686 4 associated lipids
Aortic Diseases D001018 11 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Birth Weight D001724 23 associated lipids
Urinary Bladder Neoplasms D001749 7 associated lipids
Body Weight D001835 333 associated lipids
Breast Neoplasms D001943 24 associated lipids
Bronchial Spasm D001986 18 associated lipids
Cat Diseases D002371 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Brain Ischemia D002545 89 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Conjunctivitis, Allergic D003233 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Ponnampalam EN et al. Health beneficial long chain omega-3 fatty acid levels in Australian lamb managed under extensive finishing systems. 2014 Meat Sci. pmid:23643471
De Mel D and Suphioglu C Fishy business: effect of omega-3 fatty acids on zinc transporters and free zinc availability in human neuronal cells. 2014 Nutrients pmid:25195602
Fretts AM et al. Plasma phospholipid and dietary α-linolenic acid, mortality, CHD and stroke: the Cardiovascular Health Study. 2014 Br. J. Nutr. pmid:25159901
Villar-Tajadura MA et al. Production of conjugated linoleic and conjugated α-linolenic acid in a reconstituted skim milk-based medium by bifidobacterial strains isolated from human breast milk. 2014 Biomed Res Int pmid:25110689
Hoogeveen EK et al. Effect of omega-3 fatty acids on kidney function after myocardial infarction: the Alpha Omega Trial. 2014 Clin J Am Soc Nephrol pmid:25104273
Hwang E et al. Coriander leaf extract exerts antioxidant activity and protects against UVB-induced photoaging of skin by regulation of procollagen type I and MMP-1 expression. 2014 J Med Food pmid:25019675
dos Santos AL et al. Dietary fat composition and cardiac events in patients with type 2 diabetes. 2014 Atherosclerosis pmid:25014032
Eisinger K et al. Lipidomic analysis of the liver from high-fat diet induced obese mice identifies changes in multiple lipid classes. 2014 Exp. Mol. Pathol. pmid:24830603
Marklund M et al. A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy Nordic diet in individuals with metabolic syndrome. 2014 J. Nutr. pmid:25080537
Purushothaman D et al. Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs. 2014 Genet. Mol. Res. pmid:25078588
Hellstrand S et al. Genetic variation in FADS1 has little effect on the association between dietary PUFA intake and cardiovascular disease. 2014 J. Nutr. pmid:25008580
Lane K et al. Bioavailability and potential uses of vegetarian sources of omega-3 fatty acids: a review of the literature. 2014 Crit Rev Food Sci Nutr pmid:24261532
Carbonera F et al. Effect of dietary replacement of sunflower oil with perilla oil on the absolute fatty acid composition in Nile tilapia (GIFT). 2014 Food Chem pmid:24262550
Morris JB et al. Flavonol content, oil%, and fatty acid composition variability in seeds of Teramnus labialis and T. uncinatus accessions with nutraceutical potential. 2014 J Diet Suppl pmid:25054688
Martínez-Ramírez HR et al. Retention of n-3 polyunsaturated fatty acids in trimmed loin and belly is independent of timing of feeding ground flaxseed to growing-finishing female pigs. 2014 J. Anim. Sci. pmid:24305874
Gong Z et al. G protein-coupled receptor 120 signaling regulates ghrelin secretion in vivo and in vitro. 2014 Am. J. Physiol. Endocrinol. Metab. pmid:24222669
Sánchez-Reyes OB et al. Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation. 2014 Eur. J. Pharmacol. pmid:24239485
Berasategi I et al. Healthy reduced-fat Bologna sausages enriched in ALA and DHA and stabilized with Melissa officinalis extract. 2014 Meat Sci. pmid:24334039
Sengupta A and Ghosh M Effect of sterol esters on lipid composition and antioxidant status of erythrocyte membrane of hypercholesterolemic rats. 2014 J Oleo Sci pmid:24770475
Yuan X et al. Accumulation of eicosapolyenoic acids enhances sensitivity to abscisic acid and mitigates the effects of drought in transgenic Arabidopsis thaliana. 2014 J. Exp. Bot. pmid:24609499