| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Amyloidosis | D000686 | 4 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Urinary Bladder Neoplasms | D001749 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Cat Diseases | D002371 | 12 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Conjunctivitis, Allergic | D003233 | 1 associated lipids |
alpha-linolenic acid
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
Cross Reference
Introduction
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with alpha-linolenic acid?
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with alpha-linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with alpha-linolenic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with alpha-linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with alpha-linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Coté GG and Brody S | Circadian rhythms in Neurospora crassa: a clock mutant, prd-1, is altered in membrane fatty acid composition. | 1987 | Biochim. Biophys. Acta | pmid:2889471 |
| Takahashi R et al. | Impaired platelet aggregation and thromboxane generation in essential fatty acid-deficient rats. | 1987 | J. Nutr. | pmid:2888839 |
| Singer P et al. | Changes of N-6 and N-3 fatty acids in liver from spontaneously hypertensive (SHR) and normotensive rats after diets supplemented with alpha-linolenic or eicosapentaenoic acids. | 1987 | Prostaglandins Leukot Med | pmid:2888133 |
| pmid:28880969 | ||||
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| pmid:28851088 | ||||
| Bursztyn P | Does dietary linolenic acid influence blood pressure? | 1987 | Am. J. Clin. Nutr. | pmid:2884863 |
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| Bjerve KS | Alpha-linolenic acid deficiency in adult women. | 1987 | Nutr. Rev. | pmid:2881237 |
| Gotoh K et al. | Effects of unsaturated fatty acids on the peroxisomal enzyme activities of Tetrahymena pyriformis. | 1986 | J. Biochem. | pmid:2880840 |
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| Gutteridge JM | The antioxidant activity of haptoglobin towards haemoglobin-stimulated lipid peroxidation. | 1987 | Biochim. Biophys. Acta | pmid:2879568 |
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| Anding RH and Hwang DH | Effects of dietary linolenate on the fatty acid composition of brain lipids in rats. | 1986 | Lipids | pmid:2879208 |
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| Nutrition classics. Lipids, June 1979 Volume 14, No. 6: Reproduction and survival of rainbow trout (Salmo gairdneri) fed linolenic acid as the only source of essential fatty acids. By T.C. Yu, R.O. Sinnhuber, and J.D. Hendricks. | 1986 | Nutr. Rev. | pmid:2878402 | |
| Hiltunen JK et al. | beta-Oxidation of polyunsaturated fatty acids by rat liver peroxisomes. A role for 2,4-dienoyl-coenzyme A reductase in peroxisomal beta-oxidation. | 1986 | J. Biol. Chem. | pmid:2877988 |
| Guesnet P et al. | Dietary alpha-linolenic acid deficiency in the rat. I. Effects on reproduction and postnatal growth. | 1986 | Reprod Nutr Dev | pmid:2877477 |
| Acosta PB and Stepnick-Gropper S | Problems related to diet management of maternal phenylketonuria. | 1986 | J. Inherit. Metab. Dis. | pmid:2877116 |
| Nakamoto S et al. | Lipid peroxidation and cytotoxicity of Ehrlich ascites tumor cells by ferric nitrilotriacetate. | 1986 | Biochim. Biophys. Acta | pmid:2876731 |
| pmid:28764049 | ||||
| Nouvelot A et al. | Hepatic metabolism of dietary alpha-linolenic acid in suckling rats, and its possible importance in polyunsaturated fatty acid uptake by the brain. | 1986 | Ann. Nutr. Metab. | pmid:2875687 |
| Berry EM and Hirsch J | Does dietary linolenic acid influence blood pressure? | 1986 | Am. J. Clin. Nutr. | pmid:2875645 |
| Towell JF | An animated graphics program depicting the steps in lipid peroxidation. | 1985 | J Free Radic Biol Med | pmid:2875091 |
| Takahashi K et al. | Polyethylene glycol-modified hemin having peroxidase activity in organic solvents. | 1986 | Biochem. Biophys. Res. Commun. | pmid:2874801 |
| Adam O et al. | Effect of alpha-linolenic acid in the human diet on linoleic acid metabolism and prostaglandin biosynthesis. | 1986 | J. Lipid Res. | pmid:2873197 |
| Carlin G | Peroxidation of linolenic acid promoted by human polymorphonuclear leucocytes. | 1985 | J Free Radic Biol Med | pmid:2873164 |
| Jenkins KJ and Kramer JK | Influence of low linoleic and linolenic acids in milk replacer on calf performance and lipids in blood plasma, heart, and liver. | 1986 | J. Dairy Sci. | pmid:2873158 |
| Meadows J et al. | Uric acid protects membranes and linolenic acid from ozone-induced oxidation. | 1986 | Biochem. Biophys. Res. Commun. | pmid:2872893 |
| Leat WM et al. | Retinal function in rats and guinea-pigs reared on diets low in essential fatty acids and supplemented with linoleic or linolenic acids. | 1986 | Ann. Nutr. Metab. | pmid:2872851 |
| Cholesterol metabolism and omega-3 polyenes in fish oils. | 1986 | Nutr. Rev. | pmid:2872641 | |
| Dyerberg J | Linolenate-derived polyunsaturated fatty acids and prevention of atherosclerosis. | 1986 | Nutr. Rev. | pmid:2872640 |
| Hagve TA et al. | Desaturation and chain elongation of essential fatty acids in isolated liver cells from rat and rainbow trout. | 1986 | Lipids | pmid:2871473 |
| Carlson SE et al. | High fat diets varying in ratios of polyunsaturated to saturated fatty acid and linoleic to linolenic acid: a comparison of rat neural and red cell membrane phospholipids. | 1986 | J. Nutr. | pmid:2871142 |
| pmid:28703829 | ||||
| Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |
| Leikin AI and Brenner RR | Regulation of linoleic acid delta 6-desaturation by a cytosolic lipoprotein-like fraction in isolated rat liver microsomes. | 1986 | Biochim. Biophys. Acta | pmid:2869785 |
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| Pisanti FA et al. | Effects of bonellin on lipids. | 1986 | Life Sci. | pmid:2869393 |
| Siegel I et al. | Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. | 1986 | Fertil. Steril. | pmid:2868925 |
| Booyens J et al. | Chronic arachidonic acid eicosanoid imbalance: a common feature in coronary artery disease, hypercholesterolemia, cancer and other important diseases. Significance of desaturase enzyme inhibition and of the arachidonic acid desaturase-independent pathway. | 1985 | Med. Hypotheses | pmid:2866439 |
| pmid:28660529 | ||||
| Stymne S and Stobart AK | Involvement of acyl exchange between acyl-CoA and phosphatidylcholine in the remodelling of phosphatidylcholine in microsomal preparations of rat lung. | 1985 | Biochim. Biophys. Acta | pmid:2865978 |