Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gutteridge JM | The antioxidant activity of haptoglobin towards haemoglobin-stimulated lipid peroxidation. | 1987 | Biochim. Biophys. Acta | pmid:2879568 |
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Bjerve KS | Alpha-linolenic acid deficiency in adult women. | 1987 | Nutr. Rev. | pmid:2881237 |
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McDonald GB and Weidman M | Partitioning of polar fatty acids into lymph and portal vein after intestinal absorption in the rat. | 1987 | Q J Exp Physiol | pmid:2884690 |
Bursztyn P | Does dietary linolenic acid influence blood pressure? | 1987 | Am. J. Clin. Nutr. | pmid:2884863 |
pmid:28851088 | ||||
Vrignaud P and Robert J | Free fatty acid uptake is increased in doxorubicin-resistant rat glioblastoma cells. | 1987 | Biochim. Biophys. Acta | pmid:2886153 |
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pmid:28880969 | ||||
Singer P et al. | Changes of N-6 and N-3 fatty acids in liver from spontaneously hypertensive (SHR) and normotensive rats after diets supplemented with alpha-linolenic or eicosapentaenoic acids. | 1987 | Prostaglandins Leukot Med | pmid:2888133 |
Takahashi R et al. | Impaired platelet aggregation and thromboxane generation in essential fatty acid-deficient rats. | 1987 | J. Nutr. | pmid:2888839 |
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Zöllner N | Dietary linolenic acid in man--an overview. | 1986 | Prog. Lipid Res. | pmid:2892211 |
Sanders TA and Rana SK | Comparison of the metabolism of linoleic and linolenic acids in the fetal rat. | 1987 | Ann. Nutr. Metab. | pmid:2892461 |
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Chander A and Fisher AB | Choline-phosphate cytidyltransferase activity and phosphatidylcholine synthesis in rat granular pneumocytes are increased with exogenous fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:2893643 |
Hwang DH et al. | Dietary linolenic acid and longer-chain n-3 fatty acids: comparison of effects on arachidonic acid metabolism in rats. | 1988 | J. Nutr. | pmid:2895804 |
pmid:28965514 | ||||
Arthur JR | Effects of selenium and vitamin E status on plasma creatine kinase activity in calves. | 1988 | J. Nutr. | pmid:2897437 |
Astorg PO and Chevalier J | Polyunsaturated fatty acids in tissues of rats fed trielaidin and high or low levels of linolenic acid. | 1987 | Lipids | pmid:2897610 |
Guesnet P et al. | Effects of dietary alpha-linolenic acid deficiency during pregnancy and lactation on lipid fatty acid composition of liver and serum in the rat. | 1988 | Reprod Nutr Dev | pmid:2897705 |
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Homayoun P et al. | Alteration in fatty acid composition of adult rat brain capillaries and choroid plexus induced by a diet deficient in n-3 fatty acids: slow recovery after substitution with a nondeficient diet. | 1988 | J. Neurochem. | pmid:2898007 |
Huang YS et al. | Selective incorporation of n-3 and n-6 fatty acids in essential fatty acid deficient rats in response to short-term oil feeding. | 1987 | Biochem. Int. | pmid:2898942 |
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Garg ML et al. | Dietary cholesterol and/or n-3 fatty acid modulate delta 9-desaturase activity in rat liver microsomes. | 1988 | Biochim. Biophys. Acta | pmid:2901857 |
Yamamoto N et al. | Effect of the dietary alpha-linolenate/linoleate balance on lipid compositions and learning ability of rats. II. Discrimination process, extinction process, and glycolipid compositions. | 1988 | J. Lipid Res. | pmid:2903207 |
Choi YS and Sugano M | Effects of dietary alpha- and gamma-linolenic acid on lipid metabolism in young and adult rats. | 1988 | Ann. Nutr. Metab. | pmid:2903713 |
Khokher MA and Dandona P | The effect of polyunsaturated fatty acids on rat adipocyte lipogenesis: the role of protein kinase C, calcium and calmodulin. | 1988 | Diabetes Res. | pmid:2906578 |
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pmid:29232610 | ||||
pmid:29311522 | ||||
pmid:29407798 | ||||
pmid:29459511 | ||||
Jones DB et al. | Glucose, insulin and platelet fatty acids following myocardial infarction: an association with infarct size. | 1987 Jul-Aug | Diabete Metab | pmid:3315767 |
Furukawa M et al. | Studies on arachidonate 5-lipoxygenase of rat basophilic leukemia cells. | 1984 | Biochim. Biophys. Acta | pmid:6089906 |