Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Sugano M and Ikeda I | Metabolic interactions between essential and trans-fatty acids. | 1996 | Curr. Opin. Lipidol. | pmid:8925188 |
Mutanen M and Freese R | Polyunsaturated fatty acids and platelet aggregation. | 1996 | Curr. Opin. Lipidol. | pmid:8925182 |
Mensink R | Essential and trans-fatty acids. | 1996 | Curr. Opin. Lipidol. | pmid:8925181 |
Woods J et al. | Is docosahexaenoic acid necessary in infant formula? Evaluation of high linolenate diets in the neonatal rat. | 1996 | Pediatr. Res. | pmid:8910933 |
Cunnane SC and Likhodii SS | 13C NMR spectroscopy and gas chromatograph--combustion--isotope ratio mass spectrometry: complementary applications in monitoring the metabolism of 13C-labelled polyunsaturated fatty acids. | 1996 | Can. J. Physiol. Pharmacol. | pmid:8909789 |
Cunnane SC | The Canadian Society for Nutritional Sciences 1995 Young Scientist Award Lecture. Recent studies on the synthesis, beta-oxidation, and deficiency of linoleate and alpha-linolenate: are essential fatty acids more aptly named indispensable or conditionally dispensable fatty acids? | 1996 | Can. J. Physiol. Pharmacol. | pmid:8909772 |
Rupp H et al. | Dietary linolenic acid-mediated increase in vascular prostacyclin formation. | 1996 | Mol. Cell. Biochem. | pmid:8905626 |
Kawano Y and Noma T | Inhibition by lecithin-bound iodine (LBI) of inducible allergen-specific T lymphocytes' responses in allergic diseases. | 1996 | Int. J. Immunopharmacol. | pmid:8894803 |
Scheideler SE and Froning GW | The combined influence of dietary flaxseed variety, level, form, and storage conditions on egg production and composition among vitamin E-supplemented hens. | 1996 | Poult. Sci. | pmid:8893298 |
Conconi A et al. | The octadecanoid signalling pathway in plants mediates a response to ultraviolet radiation. | 1996 | Nature | pmid:8893008 |
Klein AS et al. | Allopurinol: discrimination of antioxidant from enzyme inhibitory activities. | 1996 | Free Radic. Biol. Med. | pmid:8891675 |
Luukkainen P et al. | Impact of solid food on plasma arachidonic and docosahexaenoic acid status of term infants at 8 months of age. | 1996 | J. Pediatr. Gastroenterol. Nutr. | pmid:8890071 |
Ovesen L et al. | The effect of microwave heating on vitamins B1 and E, and linoleic and linolenic acids, and immunoglobulins in human milk. | 1996 | Int J Food Sci Nutr | pmid:8889628 |
Ferretti A and Flanagan VP | Antithromboxane activity of dietary alpha-linolenic acid: a pilot study. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888358 |
Inui K et al. | The nutritional effect of a-linolenic acid-rich emulsion with total parenteral nutrition in a rat model with inflammatory bowel disease. | 1996 | Ann. Nutr. Metab. | pmid:8886251 |
Leece EA and Allman MA | The relationships between dietary alpha-linolenic:linoleic acid and rat platelet eicosapentaenoic and arachidonic acids. | 1996 | Br. J. Nutr. | pmid:8881716 |
Schingoethe DJ et al. | Lactational responses of dairy cows fed unsaturated fat from extruded soybeans or sunflower seeds. | 1996 | J. Dairy Sci. | pmid:8872718 |
Inui K et al. | The effect of alpha-linolenic acid-rich emulsion on fatty acid metabolism and leukotriene generation of the colon in a rat model with inflammatory bowel disease. | 1996 | Ann. Nutr. Metab. | pmid:8862700 |
Hudson JA et al. | Hydration of oleic acid by a Selenomonas strain from the ovine rumen. | 1996 | Lett. Appl. Microbiol. | pmid:8862016 |
Venuta A et al. | Essential fatty acids: the effects of dietary supplementation among children with recurrent respiratory infections. | 1996 Jul-Aug | J. Int. Med. Res. | pmid:8854285 |
Francès H et al. | Influence of a dietary alpha-linolenic acid deficiency on learning in the Morris water maze and on the effects of morphine. | 1996 | Eur. J. Pharmacol. | pmid:8846819 |
Organisciak DT et al. | Retinal light damage in rats with altered levels of rod outer segment docosahexaenoate. | 1996 | Invest. Ophthalmol. Vis. Sci. | pmid:8843911 |
Fukui H et al. | 0/w-emulsion of alpha-linolenic acid stabilized with hydrophobized polysaccharide. Its effect on the growth of human colon cancer cells. | 1996 | J Biomater Sci Polym Ed | pmid:8836830 |
Chardigny JM et al. | Identification of novel trans isomers of 20:5n-3 in liver lipids of rats fed a heated oil. | 1996 | Lipids | pmid:8835404 |
Engberg RM et al. | Inclusion of oxidized vegetable oil in broiler diets. Its influence on nutrient balance and on the antioxidative status of broilers. | 1996 | Poult. Sci. | pmid:8829233 |
Komaki C et al. | Synergistic suppression of azoxymethane-induced foci of colonic aberrant crypts by the combination of beta-carotene and perilla oil in rats. | 1996 | Carcinogenesis | pmid:8824511 |
Carnielli VP et al. | The very low birth weight premature infant is capable of synthesizing arachidonic and docosahexaenoic acids from linoleic and linolenic acids. | 1996 | Pediatr. Res. | pmid:8798265 |
Dalençon F et al. | Liposomes bearing platelet proteins: a model for surface functions studies. | 1996 | Biochim. Biophys. Acta | pmid:8765146 |
Do TQ et al. | Enhanced sensitivity of ubiquinone-deficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8755509 |
Ikeda A et al. | Effects of intravenous perilla oil emulsion on nutritional status, polyunsaturated fatty acid composition of tissue phospholipids, and thromboxane A2 production in streptozotocin-induced diabetic rats. | 1995 Sep-Oct | Nutrition | pmid:8748197 |
Valsta LM et al. | Alpha-linolenic acid in rapeseed oil partly compensates for the effect of fish restriction on plasma long chain n-3 fatty acids. | 1996 | Eur J Clin Nutr | pmid:8730609 |
Waters KM and Ntambi JM | Polyunsaturated fatty acids inhibit hepatic stearoyl-CoA desaturase-1 gene in diabetic mice. | 1996 | Lipids | pmid:8729090 |
Ide T et al. | Stimulation of the activities of hepatic fatty acid oxidation enzymes by dietary fat rich in alpha-linolenic acid in rats. | 1996 | J. Lipid Res. | pmid:8728310 |
Lim BO et al. | Effects of n-3 polyunsaturated fatty acids and lectins on immunoglobulin production by spleen lymphocytes of Sprague-Dawley rats. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8695902 |
Carnielli VP et al. | Medium-chain triacylglycerols in formulas for preterm infants: effect on plasma lipids, circulating concentrations of medium-chain fatty acids, and essential fatty acids. | 1996 | Am. J. Clin. Nutr. | pmid:8694014 |
Sadi AM et al. | Dietary effects of corn oil, oleic acid, perilla oil, and evening [corrected] primrose oil on plasma and hepatic lipid level and atherosclerosis in Japanese quail. | 1996 | Exp. Anim. | pmid:8689581 |
Ascherio A et al. | Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States. | 1996 | BMJ | pmid:8688759 |
Onogi N et al. | Suppressing effect of perilla oil on azoxymethane-induced foci of colonic aberrant crypts in rats. | 1996 | Carcinogenesis | pmid:8681445 |
Van Nevel C and Demeyer DI | Lipolysis and biohydrogenation of soybean oil in the rumen in vitro: inhibition by antimicrobials. | 1995 | J. Dairy Sci. | pmid:8675762 |
Chen ZY et al. | Accumulation of polyunsaturates is decreased by weight-cycling: whole-body analysis in young, growing rats. | 1996 | Br. J. Nutr. | pmid:8672410 |
Moore SA et al. | Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid. | 1995 | J. Lipid Res. | pmid:8656081 |
Furono K et al. | Effects of metal ions on lipid peroxidation in cultured rat hepatocytes loaded with alpha-linolenic acid. | 1996 | J Toxicol Environ Health | pmid:8642620 |
Frances H et al. | Effect of dietary alpha-linolenic acid deficiency on habituation. | 1996 | Life Sci. | pmid:8637406 |
Delion S et al. | alpha-Linolenic acid dietary deficiency alters age-related changes of dopaminergic and serotoninergic neurotransmission in the rat frontal cortex. | 1996 | J. Neurochem. | pmid:8627314 |
Carlson SE et al. | Effect of long-chain n-3 fatty acid supplementation on visual acuity and growth of preterm infants with and without bronchopulmonary dysplasia. | 1996 | Am. J. Clin. Nutr. | pmid:8615350 |
Lhuillery C et al. | Time-course study of adipose tissue fatty acid composition during mammary tumor growth in rats with controlled fat intake. | 1995 | Nutr Cancer | pmid:8610049 |
Ntambi JM et al. | A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8607881 |
Yiin SJ and Lin TH | Lead-catalyzed peroxidation of essential unsaturated fatty acid. | 1995 | Biol Trace Elem Res | pmid:8605084 |
Siguel EN | Dietary sources of long-chain n-3 polyunsaturated fatty acids. | 1996 | JAMA | pmid:8596214 |
Guil JL et al. | Identification of fatty acids in edible wild plants by gas chromatography. | 1996 | J Chromatogr A | pmid:8589832 |