alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

Cross Reference

Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Hearing Loss, High-Frequency D006316 1 associated lipids
Night Blindness D009755 1 associated lipids
Otorhinolaryngologic Neoplasms D010039 2 associated lipids
Spinal Cord Ischemia D020760 2 associated lipids
Mental Fatigue D005222 3 associated lipids
Depression, Postpartum D019052 3 associated lipids
Torsades de Pointes D016171 2 associated lipids
Dyskinesias D020820 3 associated lipids
Aging, Premature D019588 1 associated lipids
Insect Bites and Stings D007299 4 associated lipids
Per page 10 20 50 100 | Total 104

PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 2471
Authors Title Published Journal PubMed Link
Hadjighassem M et al. Oral consumption of α-linolenic acid increases serum BDNF levels in healthy adult humans. 2015 Nutr J pmid:25889793
Shomonov-Wagner L et al. Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning. 2015 Lipids Health Dis pmid:25889505
Machado AM et al. Effects of brown and golden flaxseed on the lipid profile, glycemia, inflammatory biomarkers, blood pressure and body composition in overweight adolescents. 2015 Nutrition pmid:25441591
Perng W et al. Alpha-linolenic acid (ALA) is inversely related to development of adiposity in school-age children. 2015 Eur J Clin Nutr pmid:25271016
Guichardant M et al. Omega-3 polyunsaturated fatty acids and oxygenated metabolism in atherothrombosis. 2015 Biochim. Biophys. Acta pmid:25263947
He J et al. Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis. 2015 Yeast pmid:26284451
Valenzuela R et al. Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. 2015 Nutrients pmid:26247968
Koh AS et al. The association between dietary omega-3 fatty acids and cardiovascular death: the Singapore Chinese Health Study. 2015 Eur J Prev Cardiol pmid:24343844
Keim SA and Branum AM Dietary intake of polyunsaturated fatty acids and fish among US children 12-60 months of age. 2015 Matern Child Nutr pmid:24034437
Shivashankar S and Sumathi M Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination? 2015 J. Biosci. pmid:25963264
Reinders I et al. Plasma phospholipid PUFAs are associated with greater muscle and knee extension strength but not with changes in muscle parameters in older adults. 2015 J. Nutr. pmid:25355842
Perumalsamy H et al. Larvicidal activity and possible mode of action of four flavonoids and two fatty acids identified in Millettia pinnata seed toward three mosquito species. 2015 Parasit Vectors pmid:25928224
Wiest EF et al. Association of serum aryl hydrocarbon receptor activity and RBC omega-3 polyunsaturated fatty acids with flow-mediated dilation in healthy, young Hispanic cigarette smokers. 2015 Toxicol. Lett. pmid:25482063
Lewinska A et al. Fatty Acid Profile and Biological Activities of Linseed and Rapeseed Oils. 2015 Molecules pmid:26703545
Liu X et al. APA-style human milk fat analogue from silkworm pupae oil: Enzymatic production and improving storage stability using alkyl caffeates. 2015 Sci Rep pmid:26643045
Mason JK et al. α-linolenic acid and docosahexaenoic acid, alone and combined with trastuzumab, reduce HER2-overexpressing breast cancer cell growth but differentially regulate HER2 signaling pathways. 2015 Lipids Health Dis pmid:26282560
Pan P et al. Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles. 2015 Carcinogenesis pmid:26246425
Cole C et al. Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice. 2015 BMC Complement Altern Med pmid:26243305
Jubie S et al. Isolation of methyl gamma linolenate from Spirulina platensis using flash chromatography and its apoptosis inducing effect. 2015 BMC Complement Altern Med pmid:26238515
Han H et al. Flaxseed Oil Containing α -Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice. 2015 Oxid Med Cell Longev pmid:26180602
Chen W et al. Effect of flaxseed on the fatty acid profile of egg yolk and antioxidant status of their neonatal offspring in Huoyan geese. 2015 Animal pmid:26173627
Sun L et al. Coccomyxa Gloeobotrydiformis Improves Learning and Memory in Intrinsic Aging Rats. 2015 Int. J. Biol. Sci. pmid:26078724
Folino A et al. Alpha-linolenic acid protects against cardiac injury and remodelling induced by beta-adrenergic overstimulation. 2015 Food Funct pmid:26068025
Shang X et al. Dietary α-Linolenic Acid and Total ω-3 Fatty Acids Are Inversely Associated with Abdominal Aortic Calcification in Older Women, but Not in Older Men. 2015 J. Nutr. pmid:26041673
Nieman DC et al. No positive influence of ingesting chia seed oil on human running performance. 2015 Nutrients pmid:25988762
Domenichiello AF et al. Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain? 2015 Prog. Lipid Res. pmid:25920364
Kawakami Y et al. Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study. 2015 Nutr J pmid:25896182
Salazar MO et al. A thin-layer chromatography autographic method for the detection of inhibitors of the Salmonella PhoP-PhoQ regulatory system. 2014 Mar-Apr Phytochem Anal pmid:24185747
Petrogianni M et al. Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention. 2014 Public Health Nutr pmid:23249766
Ponnampalam EN et al. Health beneficial long chain omega-3 fatty acid levels in Australian lamb managed under extensive finishing systems. 2014 Meat Sci. pmid:23643471
Hoogeveen EK et al. Effect of omega-3 fatty acids on kidney function after myocardial infarction: the Alpha Omega Trial. 2014 Clin J Am Soc Nephrol pmid:25104273
Hwang E et al. Coriander leaf extract exerts antioxidant activity and protects against UVB-induced photoaging of skin by regulation of procollagen type I and MMP-1 expression. 2014 J Med Food pmid:25019675
dos Santos AL et al. Dietary fat composition and cardiac events in patients with type 2 diabetes. 2014 Atherosclerosis pmid:25014032
Caligiuri SP et al. The HYPERFlax trial for determining the anti-HYPERtensive effects of dietary flaxseed in newly diagnosed stage 1 hypertensive patients: study protocol for a randomized, double-blinded, controlled clinical trial. 2014 Trials pmid:24938224
Baumgartner J et al. Providing male rats deficient in iron and n-3 fatty acids with iron and alpha-linolenic acid alone affects brain serotonin and cognition differently from combined provision. 2014 Lipids Health Dis pmid:24928171
Marklund M et al. A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy Nordic diet in individuals with metabolic syndrome. 2014 J. Nutr. pmid:25080537
Purushothaman D et al. Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs. 2014 Genet. Mol. Res. pmid:25078588
Hellstrand S et al. Genetic variation in FADS1 has little effect on the association between dietary PUFA intake and cardiovascular disease. 2014 J. Nutr. pmid:25008580
Herchi W et al. Flaxseed hull: Chemical composition and antioxidant activity during development. 2014 J Oleo Sci pmid:24919478
Morris JB et al. Flavonol content, oil%, and fatty acid composition variability in seeds of Teramnus labialis and T. uncinatus accessions with nutraceutical potential. 2014 J Diet Suppl pmid:25054688
Mariutto M et al. Reprogramming of fatty acid and oxylipin synthesis in rhizobacteria-induced systemic resistance in tomato. 2014 Plant Mol. Biol. pmid:24146221
Matravadia S et al. Both linoleic and α-linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats. 2014 Am. J. Physiol. Endocrinol. Metab. pmid:24844257
Sánchez-Reyes OB et al. Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation. 2014 Eur. J. Pharmacol. pmid:24239485
Berasategi I et al. Healthy reduced-fat Bologna sausages enriched in ALA and DHA and stabilized with Melissa officinalis extract. 2014 Meat Sci. pmid:24334039
Sengupta A and Ghosh M Effect of sterol esters on lipid composition and antioxidant status of erythrocyte membrane of hypercholesterolemic rats. 2014 J Oleo Sci pmid:24770475
Yuan X et al. Accumulation of eicosapolyenoic acids enhances sensitivity to abscisic acid and mitigates the effects of drought in transgenic Arabidopsis thaliana. 2014 J. Exp. Bot. pmid:24609499
Berasategi I et al. Reduced-fat bologna sausages with improved lipid fraction. 2014 J. Sci. Food Agric. pmid:24105447
Vedtofte MS et al. Association between the intake of α-linolenic acid and the risk of CHD. 2014 Br. J. Nutr. pmid:24964401
Yavin E et al. Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency. 2014 Biochim. Biophys. Acta pmid:24960100
Liang CH et al. Synthesis of doxorubicin α-linolenic acid conjugate and evaluation of its antitumor activity. 2014 Mol. Pharm. pmid:24720787