MeSH term | MeSH ID | Detail |
---|---|---|
Irritable Bowel Syndrome | D043183 | 8 associated lipids |
Overweight | D050177 | 11 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wu A et al. | Curcumin boosts DHA in the brain: Implications for the prevention of anxiety disorders. | 2015 | Biochim. Biophys. Acta | pmid:25550171 |
Kaka A et al. | α-Linolenic acid supplementation in BioXcell® extender can improve the quality of post-cooling and frozen-thawed bovine sperm. | 2015 | Anim. Reprod. Sci. | pmid:25544152 |
Machado AM et al. | Effects of brown and golden flaxseed on the lipid profile, glycemia, inflammatory biomarkers, blood pressure and body composition in overweight adolescents. | 2015 | Nutrition | pmid:25441591 |
He J et al. | Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis. | 2015 | Yeast | pmid:26284451 |
Valenzuela R et al. | Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. | 2015 | Nutrients | pmid:26247968 |
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Amminger GP et al. | Predictors of treatment response in young people at ultra-high risk for psychosis who received long-chain omega-3 fatty acids. | 2015 | Transl Psychiatry | pmid:25585167 |
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Dodington DW et al. | Higher Intakes of Fruits and Vegetables, β-Carotene, Vitamin C, α-Tocopherol, EPA, and DHA Are Positively Associated with Periodontal Healing after Nonsurgical Periodontal Therapy in Nonsmokers but Not in Smokers. | 2015 | J. Nutr. | pmid:26423734 |
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Kim KR et al. | Selective Production of 9R-Hydroxy-10E,12Z,15Z-Octadecatrienoic Acid from α-Linolenic Acid in Perilla Seed Oil Hydrolyzate by a Lipoxygenase from Nostoc Sp. SAG 25.82. | 2015 | PLoS ONE | pmid:26379279 |
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Mansara PP et al. | Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231. | 2015 | PLoS ONE | pmid:26325577 |
Imran M et al. | Impact of extrusion processing conditions on lipid peroxidation and storage stability of full-fat flaxseed meal. | 2015 | Lipids Health Dis | pmid:26286266 |
Mason JK et al. | α-linolenic acid and docosahexaenoic acid, alone and combined with trastuzumab, reduce HER2-overexpressing breast cancer cell growth but differentially regulate HER2 signaling pathways. | 2015 | Lipids Health Dis | pmid:26282560 |
Pan P et al. | Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles. | 2015 | Carcinogenesis | pmid:26246425 |
Cole C et al. | Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice. | 2015 | BMC Complement Altern Med | pmid:26243305 |
Jubie S et al. | Isolation of methyl gamma linolenate from Spirulina platensis using flash chromatography and its apoptosis inducing effect. | 2015 | BMC Complement Altern Med | pmid:26238515 |
Salazar MO et al. | A thin-layer chromatography autographic method for the detection of inhibitors of the Salmonella PhoP-PhoQ regulatory system. | 2014 Mar-Apr | Phytochem Anal | pmid:24185747 |
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Aliferis KA et al. | A metabolic profiling strategy for the dissection of plant defense against fungal pathogens. | 2014 | PLoS ONE | pmid:25369450 |
Jung JY et al. | Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. | 2014 | Acta Derm. Venereol. | pmid:24553997 |
Belayachi L et al. | Retama monosperma n-hexane extract induces cell cycle arrest and extrinsic pathway-dependent apoptosis in Jurkat cells. | 2014 | BMC Complement Altern Med | pmid:24460687 |
Djoussé L et al. | Repeated versus single measurement of plasma omega-3 fatty acids and risk of heart failure. | 2014 | Eur J Nutr | pmid:24395612 |
Ebrahimi M et al. | Effects of oils rich in linoleic and α-linolenic acids on fatty acid profile and gene expression in goat meat. | 2014 | Nutrients | pmid:25255382 |
Domenichiello AF et al. | Whole body synthesis rates of DHA from α-linolenic acid are greater than brain DHA accretion and uptake rates in adult rats. | 2014 | J. Lipid Res. | pmid:24212299 |
Aki T et al. | Regulation of polyunsaturated fatty acid biosynthesis by seaweed fucoxanthin and its metabolite in cultured hepatocytes. | 2014 | Lipids | pmid:24174374 |
Singer SD et al. | Development and characterization of low α-linolenic acid Brassica oleracea lines bearing a novel mutation in a 'class a' FATTY ACID DESATURASE 3 gene. | 2014 | BMC Genet. | pmid:25167929 |
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Choi JI et al. | Development of microalga Scenedesmus dimorphus mutant with higher lipid content by radiation breeding. | 2014 | Bioprocess Biosyst Eng | pmid:24871276 |
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MartÃnez-RamÃrez HR et al. | Whole-body retention of α-linolenic acid and its apparent conversion to other n-3 PUFA in growing pigs are reduced with the duration of feeding α-linolenic acid. | 2014 | Br. J. Nutr. | pmid:24438755 |
Sugasini D et al. | Lymphatic transport of α-linolenic acid and its conversion to long chain n-3 fatty acids in rats fed microemulsions of linseed oil. | 2014 | Lipids | pmid:24338560 |
O'Callaghan N et al. | Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study. | 2014 | Nutrition | pmid:24342530 |
Caligiuri SP et al. | Flaxseed consumption reduces blood pressure in patients with hypertension by altering circulating oxylipins via an α-linolenic acid-induced inhibition of soluble epoxide hydrolase. | 2014 | Hypertension | pmid:24777981 |
Dal Bosco A et al. | Effect of dietary alfalfa on the fatty acid composition and indexes of lipid metabolism of rabbit meat. | 2014 | Meat Sci. | pmid:24036258 |
Javadi N et al. | GC-MS-based metabolite profiling of Cosmos caudatus leaves possessing alpha-glucosidase inhibitory activity. | 2014 | J. Food Sci. | pmid:24888400 |
Reiner WB et al. | Fatty acids in mountain gorilla diets: implications for primate nutrition and health. | 2014 | Am. J. Primatol. | pmid:24243235 |
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