MeSH term | MeSH ID | Detail |
---|---|---|
Stomatitis, Aphthous | D013281 | 1 associated lipids |
Endomyocardial Fibrosis | D004719 | 4 associated lipids |
Conjunctivitis, Allergic | D003233 | 1 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hadjighassem M et al. | Oral consumption of α-linolenic acid increases serum BDNF levels in healthy adult humans. | 2015 | Nutr J | pmid:25889793 |
Shomonov-Wagner L et al. | Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning. | 2015 | Lipids Health Dis | pmid:25889505 |
Blondeau N et al. | Alpha-linolenic acid: an omega-3 fatty acid with neuroprotective properties-ready for use in the stroke clinic? | 2015 | Biomed Res Int | pmid:25789320 |
Perng W et al. | Alpha-linolenic acid (ALA) is inversely related to development of adiposity in school-age children. | 2015 | Eur J Clin Nutr | pmid:25271016 |
Fu X et al. | Regulation of formation of volatile compounds of tea (Camellia sinensis) leaves by single light wavelength. | 2015 | Sci Rep | pmid:26567525 |
Guichardant M et al. | Omega-3 polyunsaturated fatty acids and oxygenated metabolism in atherothrombosis. | 2015 | Biochim. Biophys. Acta | pmid:25263947 |
Cespedes E et al. | Adipose tissue n-3 fatty acids and metabolic syndrome. | 2015 | Eur J Clin Nutr | pmid:25097001 |
Koh AS et al. | The association between dietary omega-3 fatty acids and cardiovascular death: the Singapore Chinese Health Study. | 2015 | Eur J Prev Cardiol | pmid:24343844 |
Keim SA and Branum AM | Dietary intake of polyunsaturated fatty acids and fish among US children 12-60 months of age. | 2015 | Matern Child Nutr | pmid:24034437 |
Shivashankar S and Sumathi M | Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination? | 2015 | J. Biosci. | pmid:25963264 |
Chen S et al. | Profiling of volatile compounds and associated gene expression and enzyme activity during fruit development in two cucumber cultivars. | 2015 | PLoS ONE | pmid:25799542 |
Hernandez LR et al. | Effect of plant growth regulators on fatty acids composition in Jatropha curcas L. callus culture. | 2015 | J Oleo Sci | pmid:25757437 |
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Jung SW et al. | Mechanism of antibacterial activity of liposomal linolenic acid against Helicobacter pylori. | 2015 | PLoS ONE | pmid:25793403 |
Wiest EF et al. | Association of serum aryl hydrocarbon receptor activity and RBC omega-3 polyunsaturated fatty acids with flow-mediated dilation in healthy, young Hispanic cigarette smokers. | 2015 | Toxicol. Lett. | pmid:25482063 |
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Liu X et al. | APA-style human milk fat analogue from silkworm pupae oil: Enzymatic production and improving storage stability using alkyl caffeates. | 2015 | Sci Rep | pmid:26643045 |
Piermartiri T et al. | α-Linolenic Acid, A Nutraceutical with Pleiotropic Properties That Targets Endogenous Neuroprotective Pathways to Protect against Organophosphate Nerve Agent-Induced Neuropathology. | 2015 | Molecules | pmid:26569216 |
Han H et al. | Flaxseed Oil Containing α -Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice. | 2015 | Oxid Med Cell Longev | pmid:26180602 |
Chen W et al. | Effect of flaxseed on the fatty acid profile of egg yolk and antioxidant status of their neonatal offspring in Huoyan geese. | 2015 | Animal | pmid:26173627 |
Sun L et al. | Coccomyxa Gloeobotrydiformis Improves Learning and Memory in Intrinsic Aging Rats. | 2015 | Int. J. Biol. Sci. | pmid:26078724 |
Folino A et al. | Alpha-linolenic acid protects against cardiac injury and remodelling induced by beta-adrenergic overstimulation. | 2015 | Food Funct | pmid:26068025 |
Shang X et al. | Dietary α-Linolenic Acid and Total ω-3 Fatty Acids Are Inversely Associated with Abdominal Aortic Calcification in Older Women, but Not in Older Men. | 2015 | J. Nutr. | pmid:26041673 |
Nieman DC et al. | No positive influence of ingesting chia seed oil on human running performance. | 2015 | Nutrients | pmid:25988762 |
Domenichiello AF et al. | Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain? | 2015 | Prog. Lipid Res. | pmid:25920364 |
Kawakami Y et al. | Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study. | 2015 | Nutr J | pmid:25896182 |
Salazar MO et al. | A thin-layer chromatography autographic method for the detection of inhibitors of the Salmonella PhoP-PhoQ regulatory system. | 2014 Mar-Apr | Phytochem Anal | pmid:24185747 |
Childs CE et al. | Increased dietary α-linolenic acid has sex-specific effects upon eicosapentaenoic acid status in humans: re-examination of data from a randomised, placebo-controlled, parallel study. | 2014 | Nutr J | pmid:25496415 |
Petrogianni M et al. | Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention. | 2014 | Public Health Nutr | pmid:23249766 |
Hwang E et al. | Coriander leaf extract exerts antioxidant activity and protects against UVB-induced photoaging of skin by regulation of procollagen type I and MMP-1 expression. | 2014 | J Med Food | pmid:25019675 |
dos Santos AL et al. | Dietary fat composition and cardiac events in patients with type 2 diabetes. | 2014 | Atherosclerosis | pmid:25014032 |
Caligiuri SP et al. | The HYPERFlax trial for determining the anti-HYPERtensive effects of dietary flaxseed in newly diagnosed stage 1 hypertensive patients: study protocol for a randomized, double-blinded, controlled clinical trial. | 2014 | Trials | pmid:24938224 |
Baumgartner J et al. | Providing male rats deficient in iron and n-3 fatty acids with iron and alpha-linolenic acid alone affects brain serotonin and cognition differently from combined provision. | 2014 | Lipids Health Dis | pmid:24928171 |
Rajaram S | Health benefits of plant-derived α-linolenic acid. | 2014 | Am. J. Clin. Nutr. | pmid:24898228 |
Høstmark AT and Haug A | The inverse association between relative abundances of oleic acid and arachidonic acid is related to alpha -linolenic acid. | 2014 | Lipids Health Dis | pmid:24885640 |
He F et al. | Perinatal α-linolenic acid availability alters the expression of genes related to memory and to epigenetic machinery, and the Mecp2 DNA methylation in the whole brain of mouse offspring. | 2014 | Int. J. Dev. Neurosci. | pmid:24866706 |
Hellstrand S et al. | Genetic variation in FADS1 has little effect on the association between dietary PUFA intake and cardiovascular disease. | 2014 | J. Nutr. | pmid:25008580 |
Herchi W et al. | Flaxseed hull: Chemical composition and antioxidant activity during development. | 2014 | J Oleo Sci | pmid:24919478 |
Morris JB et al. | Flavonol content, oil%, and fatty acid composition variability in seeds of Teramnus labialis and T. uncinatus accessions with nutraceutical potential. | 2014 | J Diet Suppl | pmid:25054688 |
Mariutto M et al. | Reprogramming of fatty acid and oxylipin synthesis in rhizobacteria-induced systemic resistance in tomato. | 2014 | Plant Mol. Biol. | pmid:24146221 |
Matravadia S et al. | Both linoleic and α-linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats. | 2014 | Am. J. Physiol. Endocrinol. Metab. | pmid:24844257 |
Hudson BD et al. | The molecular basis of ligand interaction at free fatty acid receptor 4 (FFA4/GPR120). | 2014 | J. Biol. Chem. | pmid:24860101 |
Gorina SS et al. | Detection and molecular cloning of CYP74Q1 gene: identification of Ranunculus acris leaf divinyl ether synthase. | 2014 | Biochim. Biophys. Acta | pmid:24863619 |
Yuan X et al. | Accumulation of eicosapolyenoic acids enhances sensitivity to abscisic acid and mitigates the effects of drought in transgenic Arabidopsis thaliana. | 2014 | J. Exp. Bot. | pmid:24609499 |
Berasategi I et al. | Reduced-fat bologna sausages with improved lipid fraction. | 2014 | J. Sci. Food Agric. | pmid:24105447 |
Vedtofte MS et al. | Association between the intake of α-linolenic acid and the risk of CHD. | 2014 | Br. J. Nutr. | pmid:24964401 |
Soto-Cerda BJ et al. | Association mapping of seed quality traits using the Canadian flax (Linum usitatissimum L.) core collection. | 2014 | Theor. Appl. Genet. | pmid:24463785 |
Yavin E et al. | Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency. | 2014 | Biochim. Biophys. Acta | pmid:24960100 |
Liang CH et al. | Synthesis of doxorubicin α-linolenic acid conjugate and evaluation of its antitumor activity. | 2014 | Mol. Pharm. | pmid:24720787 |