Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shin JA et al. | Oxidation Stability of O/W Emulsion Prepared with Linolenic Acid Enriched Diacylglycerol. | 2016 | J. Food Sci. | pmid:27627797 |
Yamanaka N et al. | Alpha-Linolenic Acid-Enriched Diacylglycerol Oil Suppresses the Postprandial Serum Triglyceride Level-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study. | 2016 | J. Nutr. Sci. Vitaminol. | pmid:28202845 |
Saito S et al. | Consumption of alpha-Linolenic Acid-enriched Diacylglycerol Reduces Visceral Fat Area in Overweight and Obese Subjects: a Randomized, Double-blind Controlled, Parallel-group Designed Trial. | 2016 | J Oleo Sci | pmid:27321122 |
Metherel AH et al. | Whole-body DHA synthesis-secretion kinetics from plasma eicosapentaenoic acid and alpha-linolenic acid in the free-living rat. | 2016 | Biochim. Biophys. Acta | pmid:27263420 |
Demizieux L et al. | Early Low-Fat Diet Enriched With Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High-Fat Diet Challenge in Mice. | 2016 | Diabetes | pmid:27207550 |
Bork CS et al. | Dietary intake and adipose tissue content of α-linolenic acid and risk of myocardial infarction: a Danish cohort study. | 2016 | Am. J. Clin. Nutr. | pmid:27169831 |
Esquivel-Hernández DA et al. | Supercritical Carbon Dioxide and Microwave-Assisted Extraction of Functional Lipophilic Compounds from Arthrospira platensis. | 2016 | Int J Mol Sci | pmid:27164081 |
Campidonico L et al. | Fatty acid composition of ruminal digesta and longissimus muscle from lambs fed silage mixtures including red clover, sainfoin, and timothy. | 2016 | J. Anim. Sci. | pmid:27136014 |
Bourourou M et al. | Alpha-linolenic acid given as enteral or parenteral nutritional intervention against sensorimotor and cognitive deficits in a mouse model of ischemic stroke. | 2016 | Neuropharmacology | pmid:27133376 |
Tian Y et al. | Perilla Oil Has Similar Protective Effects of Fish Oil on High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease and Gut Dysbiosis. | 2016 | Biomed Res Int | pmid:27051672 |
Jablonická V et al. | Identification of a secretory phospholipase A2 from Papaver somniferum L. that transforms membrane phospholipids. | 2016 | Phytochemistry | pmid:27473012 |
Cinelli G et al. | Influence of Maternal Obesity and Gestational Weight Gain on Maternal and Foetal Lipid Profile. | 2016 | Nutrients | pmid:27314385 |
Garsetti M et al. | Fat composition of vegetable oil spreads and margarines in the USA in 2013: a national marketplace analysis. | 2016 | Int J Food Sci Nutr | pmid:27046021 |
Machado AM et al. | Effects of brown and golden flaxseed on the lipid profile, glycemia, inflammatory biomarkers, blood pressure and body composition in overweight adolescents. | 2015 | Nutrition | pmid:25441591 |
He J et al. | Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis. | 2015 | Yeast | pmid:26284451 |
Valenzuela R et al. | Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. | 2015 | Nutrients | pmid:26247968 |
Running CA and Mattes RD | Humans are more sensitive to the taste of linoleic and α-linolenic than oleic acid. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:25540234 |
Mansara PP et al. | Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231. | 2015 | PLoS ONE | pmid:26325577 |
Imran M et al. | Impact of extrusion processing conditions on lipid peroxidation and storage stability of full-fat flaxseed meal. | 2015 | Lipids Health Dis | pmid:26286266 |
Mason JK et al. | α-linolenic acid and docosahexaenoic acid, alone and combined with trastuzumab, reduce HER2-overexpressing breast cancer cell growth but differentially regulate HER2 signaling pathways. | 2015 | Lipids Health Dis | pmid:26282560 |