Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Shirasaka N et al. | Microbial synthesis of trans isomer of eicosapentaenoic acid (EPA) from the chemically synthesized trans isomer of linolenic acid by a delta12 desaturase-defective mutant of Mortierella alpina 1S-4. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12834302 |
Mori N et al. | Identification of volicitin-related compounds from the regurgitant of lepidopteran caterpillars. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12834303 |
Hosokawa M et al. | Production of novel tetrahydroxyfuranyl fatty acids from alpha-linolenic acid by Clavibacter sp. strain ALA2. | 2003 | Appl. Environ. Microbiol. | pmid:12839755 |
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Daligault F et al. | Mechanistic characterization of omega-3 desaturation in the green alga Chlorella vulgaris. | 2003 | Phytochemistry | pmid:12877913 |
Ratnayake WM and Gilani GS | Protective effects of flax meal against hypercholesterolemia and hypertriglyceridemia in rats. | 2003 | J Am Coll Nutr | pmid:12897048 |
Mulder C et al. | Decreased lysophosphatidylcholine/phosphatidylcholine ratio in cerebrospinal fluid in Alzheimer's disease. | 2003 | J Neural Transm | pmid:12898349 |
Miyazawa D et al. | Dietary alpha-linolenic acid suppresses the formation of lysophosphatidic acid, a lipid mediator, in rat platelets compared with linoleic acid. | 2003 | Life Sci. | pmid:12899931 |
Mashek DG and Grummer RR | Effects of long chain fatty acids on lipid and glucose metabolism in monolayer cultures of bovine hepatocytes. | 2003 | J. Dairy Sci. | pmid:12906057 |
Burdge GC and Wootton SA | Conversion of alpha-linolenic acid to palmitic, palmitoleic, stearic and oleic acids in men and women. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12907139 |
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Kouba M et al. | Effect of a high-linolenic acid diet on lipogenic enzyme activities, fatty acid composition, and meat quality in the growing pig. | 2003 | J. Anim. Sci. | pmid:12926779 |
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Looking for the number-one omega-3. All three varieties are probably good for you, but evidence for the EPA and DHA in fish is the strongest. | 2003 | Harv Health Lett | pmid:12936877 | |
Dewhurst RJ et al. | Comparison of grass and legume silages for milk production. 2. In vivo and in sacco evaluations of rumen function. | 2003 | J. Dairy Sci. | pmid:12939085 |
Lang-Lazdunski L et al. | Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats. | 2003 | J. Vasc. Surg. | pmid:12947278 |
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Schmelz EA et al. | Nitrogen deficiency increases volicitin-induced volatile emission, jasmonic acid accumulation, and ethylene sensitivity in maize. | 2003 | Plant Physiol. | pmid:12970495 |
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Cunnane S | Cholesterol lowering by alpha-linolenic acid. | 1992 | Am. J. Clin. Nutr. | pmid:1345883 |
Yamazaki K et al. | Comparison of the conversion rates of alpha-linolenic acid (18:3(n - 3)) and stearidonic acid (18:4(n - 3)) to longer polyunsaturated fatty acids in rats. | 1992 | Biochim. Biophys. Acta | pmid:1346092 |
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