alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Insulin Resistance D007333 99 associated lipids
Learning Disorders D007859 11 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Diseases D008107 31 associated lipids
Long QT Syndrome D008133 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Myocardial Infarction D009203 21 associated lipids
Neoplasms D009369 13 associated lipids
Neuroblastoma D009447 66 associated lipids
Night Blindness D009755 1 associated lipids
Otorhinolaryngologic Neoplasms D010039 2 associated lipids
Pain D010146 64 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Pancytopenia D010198 6 associated lipids
Paraplegia D010264 8 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Precancerous Conditions D011230 48 associated lipids
Pregnancy Complications D011248 19 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Retinal Degeneration D012162 9 associated lipids
Retinitis Pigmentosa D012174 6 associated lipids
Retinoblastoma D012175 12 associated lipids
Sebaceous Gland Neoplasms D012626 2 associated lipids
Seizures D012640 87 associated lipids
Stomatitis, Aphthous D013281 1 associated lipids
Thrombosis D013927 49 associated lipids
Tuberculosis D014376 20 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Weight Gain D015430 101 associated lipids
Torsades de Pointes D016171 2 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Depression, Postpartum D019052 3 associated lipids
Aging, Premature D019588 1 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Stroke D020521 32 associated lipids
Spinal Cord Ischemia D020760 2 associated lipids
Dyskinesias D020820 3 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Per page 10 20 50 100 | Total 2471
Authors Title Published Journal PubMed Link
Djoussé L et al. Repeated versus single measurement of plasma omega-3 fatty acids and risk of heart failure. 2014 Eur J Nutr pmid:24395612
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Botelho PB et al. Effect of Echium oil compared with marine oils on lipid profile and inhibition of hepatic steatosis in LDLr knockout mice. 2013 Lipids Health Dis pmid:23510369
Kastner DW and Van Wagoner DR Diet and atrial fibrillation: does α-linolenic acid, a plant derived essential fatty acid, have an impact? 2013 J Am Heart Assoc pmid:23525415
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Zhang W et al. Alpha-linolenic acid intake prevents endothelial dysfunction in high-fat diet-fed streptozotocin rats and underlying mechanisms. 2013 VASA pmid:24220118
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Caligiuri SP et al. Dietary linoleic acid and α-linolenic acid differentially affect renal oxylipins and phospholipid fatty acids in diet-induced obese rats. 2013 J. Nutr. pmid:23902961
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