Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.
To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Colquhoun A | Induction of apoptosis by polyunsaturated fatty acids and its relationship to fatty acid inhibition of carnitine palmitoyltransferase I activity in Hep2 cells. | 1998 | Biochem. Mol. Biol. Int. | pmid:9678254 |
Schwab US et al. | The effect of quality and amount of dietary fat on the susceptibility of low density lipoprotein to oxidation in subjects with impaired glucose tolerance. | 1998 | Eur J Clin Nutr | pmid:9683400 |
Suzuki H et al. | Long-term effect of a trace amount of tea catechins with perilla oil on the plasma lipids in mice. | 1998 | Int J Vitam Nutr Res | pmid:9706503 |
Ryu SB and Wang X | Increase in free linolenic and linoleic acids associated with phospholipase D-mediated hydrolysis of phospholipids in wounded castor bean leaves. | 1998 | Biochim. Biophys. Acta | pmid:9714802 |
Yu G et al. | Fatty acid composition in colostrum and mature milk from non-atopic and atopic mothers during the first 6 months of lactation. | 1998 | Acta Paediatr. | pmid:9722244 |
Belzung C et al. | Alpha-linolenic acid deficiency modifies distractibility but not anxiety and locomotion in rats during aging. | 1998 | J. Nutr. | pmid:9732316 |
Menard CR et al. | Recycling of carbon into lipids synthesized de novo is a quantitatively important pathway of alpha-[U-13C]linolenate utilization in the developing rat brain. | 1998 | J. Neurochem. | pmid:9798942 |
Bretillon L et al. | Desaturation and chain elongation of [1-14C]mono-trans isomers of linoleic and alpha-linolenic acids in perfused rat liver. | 1998 | J. Lipid Res. | pmid:9799809 |
Furuno K et al. | Lipid peroxidation induced by adriamycin in linolenic acid-loaded cultured hepatocytes. | 1998 | Pharmacol. Toxicol. | pmid:9820879 |
Pang D et al. | Replacement of linoleic acid with alpha-linolenic acid does not alter blood lipids in normolipidaemic men. | 1998 | Br. J. Nutr. | pmid:9828757 |
Parchmann S and Mueller MJ | Evidence for the formation of dinor isoprostanes E1 from alpha-linolenic acid in plants. | 1998 | J. Biol. Chem. | pmid:9830005 |
Gu JY et al. | Effect of dietary fats and sesamin on the lipid metabolism and immune function of Sprague-Dawley rats. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9836427 |
Hamberg M | A pathway for biosynthesis of divinyl ether fatty acids in green leaves. | 1998 | Lipids | pmid:9870900 |
Su HM et al. | Bioequivalence of dietary alpha-linolenic and docosahexaenoic acids as sources of docosahexaenoate accretion in brain and associated organs of neonatal baboons. | 1999 | Pediatr. Res. | pmid:9890614 |
Allman-Farinelli MA et al. | Comparison of the effects of two low fat diets with different alpha-linolenic:linoleic acid ratios on coagulation and fibrinolysis. | 1999 | Atherosclerosis | pmid:9920517 |
Tranchant T et al. | Long-term supplementation of culture medium with essential fatty acids alters alpha-linolenic acid uptake in Caco-2 clone TC7. | 1998 | Can. J. Physiol. Pharmacol. | pmid:9923400 |
Chyb S et al. | Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL. | 1999 | Nature | pmid:9930700 |
Rao MS et al. | Yield, protein, and oil quality of soybean genotypes selected for tofu production. | 1998 | Plant Foods Hum Nutr | pmid:9950085 |
Weisinger HS et al. | Effects of dietary n-3 fatty acid deficiency and repletion in the guinea pig retina. | 1999 | Invest. Ophthalmol. Vis. Sci. | pmid:9950590 |
Ihara M et al. | Comparative effects of short- and long-term feeding of safflower oil and perilla oil on lipid metabolism in rats. | 1998 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9972297 |
Leaf A | Dietary prevention of coronary heart disease: the Lyon Diet Heart Study. | 1999 | Circulation | pmid:9989956 |