alpha-linolenic acid

Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified.

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Introduction

To understand associated biological information of alpha-linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-linolenic acid?

alpha-linolenic acid is suspected in Coronary heart disease, Arterial thrombosis, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-linolenic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypertension D006973 115 associated lipids
Inflammation D007249 119 associated lipids
Insect Bites and Stings D007299 4 associated lipids
Insulin Resistance D007333 99 associated lipids
Learning Disorders D007859 11 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Diseases D008107 31 associated lipids
Long QT Syndrome D008133 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Myocardial Infarction D009203 21 associated lipids
Neoplasms D009369 13 associated lipids
Neuroblastoma D009447 66 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with alpha-linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-linolenic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-linolenic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with alpha-linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-linolenic acid

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Authors Title Published Journal PubMed Link
Calder PC omega 3 polyunsaturated fatty acids, inflammation and immunity. 2001 World Rev Nutr Diet pmid:11935943
Williard DE et al. Production and release of docosahexaenoic acid by differentiated rat brain astrocytes. 2001 World Rev Nutr Diet pmid:11935950
Cunnane SC New developments in alpha-linolenate metabolism with emphasis on the importance of beta-oxidation and carbon recycling. 2001 World Rev Nutr Diet pmid:11935952
Okuyama H et al. alpha-linolenate-deficiency-induced alterations in brightness discrimination learning behavior and retinal function in rats. 2001 World Rev Nutr Diet pmid:11935967
Howe PR Omega 3 fatty acids--an Australian perspective. 1998 World Rev Nutr Diet pmid:9648518
Okuyama H et al. Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. 2007 World Rev Nutr Diet pmid:17167282
Yang X et al. [Effects of silkworm pupa oil on serum lipids level and platelet function in rats]. 2002 Wei Sheng Yan Jiu pmid:12600031
Jiang M et al. [Protective effect of ALA on high glucose induced cellular injury of LLC-PK1 cell]. 2012 Wei Sheng Yan Jiu pmid:22611923
Zhang G et al. [Effects of fatty acids on proliferation and differentiation of myoblast]. 2012 Wei Sheng Yan Jiu pmid:23424861
Fein A and Cavar S Divergent mechanisms for phototransduction of invertebrate microvillar photoreceptors. 2000 Nov-Dec Vis. Neurosci. pmid:11193107